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Thermo Scientific ISQ 7000 Hardware Manual

Mass spectrometers
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ISQ 7000
Mass Spectrometers
Hardware Manual
1R120617-0002 Revision C
December 2018

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  • Page 1 ISQ 7000 Mass Spectrometers Hardware Manual 1R120617-0002 Revision C December 2018...
  • Page 2 Sale shall govern all conflicting information between the two documents. Release history: Revision A, March 2018; Revision B, April 2018; Revision C, December 2018. Software version: Thermo Scientific ISQ Series 4.0 or later. For Research Use Only. Not for use in diagnostic procedures.

  • Page 3: Table Of Contents

    Maintenance Supplies and Tools ........4 Configuring the ISQ 7000 Mass Spectrometer ......6 Powering On the ISQ 7000 Mass Spectrometer .
  • Page 4 Software is not communicating with the ISQ 7000 system....122 Cannot download methods to the ISQ 7000 system....122 GC does not start or is not ready.
  • Page 5 Investigating Power Supply Issues ........136 The ISQ 7000 instrument will not power-on......136 The ISQ 7000 instrument powers on temporarily and trips the circuit breaker.
  • Page 6 Anode Feedthrough......... . . 265 Upgrading the ISQ 7000 System Software ......269 Updating the Firmware on the Instrument .
  • Page 7 Contents Replacing the Boards in the ISQ 7000 Mass Spectrometer ....292 RF Board and Rod Driver Board ....... . . 293 RF Board/Rod Driver Board Kit .
  • Page 9 • Direct Probe Controller (DPC) standards: EMC: EN 61326-1:2013. Safety: IEC 61010-1:2001, IEC 61010-2-081:2001 • ISQ and ISQ 7000 standards: EMC: EN 61326-1:2013. Safety: IEC 61010-1:2010 (ed. 3); IEC 61010-2- 081:2015 (ed. 2); IEC 61010-2-010:2014 (ed. 3); IECEE CB SCHEME CERT NO. DE 3-30000 •...
  • Page 10 à l’utilisation sûre de ce produit, avant d’utiliser le dispositif. Notice on Lifting and Handling of Thermo Scientific Instruments For your safety, and in compliance with international regulations, the physical handling of this Thermo Fisher Scientific instrument requires a team effort to lift and/or move the instrument. This instrument is too heavy and/or bulky for one person alone to handle safely.
  • Page 11 Notice on the Susceptibility to Electromagnetic Transmissions Your instrument is designed to work in a controlled electromagnetic environment. Do not use radio frequency transmitters, such as mobile phones, in close proximity to the instrument. For manufacturing location, see the label on the instrument. WEEE Compliance This product is required to comply with the European Union’s Waste Electrical &...
  • Page 12 WEEE Konformität Dieses Produkt muss die EU Waste Electrical & Electronic Equipment (WEEE) Richtlinie 2002/96/EC erfüllen. Das Produkt ist durch folgendes Symbol gekennzeichnet: Thermo Fisher Scientific hat Vereinbarungen mit Verwertungs-/Entsorgungsfirmen in allen EU-Mitgliedsstaaten getroffen, damit dieses Produkt durch diese Firmen wiederverwertet oder entsorgt werden kann. Mehr Information über die Einhaltung dieser Anweisungen durch Thermo Fisher Scientific, über die Verwerter, und weitere Hinweise, die nützlich sind, um die Produkte zu identifizieren, die unter diese RoHS Anweisung fallen, finden sie unter www.thermoscientific.com/rohsweee.

  • Page 13: Preface

    WARNING Thermo Scientific systems operate safely and reliably under carefully controlled environmental conditions. If the equipment is used in a manner not specified by the manufacturer, the protections provided by the equipment might be impaired.

  • Page 14: Related Documentation

    • From the ISQ window in the instrument control software, choose Help > ISQ Help. • If available for a specific window or dialog box, click Help or press the F1 key for information about setting parameters. For more information, visit www.thermofisher.com. ISQ 7000 Hardware Manual Thermo Scientific...

  • Page 15: System Requirements

    • Microsoft™ Windows™ 10 Operating System (64-bit) English only or Windows 7 Professional Operating System (64-bit) • Microsoft .NET Framework 4.0 or later • Thermo Scientific™ Xcalibur™ and Foundation software • Thermo Scientific™ TraceFinder™ software • Thermo Scientific™ Dionex™ Chromeleon software Check release notes for compatibility with ISQ Series instrument control software.

  • Page 16: Safety Symbols And Signal Words

    This damage might not be covered under the standard warranty. LIFTING HAZARD: Indicates that a physical injury could or might occur if two or more people do not lift an object. ISQ 7000 Hardware Manual Thermo Scientific...
  • Page 17 RISQUE DE BRÛLURE : vous avertit de la présence d’une surface chaude qui peut ou pourrait entraîner des blessures par brûlure. RISQUE D’ÉLECTROCUTION : indique qu’un choc électrique peut ou pourrait survenir. Thermo Scientific ISQ 7000 Hardware Manual xvii...
  • Page 18 CONSULTER LE MANUEL : vous avertit de lire attentivement la documentation de votre instrument afin de garantir votre sécurité et la capacité opérationnelle de l’instrument. Ne pas lire attentivement la documentation peut ou pourrait vous exposer à un risque de blessure physique. xviii ISQ 7000 Hardware Manual Thermo Scientific...

  • Page 19: Hydrogen Safety Precautions

    Before you begin using hydrogen, you should conduct a risk assessment based on the quantity of hydrogen to be used and the conditions of your laboratory. You should ask yourself: “What hydrogen hazards associated with this project are most likely to occur?” Thermo Scientific ISQ 7000 Hardware Manual...
  • Page 20 • There should also be contingency plans in place should an incident occur. • The site emergency response team, as well as the local fire department, should know the location of all hydrogen storage tanks. ISQ 7000 Hardware Manual Thermo Scientific...

  • Page 21: Using Hydrogen With Isq 7000 Mass Spectrometers

    Hydrogen Safety Precautions Using Hydrogen with ISQ 7000 Mass Spectrometers To use hydrogen with the ISQ 7000 instrument, you must always shut off the GC carrier gas before venting or turning off the ISQ 7000 instrument. There are three hydrogen safety screws on the ISQ 7000 instrument that must be in place.
  • Page 22 If a hydrogen cylinder or hydrogen generation system is located within immediate reach, a separate point-of-use shutoff valve is usually not necessary. Line regulators that have their source away from the point of use should have a manual shutoff valve near the point of use. xxii ISQ 7000 Hardware Manual Thermo Scientific...

