Investigating Sensitivity Issues - Thermo Scientific ISQ 7000 Hardware Manual

2
Troubleshooting

Investigating Sensitivity Issues

Investigating Sensitivity Issues
138 ISQ 7000 Hardware Manual
The most common and anticipated causes of loss of sensitivity that cause tuning to fail are
contamination leading to necessary ion source cleaning and loss of calibration gas intensity
due to depletion of the calibration gas. Sensitivity issues are usually the result of an air leak,
dirty components, or contamination. Sometimes sensitivity issues can be caused by simple
problems to fix such as running out of carrier gas or a sample failing to inject into the GC.
Before troubleshooting for sensitivity issues, look for the simple problems. If the problem is
more complex, then check for air leaks or dirty components. You can prevent these types of
problems by properly cleaning and maintaining your GC/MS system. It is normal to see a
decrease in sensitivity in the first few injections on a clean system.
Before troubleshooting for sensitivity issues, look for simple solutions, such as fixing a clogged
autosampler syringe or raising the level of your sample. You should also check the calibration
gas vial. Calibration gas needs to be replaced about every two years. You can always prevent
sensitivity issues from occurring by keeping your GC/MS system clean and free of
contamination.
WARNING ELECTRICAL SHOCK HAZARD: When troubleshooting any issue that requires
removing a cover on the ISQ 7000 mass spectrometer, you should power-off and vent the
instrument to avoid harming yourself.
AVERTISSEMENT RISQUE D'ÉLECTROCUTION : lorsque vous cherchez à résoudre un
problème nécessitant d'enlever le couvercle du spectromètre de masse ISQ 7000, mettez
hors tension et ventilez l'instrument pour éviter de vous blesser.
Thermo Scientific