  • Page 23: Purchasing Hydrogen

    Properly Storing Hydrogen Storing and handling compressed hydrogen gas and cryogenic liquid hydrogen present potential health and safety hazards. Using proper storage and handling techniques is essential to maintaining a safe work environment. Thermo Scientific ISQ 7000 Hardware Manual xxiii...
  • Page 24 • As liquid hydrogen systems also have a cryogenic hazard, additional safety considerations for the use of cryogenic liquids may be necessary. xxiv ISQ 7000 Hardware Manual Thermo Scientific...

  • Page 25: Hydrogen Safety Codes, Standards And References

    • NFPA 55, Standard for the Storage, Use, and Handling of Compressed Gases and Cryogenic Fluids in Portable and Stationary Containers, Cylinders, and Tanks, 2005 Edition • NFPA 68, Standard on Explosion Protection by Deflagration Venting • NFPA 70, National Electrical Code Thermo Scientific ISQ 7000 Hardware Manual...

  • Page 26: Hazardous Substances Precautions

    AVERTISSEMENT Avant d’utiliser des substances dangereuses (toxiques, nocives, etc.), veuillez lire attentivement les indications et informations relatives au risque reprises sur la fiche de données de sécurité adéquate. Utilisez un équipement de protection individuelle conformément aux exigences de sécurité. xxvi ISQ 7000 Hardware Manual Thermo Scientific...

  • Page 27: Biological Hazard Warning Note

    Consult local environmental and safety regulations for instructions in exhausting fumes from your system. Contacting Us There are several ways to contact Thermo Fisher Scientific for the information you need. Thermo Scientific ISQ 7000 Hardware Manual xxvii...
  • Page 28 Go to www.unitylabservices.com/en/home.html.  To suggest changes to documentation or to Help • Fill out a reader survey online at www.surveymonkey.com/s/PQM6P62. • Send an e-mail message to the Technical Publications Editor at techpubs-austin@thermofisher.com. xxviii ISQ 7000 Hardware Manual Thermo Scientific...

  • Page 29: Chapter 1 Performing Routine Maintenance

    Performing Routine Maintenance This chapter describes how to perform routine maintenance on the ISQ 7000 mass spectrometer. Keeping your ISQ 7000 instrument in good working condition increases laboratory productivity and helps you get the most out of the instrument. Contents •...
  • Page 30 (ammonia, etc.), you may need to change the oil more often. The foreline pump must be replaced if it seizes up. There are many more components of the ISQ 7000 instrument that do not require routine maintenance, but may need to be replaced in the event that there is a problem with the instrument.

  • Page 31: Maintenance Schedule

    You should choose a column that gives you the best possible resolution, analysis speed, and quantitation Thermo Scientific ISQ 7000 Hardware Manual...

  • Page 32: Maintenance Supplies And Tools

    Maintenance Supplies and Tools Maintenance Supplies and Tools To perform routine maintenance on the ISQ 7000 mass spectrometer, you will need the following supplies and tools. Table 1. Items in the MS Toolkit (Order if you have an instrument with no VPI...
  • Page 33 For this reason, clean room gloves are strongly recommended when handling the ion source cartridge. We recommend Cardinal Health CP100 Nitrile Cleanroom Gloves. See the ISQ and TSQ GC-MS Spare Parts Guide for ordering information. Thermo Scientific ISQ 7000 Hardware Manual...

  • Page 34: Configuring The Isq 7000 Mass Spectrometer

    When you receive your ISQ 7000 mass spectrometer, a Field Service Engineer will configure the system for you. However, if you need to reconfigure your ISQ system, follow these steps: 1. Place the ISQ 7000 instrument, GC, computer, monitor, and keyboard on a work table and the foreline pump on the floor underneath.
  • Page 35 5. Connect the GC communication cable to the COM1 or LAN port on the back of the computer. 6. Connect the Ethernet cable to the Data System connector on the ISQ 7000 instrument and to the bottom Ethernet port on the back of the computer.
  • Page 36 Performing Routine Maintenance Configuring the ISQ 7000 Mass Spectrometer 18. Connect the ISQ 7000 instrument’s electrical cable to the AC Input connector on the ISQ 7000 instrument and to the wall outlet. 19. Flip up the ISQ 7000 instrument’s power switch to power it on.

  • Page 37: Powering On The Isq 7000 Mass Spectrometer

    2. Be sure the GC is powered on and there is carrier gas flowing through the column into the ISQ 7000 instrument. CAUTION INSTRUMENT DAMAGE: If you power-on the ISQ 7000 instrument without column flow, air is drawn through the column, which could damage the instrument. This large air leak may also require that you clean the ion source.
  • Page 38 Power Switch Vent Valve Knob 5. Check the lights on the front of the instrument to make sure it is ready for use. Figure 3. Using the Lights on the ISQ 7000 Mass Spectrometer Busy Power Vacuum Heaters • Power—If the Power light is a solid green, the instrument is powered on. When the light is not lit, the instrument is not powered on.
  • Page 39 Performing Routine Maintenance Powering On the ISQ 7000 Mass Spectrometer • Vacuum—If Vacuum is slowly blinking orange, you have not achieved vacuum yet. If it is blinking orange quickly, you have a large leak that prevented the instrument from achieving vacuum. You need to turn the power off, find and fix the leak, and power-on the instrument.
  • Page 40 Performing Routine Maintenance Powering On the ISQ 7000 Mass Spectrometer 7. Check the heater status by clicking the Status tab in the ISQ 7000 Dashboard. If the ion source is not set to the right temperature, click the Instrument Control button and change the temperature.

  • Page 41: Powering Off The Isq 7000 Mass Spectrometer

    à vide. Reportez-vous aux « Précautions de sécurité relatives à l’hydrogène » à la page xvi de la préface pour plus d’informations. 3. Click Shut Down on the ISQ Dashboard or on the ISQ 7000 status page within the instrument software.
  • Page 42 Performing Routine Maintenance Powering Off the ISQ 7000 Mass Spectrometer 6. If you are using hydrogen as a carrier gas, unscrew the hydrogen safety screw on the front door. Figure 5. Powering Off the ISQ 7000 Instrument Power Switch Hydrogen Safety Screws...
  • Page 43 Powering Off the ISQ 7000 Mass Spectrometer IMPORTANT The process ends here if you are planning to perform system maintenance on the ISQ 7000 mass spectrometer alone (for example, to replace the filament). You don’t need to turn off the GC, data system, and autosampler.

  • Page 44: Replacing A Column

    Replacing a column in a ISQ 7000 system with no VPI or an AEI ion source If your ISQ 7000 system has no VPI or has an AEI ion source installed on the system, follow the instructions below to replace the column.
  • Page 45 Performing Routine Maintenance Replacing a Column 3. On the left side of the instrument, push down on the power switch to power-off the ISQ 7000 system. Figure 6. Powering Off the ISQ 7000 Instrument Power Switch Hydrogen Safety Screws Vent Valve Knob...
  • Page 46 1. Lower the oven temperature and allow it to cool. 2. If the ISQ 7000 system is running, shut down and vent it. See the instrument’s hardware manual for instructions. CAUTION BURN HAZARD: The injector, detectors, oven, and transfer line may be hot.
  • Page 47 12. Turn the spring loaded transfer line nut 1 flat (60°) backward so the column is able to move in the ferrule with slight resistance. 13. Line up the outlet of the column with the arrows on the end of the column measuring tool. Thermo Scientific ISQ 7000 Hardware Manual...
  • Page 48 15. Pull the column back from the spring loaded transfer line nut. Do not move the septum from its position on the column. Figure 11. Pulling the Column Back from the Spring Loaded Transfer Line Nut Spring Loaded Column Transfer Line Nut Septum ISQ 7000 Hardware Manual Thermo Scientific...
  • Page 49 20. Loosen the nut by turning it exactly 1 flat (60°) backward. 21. Position the column in the transfer line using the cut septum to measure the correct length you should insert the column. Thermo Scientific ISQ 7000 Hardware Manual...
  • Page 50 26. Close the front door of the GC. 27. Restore working conditions. a. Raise the oven temperature to the initial temperature that you will use. b. Turn on vacuum compensation on the GC. 28. Power on the ISQ 7000 instrument. ISQ 7000 Hardware Manual Thermo Scientific...
  • Page 51 6. Insert the column through the transfer line nut and ferrule, entering through the tapered end of the ferrule. Wipe the column again with a tissue soaked in methanol. Thermo Scientific ISQ 7000 Hardware Manual...
  • Page 52 12. Line up the outlet of the column with the arrows on the end of the column measuring tool. Figure 16. Lining Up the Column in the Column Measuring Tool Column Outlet ISQ 7000 Hardware Manual Thermo Scientific...
  • Page 53 16. Remove the column, transfer line nut and ferrule from the column measuring tool, making sure not to move the septum from its location on the column. 17. Insert the column into the transfer line. Thermo Scientific ISQ 7000 Hardware Manual...
  • Page 54 21. Tighten the nut 1 flat (60°) forward—back to where it is secure enough in the transfer line that you cannot move it. 22. Tighten the nut 1 additional quarter turn. 23. Remove the cut septum. ISQ 7000 Hardware Manual Thermo Scientific...

  • Page 55: Replacing A Column On A Isq 7000 System With A Vpi And An Extractabrite Ion Source

    Power on the ISQ 7000 instrument. Once the ISQ 7000 instrument is pumped own and able to scan, view air water spectra and look for evidence of leaks with a large m/z 28 signal. If you observe a leak, stop scanning and gently tighten the nut in small increments until no leaks appear when scanning.
  • Page 56 Performing Routine Maintenance Replacing a Column b. On the ISQ 7000 Dashboard set the MS transfer line temp to 40 °C and the ion source temp to 175 °C (to avoid excessive oxidation of source parts or contamination from the V-lock source plug).
  • Page 57 IMPORTANT The V-lock source plug should remain attached to the source exchange tool. Do not rotate the source exchange tool handle to attempt to disengage the source plug. Figure 23. V-lock Source Plug Inserted Correctly Thermo Scientific ISQ 7000 Hardware Manual...
  • Page 58 17. Choose an appropriate ferrule for the outer diameter of your column. 18. Insert the column through the spring loaded transfer line nut and ferrule, entering through the tapered end of the ferrule. 19. Wipe the column again with a tissue soaked in methanol. ISQ 7000 Hardware Manual Thermo Scientific...
  • Page 59 24. Wipe the column with an alcohol soaked-wipe after inserting through the ferrule. 25. Carefully push the column back into the GC transfer line while keeping the nut and ferrule on the column. Thermo Scientific ISQ 7000 Hardware Manual...
  • Page 60 Once the ISQ 7000 instrument is pumped down and able to scan, view air water spectra and look for evidence of leaks with a large m/z 28 signal. If you observe a leak, stop scanning and gently tighten the nut in small increments until no leaks appear when scanning.

  • Page 61: Installing The Column In The Gc Inlet

    Adjust the column position so that the septum contacts the bottom of the retaining nut. Use your fingers to tighten the retaining nut until it starts to grip the column. h. Tighten the column nut finger-tight until it starts to grip the column plus a quarter turn. Thermo Scientific ISQ 7000 Hardware Manual...
  • Page 62 80 °C (176 °F). Dans le cas contraire, il va fondre et endommager l’instrument. c. Repeat the leak check until no leaks are indicated. 5. Calibrate the carrier gas flow (column evaluation): ISQ 7000 Hardware Manual Thermo Scientific...
  • Page 63 Fix any issues found and rerun column evaluation until an appropriate K-factor is achieved.e a leak in the system, while a K-factor that is too high might indicate a blockage. 6. Disconnect the column flowmeter: Thermo Scientific ISQ 7000 Hardware Manual...
  • Page 64 Close the GC door. 7. If necessary, condition the column before inserting it into the ISQ 7000 system. Column conditioning consists of passing a carrier gas flow through the column heated to a programmed temperature as described in the column manufacturer’s instructions.
  • Page 65 Performing Routine Maintenance Replacing a Column ATTENTION DOMMAGES À L’INSTRUMENT : ne dépassez jamais la température de fonctionnement maximum de la colonne indiquée par le fabricant. Thermo Scientific ISQ 7000 Hardware Manual...

  • Page 66: Maintaining The Foreline Pump

    Always plug the foreline pump power cable into the System Mech Pump connector on the rear of the ISQ 7000 instrument and never into a wall outlet. This prevents the foreline pump from operating when the instrument is powered off.
  • Page 67 Performing Routine Maintenance Maintaining the Foreline Pump Figure 28. Connecting the ISQ 7000 Mass Spectrometer to the Foreline Pump System or Optional Mech Pump Connections Thermo Scientific ISQ 7000 Hardware Manual...

  • Page 68: Checking The Oil In The Foreline Pump

    CG pour éviter l’accumulation d’hydrogène dans le collecteur à vide. Reportez-vous aux « Précautions de sécurité relatives à l’hydrogène » à la page xvi de la préface pour plus d’informations. ISQ 7000 Hardware Manual Thermo Scientific...
  • Page 69 Performing Routine Maintenance Maintaining the Foreline Pump 3. Click Shut Down on the ISQ Dashboard or on the ISQ 7000 status page within the instrument software. 4. Click Yes to continue the shutdown process. The high voltages, heaters, and turbomolecular pump power off. Once the turbomolecular pump reaches 50% speed, or five minutes elapses, the foreline pump powers off and you may vent the system.
  • Page 70 16. If you are using hydrogen as a carrier gas, replace the front panel screw. 17. Replace all remaining hydrogen safety screws if you are using hydrogen. 18. Power on the ISQ 7000 mass spectrometer. ISQ 7000 Hardware Manual Thermo Scientific...

  • Page 71: Purging Gas From The Oil In The Foreline Pump

    To change the oil in the foreline pump: Note If you are running samples, stop the acquisition before powering off the system. 21. Cool down the GC oven. Thermo Scientific ISQ 7000 Hardware Manual...
  • Page 72 à vide. Reportez-vous aux « Précautions de sécurité relatives à l’hydrogène » à la page xvi de la préface pour plus d’informations. 23. Click Shut Down on the ISQ Dashboard or on the ISQ 7000 status page within the instrument software.
  • Page 73 Performing Routine Maintenance Maintaining the Foreline Pump Figure 30. Powering Off the ISQ 7000 Instrument Hydrogen Safety Screws Power Switch Vent Valve Knob Hydrogen Safety Screw Vacuum Interlock Shield (On Front Door Panel) 27. Open the front door of the instrument.
  • Page 74 AVERTISSEMENT RISQUE D’INCENDIE : utilisez uniquement de l’huile pour pompe préliminaire approuvée par le fabricant, afin d’éviter d’endommager l’instrument ou de provoquer un incendie. a. Add oil to the oil filler plug opening halfway between the MIN and MAX level marks. ISQ 7000 Hardware Manual Thermo Scientific...
  • Page 75 38. If you are using hydrogen as a carrier gas, replace the front panel screw. 39. Replace all remaining hydrogen safety screws if you are using hydrogen. 40. Power on the ISQ 7000 mass spectrometer. 41. If the GC is powered off, power it on and make sure vacuum compensation is on for the carrier gas flowing into the mass spectrometer.

  • Page 76: Cleaning The Ion Source Cartridge

    ISQ 7000 Mass Spectrometer with no VPI” page Removing the Extractabrite Ion Source Cartridge from the ISQ 7000 Mass Spectrometer with a VPI  To remove the ion source cartridge from the ISQ 7000 Mass Spectrometer with a VPI 1.
  • Page 77 After you reattach the knob, press the Evacuate button to eliminate any air inside the vacuum interlock. Thermo Scientific ISQ 7000 Hardware Manual...
  • Page 78 2. Get the source exchange tool out of the VPI MS Toolkit that shipped with your ISQ 7000 instrument. It is used to remove and insert the ion source cartridge through the vacuum interlock. The tool has a large black handle on one end and a stainless steel barrel at the other.
  • Page 79 Figure 33. Inserting the Ion Volume Tool Alignment b. Twist and push the barrel to the right until it clicks into place under the screw at the top of the slot. Figure 34. Twisting the Tool Into Place Alignment Thermo Scientific ISQ 7000 Hardware Manual...
  • Page 80 6. Loosen and twist the top part of the vacuum interlock handle to allow the entire handle to move up and down. This handle controls the interior ball valve, which seals the vacuum chamber and protects it from the outside pressure. ISQ 7000 Hardware Manual Thermo Scientific...
  • Page 81 Note If more than 60 seconds have passed since the Ready to Open light turned on, the Ready to Open light will turn off. You should press the Evacuate button and wait until the Ready to Open light is lit again. Thermo Scientific ISQ 7000 Hardware Manual...
  • Page 82 You are essentially disconnecting the ion source cartridge from the ion source block and moving it onto the tool. ISQ 7000 Hardware Manual Thermo Scientific...
  • Page 83 12. Once you reach the end of the track (when the back engraved line at the end of the barrel is exposed by the black handle), twist the handle to the left to lock it into place. Figure 39. Locking the Tool in Place Thermo Scientific ISQ 7000 Hardware Manual...
  • Page 84 14. Grasp the barrel of the tool and twist it to the left so that the alignment groove moves toward the left screw. Then pull the tool out of and away from the instrument. Figure 41. Removing the Tool from the Instrument ISQ 7000 Hardware Manual Thermo Scientific...
  • Page 85 Figure 42. Exposing the Ion Source Cartridge 17. Invert the ion source tool so that the barrel is pointed toward the floor. Figure 43. Inverting the Tool Ion Source Cartridge Thermo Scientific ISQ 7000 Hardware Manual...
  • Page 86 Source Holder 19. Twist the holder to disengage the ion source cartridge from the tool. 20. Set the ion source cartridge and holder on a clean surface. Figure 45. Removing the Ion Source Cartridge ISQ 7000 Hardware Manual Thermo Scientific...
  • Page 87 Figure 46. Ion Source Cartridge Components Lens 2 EI Ion Volume Ion Cartridge Sleeve Volume-Repeller Insulator Repeller Lens 3/RF Lens Spring Lens 1 Ion Volume Locking Ring Repeller Repeller 23. Set the components on a clean work surface. Thermo Scientific ISQ 7000 Hardware Manual...
  • Page 88  To remove the ion source cartridge from the ISQ 7000 mass spectrometer with no VPI 1. Click Shut Down on the ISQ 7000 Dashboard or on the ISQ status page within the instrument software. 2. Click Yes to continue the shutdown process. The high voltages, heaters, and turbomolecular pump power off.
  • Page 89 Note Remove the screws completely so that they do not scratch the manifold when you close the door. Figure 48. Removing the Manifold Door Screws 9. Open the manifold door. You can now see the ion source block. Thermo Scientific ISQ 7000 Hardware Manual...
  • Page 90 11. Twist the tool to the left. The ion source cartridge should now be connected to the small source removal tool. See Figure Figure 51. Twisting the Small Source Removal Tool 12. Slowly remove the ion source cartridge from the instrument. ISQ 7000 Hardware Manual Thermo Scientific...
  • Page 91 (which comes out in one piece), ion volume, lens 1, lens 2, and lens 3/RF lens. IMPORTANT Always wear clean, lint-free gloves when handling the ion source cartridge. Thermo Scientific ISQ 7000 Hardware Manual...

  • Page 92: Removing The Advanced Ion Source Cartridge On A Isq 7000 System

    Repeller 15. Set the components on a clean work surface. Removing the Advanced Ion Source Cartridge on a ISQ 7000 System 1. Click Shut Down on the TSQ Series Dashboard. Note You must shut down and vent the mass spectrometer even if your instrument has a vacuum interlock.
  • Page 93 Cleaning the Ion Source Cartridge 5. Twist the vent valve knob one and a half times in a counter-clockwise direction to open the vent. Figure 54. Venting the ISQ 7000 Mass Spectrometer Vent Valve Knob 6. Wait five minutes for venting to complete.
  • Page 94 10. Disconnect the filament wires from the source interface board. Figure 56. Disconnect the Filament Wires Filament Wires 11. Grasp the Vespel cap and gently remove the Advanced EI ion source from the ion source block. See Figure ISQ 7000 Hardware Manual Thermo Scientific...

  • Page 95: Cleaning The Ion Source Components

    GC oven to build up an oxidative layer before inserting the sleeve into the ion source block. An overly clean sleeve exterior surface can cause welding to the ion source block. 2. Clean the insulator, lens 1, and lens 3/RF lens according to Cleaning Delicate Components. Thermo Scientific ISQ 7000 Hardware Manual...

  • Page 96: Replacing The Ion Source Components

    2. Insert the ion cartridge sleeve into the source holder. Figure 59. Inserting the Sleeve into the Source Holder Note If you have an ISQ 7000 mass spectrometer with no VPI, you must order the source holder separately. See the ISQ and TSQ GC-MS Spare Parts Guide for ordering information.
  • Page 97 4. Place lens 2 on top of lens 3/RF lens with the small hole facing down. It should fit snugly and sit evenly on top of lens 3/RF lens. Figure 61. Inserting Lens 2 into the Source Sleeve Small Hole of Lens 2 Thermo Scientific ISQ 7000 Hardware Manual...
  • Page 98 Make sure the alignment tooth ion volume is firmly seated into the gap on lens 1. Figure 63. Inserting the Ion Volume into the Ion Cartridge Sleeve Alignment Tooth Notches Alignment Wings Lens 1 Gap ISQ 7000 Hardware Manual Thermo Scientific...
  • Page 99 Figure 64. Inserting the Repeller into the Ion Cartridge Sleeve Large Flat End of Repeller 8. Attach the repeller spring to the repeller. Figure 65. Inserting the Repeller Spring into the Ion Cartridge Sleeve Repeller Spring Thermo Scientific ISQ 7000 Hardware Manual...
  • Page 100 Figure 66. Inserting the Locking Ring into the Sleeve Larger Gaps on Locking Ring At this point the instructions vary with the model of ISQ 7000 mass spectrometer. To insert the ion source cartridge into the ISQ 7000 instrument with a VPI see “Replacing the Ion Source Cartridge in the ISQ 7000 with a VPI Instrument”...
  • Page 101 Using too much force when inserting the ion source cartridge into the barrel can cause damage. Thermo Scientific ISQ 7000 Hardware Manual...
  • Page 102 L’utilisation d’une force excessive lors de l’insertion de la cartouche de source d’ions dans le cylindre peut entraîner des dommages. Figure 68. Reattaching the Ion Source Cartridge to the Tool 5. Gently pull the source holder away from the ion source cartridge. Figure 69. Removing the Source Holder ISQ 7000 Hardware Manual Thermo Scientific...
  • Page 103 8. When the barrel can go no further, twist the handle to the right to lock it into position. 9. Insert the barrel end of the source exchange tool into the vacuum interlock and twist it to the right to lock it into position. Figure 70. Evacuating the Instrument Evacuate Button Thermo Scientific ISQ 7000 Hardware Manual...
  • Page 104 IMPORTANT Make sure you take the correct track on the tool or the ion volume will disassemble inside the instrument. If that happens, the tool will get stuck and you will have to shut down, vent the ISQ 7000 instrument, and manually remove the ion volume through the top of the instrument.
  • Page 105 Figure 72. Pulling the Tool Down the Right Track 15. Pull the vacuum interlock handle down to close the interior ball valve. Figure 73. Pulling Down the Vacuum Interlock Handle Thermo Scientific ISQ 7000 Hardware Manual...
  • Page 106 30 min for it to get to temperature, then remove and reinsert it. Replacing the Ion Source Cartridge in the ISQ 7000 Instrument with no VPI 1. Attach the ion source cartridge to the end of the small source removal tool as shown in Figure Note For correct insertion, the notch on the ion source cartridge must be facing up.
  • Page 107 3. Once the ion source cartridge is inserted into the ion source block, turn the small source tool to the right until you feel the ion source cartridge engage. 4. Remove the small source tool from the instrument. Thermo Scientific ISQ 7000 Hardware Manual...
  • Page 108 Figure 76. Removing the Small Source Tool from the Instrument 5. Be sure that the source interface board wires do not touch anything metal in the manifold before closing the door. Figure 77. Securing the Source Interface Board Wires ISQ 7000 Hardware Manual Thermo Scientific...
  • Page 109 6. Close the manifold door and slightly tighten the vent valve knob by turning it one half turn clockwise. 7. Flip the power switch on the back of the ISQ 7000 instrument upwards to power on the instrument. This will help you achieve good vacuum.

  • Page 110: Reassembling The Advanced Ei Ion Source Cartridge

    2. Insert the AEI ion volume with insulator into the Advanced EI ion source cartridge. Be sure that the opening for the column is exposed in the slot of the Advanced EI ion source cartridge. See Figure ISQ 7000 Hardware Manual Thermo Scientific...
  • Page 111 3. Insert the AEI filament shield into the AEI filament insulator. See Figure Figure 80. Preparing the AEI Filament Shield for Reassembly 4. Insert the AEI filament shield assembly into the AEI ion source cartridge. Rotational orientation does not matter. See Figure Thermo Scientific ISQ 7000 Hardware Manual...
  • Page 112 5. Add the filament to the Advanced EI ion source cartridge. The filament assembly will partially insert into the AEI filament insulator. The filament connection wires will protrude from the opposite side of the slot on the Advanced EI ion source cartridge. See Figure ISQ 7000 Hardware Manual Thermo Scientific...
  • Page 113 6. Align the filament spacer with the filament assembly. Be sure to align the notch on the filament spacer with the raised edge of the filament assembly. See Figure Figure 83. Aligning the Filament Spacer with the Filament Assembly Thermo Scientific ISQ 7000 Hardware Manual...
  • Page 114 8. Insert the ion source cartridge into the source block. See Figure Figure 85. Inserting the Advanced EI source into the Source Block 9. Reattach the filament wires to the source interface board. See Figure ISQ 7000 Hardware Manual Thermo Scientific...
  • Page 115 14. For optimal performance, wait at least fifteen minutes for the ion source to heat up to the same temperature as the inside of the instrument. Otherwise, the masses or intensities may be different. Thermo Scientific ISQ 7000 Hardware Manual...

  • Page 116: Maintaining The Calibration Gas Module

    Maintaining the Calibration Gas Module Maintaining the Calibration Gas Module The calibration gas module on the ISQ 7000 mass spectrometer is very easy to maintain because it is inside the front door of the instrument and you only have to refill the calibration gas reservoir every couple of years.

  • Page 117: Refilling The Calibrant Reservoir

    Refilling the Calibrant Reservoir  To refill the calibrant reservoir 1. Open the front door of the ISQ 7000 instrument. 2. Twist the calibrant reservoir cover counter-clockwise and remove it from the calibration gas module. Figure 87. Removing the Calibrant Reservoir Cover...
  • Page 118 5. Reattach the calibrant reservoir and cover to the calibration gas module. Note For information about replacing the calibrant reservoir, see Calibrant Reservoir Kit. Figure 89. Reattaching the Calibrant Reservoir Cover Calibration Gas Module Calibrant Reservoir Cover 6. Close the front door of the instrument. ISQ 7000 Hardware Manual Thermo Scientific...

  • Page 119: Replacing A Dual Filament

    WARNING FIRE HAZARD: If you are using hydrogen as a carrier gas, you must cool down and shut off the GC to prevent the buildup of hydrogen in the vacuum manifold. See the “Hydrogen Safety Precautions” page xvi of the Preface for more information. Thermo Scientific ISQ 7000 Hardware Manual...
  • Page 120 à vide. Reportez-vous aux « Précautions de sécurité relatives à l’hydrogène » à la page xvi de la préface pour plus d’informations. 3. Click Shut Down on the ISQ Dashboard or on the ISQ 7000 status page within the instrument software.
  • Page 121 12. Slide the top cover panel toward the back of the instrument and lift it off. 13. Remove the glass manifold cover from the top of the instrument. Figure 91. Removing the Glass Manifold Cover O-ring Manifold Door Glass Manifold Cover Thermo Scientific ISQ 7000 Hardware Manual...
  • Page 122 14. Use a T20 Torxhead screwdriver to remove the four screws around the manifold door. Figure 92. Opening the Manifold Door Screws 15. Open the front door to move the magnet yoke away from the filament. ISQ 7000 Hardware Manual Thermo Scientific...
  • Page 123 20. Insert the filament into its slot, rotate the spring into position, and slightly tighten the screw holding the filament retaining spring in place. Note Be sure the filament wires do not touch the source block or the manifold door when closed. Thermo Scientific ISQ 7000 Hardware Manual...
  • Page 124 à travers l’isolation s’ils entrent en contact avec une surface métallique. Soyez prudent lorsque vous fermez la porte, afin de vous assurer que les aimants n’entrent pas en contact avec le bloc source ou le dessus du filament. Cela peut les désengager du support. ISQ 7000 Hardware Manual Thermo Scientific...
  • Page 125 ATTENTION : assurez-vous que le couvercle du collecteur en verre recouvre complètement le joint torique afin que le collecteur soit correctement scellé. Le couvercle en verre ne doit pas dépasser la porte du collecteur. 23. Close the front door of the instrument. Thermo Scientific ISQ 7000 Hardware Manual...
  • Page 126 28. If you are using hydrogen as a carrier gas, replace the front panel screw. 29. Replace all remaining hydrogen safety screws if you are using hydrogen. 30. Power on the ISQ 7000 mass spectrometer. WARNING FIRE HAZARD: If you are using hydrogen, do NOT reach over the top of the instrument to power it on.

  • Page 127: Replacing The Electron Multiplier

    CG pour éviter l’accumulation d’hydrogène dans le collecteur à vide. Reportez-vous aux « Précautions de sécurité relatives à l’hydrogène » à la page xvi de la préface pour plus d’informations. Thermo Scientific ISQ 7000 Hardware Manual...
  • Page 128 ISQ 7000 instrument. 6. If you are using hydrogen as a carrier gas, unscrew the hydrogen safety screw on the front door. Figure 98. Powering Off the ISQ 7000 Instrument Hydrogen Safety Screws Power Switch Vent Valve...
  • Page 129 12. If you are using hydrogen, remove the remaining hydrogen safety screws. Note You must move the GC or MS to access the right hydrogen safety screw. 13. Slide the top cover panel toward the back of the instrument and lift it off. Thermo Scientific ISQ 7000 Hardware Manual...
  • Page 130 Performing Routine Maintenance Replacing the Electron Multiplier 14. Disconnect the electrometer board cable and large feedthrough cables. Figure 99. Disconnecting the Electron Multiplier Cables Electrometer Board Cable Large Electron Multiplier Plate ISQ 7000 Hardware Manual Thermo Scientific...
  • Page 131 CAUTION INSTRUMENT DAMAGE: Use clean, lint-free gloves when touching components inside the vacuum manifold. ATTENTION DOMMAGES À L’INSTRUMENT : utilisez des gants propres non pelucheux lorsque vous touchez des composants à l’intérieur du collecteur à vide. Thermo Scientific ISQ 7000 Hardware Manual...
  • Page 132 20. Make sure the electron multiplier fits snugly. 21. Reconnect the stainless steel wire to the gold connector. 22. Flip the electron multiplier and plate over and insert them into the instrument. ISQ 7000 Hardware Manual Thermo Scientific...
  • Page 133 24. Reconnect the electrometer board cable and large feedthrough cables. CAUTION INSTRUMENT DAMAGE: Do not mix up the cables or you will damage the power supply. ATTENTION DOMMAGES À L’INSTRUMENT : ne confondez pas les câbles ou vous endommagerez l’alimentation. Thermo Scientific ISQ 7000 Hardware Manual...
  • Page 134 Passez-la plutôt par le côté droit ou placez-vous derrière l’instrument et activez l’interrupteur d’alimentation. 32. On the ISQ Dashboard click Air & Water/Tune. 33. ISQ 7000 Manual Tune opens. Click Reset Multiplier. 34. Close ISQ 7000 Manual Tune. ISQ 7000 Hardware Manual...
  • Page 135 35. Allow sufficient time for the vacuum and temperatures to stabilize. 36. Go back to the ISQ Dashboard and click Auto Tune to open ISQ 7000 Autotune. 37. Run any tune that sets the gain of the electron multiplier to 3 x 10...

  • Page 136: Cleaning Durable Components

    Note You only need to clean the repeller, ion volume and all the lenses the most frequently. Cleaning the other components are not part of the expected maintenance. To clean durable components of the ISQ 7000 mass spectrometer, you will need the following cleaning supplies: •...
  • Page 137 Twist the sharpened end of the swab into the electron entrance hole on the CI ion volume to clean out debris. You may need to use several swabs before the electron entrance hole is clear of debris. Thermo Scientific ISQ 7000 Hardware Manual...
  • Page 138 Repeat until the water is clear. 5. Use forceps to immediately transfer the components to a clean beaker of acetone. ISQ 7000 Hardware Manual Thermo Scientific...
  • Page 139 Use forceps to transfer the components to a beaker of fresh acetone. c. Place the beaker and its contents in an ultrasonic bath for one minute. 7. Wearing gloves, blow clean, dry gas on the components to remove the acetone. Thermo Scientific ISQ 7000 Hardware Manual...

  • Page 140: Cleaning Delicate Components

    • Source magnets • Top (glass) manifold cover Note Cleaning these components are not part of the expected maintenance. To clean delicate components of the ISQ 7000 mass spectrometer, you will need the following cleaning supplies: • Applicators, cotton-tipped • Deionized water •...
  • Page 141 3. Rinse the components with methanol. Using forceps, dip the components in a beaker of methanol. Change the methanol if it becomes cloudy. Do not soak or sonicate the components. 4. Wearing gloves, use a clean, dry gas to blow the methanol off the components. Thermo Scientific ISQ 7000 Hardware Manual...

  • Page 142: Cleaning The Filters

    Cleaning the Filters Cleaning the Filters  To clean the filters on the ISQ 7000 instrument Note If your filters wear out or get damaged, see Replacing Fans and Filters information about replacing them. Optional dust filters are available. To order new filters, refer to the ISQ and TSQ GC-MS Spare Parts Guide.

  • Page 143: Troubleshooting

    Troubleshooting In this section, we describe the symptom and remedy for known issues with the ISQ 7000 mass spectrometer. All of these issues are related to hardware, but your instrument or software will alert you to them. For issues that you discover while reviewing your data, see the Troubleshooting section of the ISQ 7000 User Guide.

  • Page 144: Using Diagnostics

    Using Diagnostics Using Diagnostics If your ISQ 7000 instrument is running poorly or suspiciously, you can run software diagnostics to detect the problem and find a solution. Diagnostics tests electronic circuits and reports whether the circuits pass or fail. However, problems in sensitivity due to misalignment, dirty components, or improper tuning are not detected by the software.
  • Page 145 Copy. Figure 107. Copying a Tune Type 3. Name your diagnostic tune type. Figure 108. Naming Your Diagnostic Tune Type 4. Select the Diagnostics Only option in the Type field. Thermo Scientific ISQ 7000 Hardware Manual...
  • Page 146 5. Click the Diagnostics tab and select the types of diagnostics you would like to perform on your instrument. Figure 109. Selecting Types of Diagnostics 6. Click Save. 7. Click Close in the Tune Type editor dialog box. ISQ 7000 Hardware Manual Thermo Scientific...

  • Page 147: Running A Diagnostic Tune

    Troubleshooting Using Diagnostics Running a Diagnostic Tune  To run a diagnostic tune 1. Select AutoTune Options Advanced AutoTune on the ISQ 7000 Dashboard. Figure 110. Running an Automatic Tune Thermo Scientific ISQ 7000 Hardware Manual...
  • Page 148 2. The ISQ AutoTune dialog box opens. Select the diagnostics tune type you created and click Start. Figure 111. Running Diagnostics 3. To view the diagnostic results, click View Tune Report on the ISQ 7000Dashboard. ISQ 7000 Hardware Manual Thermo Scientific...
  • Page 149 Troubleshooting Using Diagnostics Figure 112. Viewing a Tune Report 4. Click the Report Options button in the upper right corner of the window. 5. Select Diagnostics in the Optional Reports area of the window. Thermo Scientific ISQ 7000 Hardware Manual...

  • Page 150: Investigating Communication Issues

    Possible Remedies Open the Instrument Configuration utility and verify the GC methods and configuration. Make sure the Remote Start cable is properly connected to the Generic/HS port on the GC and to the GC Start port on the ISQ 7000 instrument.
  • Page 151 Remote Start In: High to Low Inhibit Ready In: When High End of Run Out: High to Low Start of Run Out: High to Low GC Ready Out: When Low Prep Run Out: When Low Thermo Scientific ISQ 7000 Hardware Manual...

  • Page 152: Sample Data Are Not Acquired

    Make sure the Remote Start cable is properly connected to the GC. Make sure the End Run Time is set properly in the ISQ 7000 Instrument Setup file. Add more disk space to the computer by backing up and removing files.

  • Page 153: Investigating Contamination Issues

    Parts Guide for ordering information. WARNING ELECTRICAL SHOCK HAZARD: When troubleshooting any issue that requires removing a cover on the ISQ 7000 mass spectrometer, you should power-off and vent the instrument to avoid harming yourself. AVERTISSEMENT RISQUE D’ÉLECTROCUTION : lorsque vous cherchez à résoudre un problème nécessitant d’enlever le couvercle du spectromètre de masse ISQ 7000, mettez...

  • Page 154: Chemical Noise Is At M/Z 207, 429, 355, 281

    Chemical noise is at m/z 207, 429, 355, 281. Possible Remedies Condition the column. It is best to condition the column outside of the ISQ 7000 instrument so the contaminants can escape into the air instead of into the instrument.
  • Page 155 Investigating Contamination Issues Possible Remedies You may have a leak that is allowing solvent vapors to get into the ISQ 7000 instrument. Use a spray gas, such as Tetrafluoethane, to check for leaks and then fix them. See Investigating Vacuum Issues for details.

  • Page 156: Investigating Filament And Lens Control Issues

    Investigating Filament and Lens Control Issues Investigating Filament and Lens Control Issues Filament Check and Lens Check diagnostics can test the filament and lenses of the ISQ 7000 system. Handle the lenses with care. Damaged lenses may cause short circuits, which prevent the lens supplies from functioning properly.
  • Page 157 Make certain there are no large leaks. High pressure readings disable the lens voltages. Make certain the lever on the vacuum interlock is fully down. The lenses are disabled when the lever is in the up position. Thermo Scientific ISQ 7000 Hardware Manual...

  • Page 158: Investigating Temperature Issues

    The ion source and transfer line are heated zones in the ISQ 7000 mass spectrometer controlled by the lens driver PCB. Often, a temperature issue is the result of downloading a method to the ISQ 7000 system that has a different setpoint from the current setting, which causes a delay while the heated zone adjusts the temperature.

  • Page 159: Lens/Source Heater Will Not Heat

    Possible Remedies Make sure the ISQ 7000 system and the computer are properly connected. Confirm no fuses are blown on the lens driver PCB. If a fuse is blown, make sure no heater wires are shorted ground or each other before replacing the fuse.

  • Page 160: Transfer Line Overheats

    6 ohms and the resistance of the heater sensor is 50 to 300 ohms. If necessary, replace the transfer line. See Lens/Source Heater for details. Make sure the leads to the heaters and sensors are not electrically shorted to the tray. ISQ 7000 Hardware Manual Thermo Scientific...

  • Page 161: Investigating Vacuum Issues

    Your instrument or software may indicate the following types of issues. WARNING ELECTRICAL SHOCK HAZARD: When troubleshooting any issue that requires removing a cover on the ISQ 7000 mass spectrometer, you should power-off and vent the instrument to avoid harming yourself.

  • Page 162: An Air Leak Has Been Detected

    • Clean dust or debris from the top cover O-ring. If you do not find a leak, turn on the ISQ 7000 system in full-scan mode, open Manual Tune, select the real-time viewer and scan the mass range that covers the characteristic ions for the compressed gas you are using. Most compressed gases have ions between m/z 35 and 100.

  • Page 163: Turbomolecular Pump Shuts Off While In Use

    Power-off and vent the ISQ 7000 instrument. Let it cool to room temperature before powering it back on. Make sure all covers are in place on the ISQ 7000 instrument. The airflow necessary to cool the turbomolecular pump will be insufficient with the covers off.

  • Page 164: Investigating Power Supply Issues

    ±Q1 DC supply is outside the acceptable range. Possible Remedies Make sure the Rod Driver board is properly connected and use the Power Status tab on the ISQ 7000 Dashboard to ensure the readback reports +48 V DC is present.

  • Page 165: Investigating Rf/Dc Issues

    Possible Remedy Make sure the RF board is properly connected and use the Power Status tab on the ISQ 7000 Dashboard to ensure the readback reports +48 V DC is present. If +48 V DC is not present, contact Technical Support.

  • Page 166: Investigating Sensitivity Issues

    WARNING ELECTRICAL SHOCK HAZARD: When troubleshooting any issue that requires removing a cover on the ISQ 7000 mass spectrometer, you should power-off and vent the instrument to avoid harming yourself. AVERTISSEMENT RISQUE D’ÉLECTROCUTION : lorsque vous cherchez à résoudre un problème nécessitant d’enlever le couvercle du spectromètre de masse ISQ 7000, mettez...

  • Page 167: Poor Sensitivity Or Sudden Loss In Sensitivity

    Perform a daily tune check to determine if you are getting the correct response to the calibration gas. Verify the leak check is below 7%. If the calibration gas sensitivity is low, switch to the second filament and tune the ISQ 7000 instrument to determine if the calibration gas sensitivity is recovered.
  • Page 168 Otherwise, you may damage the filament. An increase in signal for the calibration gas as you push on the ion volume usually indicates that the filament is not aligned properly. ISQ 7000 Hardware Manual Thermo Scientific...

  • Page 169: Investigating Stability Issues

    WARNING ELECTRICAL SHOCK HAZARD: When troubleshooting any issue that requires removing a cover on the ISQ 7000 mass spectrometer, you should power-off and vent the instrument to avoid harming yourself. AVERTISSEMENT RISQUE D’ÉLECTROCUTION : lorsque vous cherchez à résoudre un problème nécessitant d’enlever le couvercle du spectromètre de masse ISQ 7000, mettez...

  • Page 170: Investigating Tuning Issues

    WARNING ELECTRICAL SHOCK HAZARD: When troubleshooting any issue that requires removing a cover on the ISQ 7000 mass spectrometer, you should power-off and vent the instrument to avoid harming yourself.

  • Page 171: Tune Is Interrupted

    & Water /Tune from the ISQ 7000 Dashboard to launch ISQ Manual Tune. Create a starting tune file using manual tune. Select Air & Water /Tune from the ISQ 7000 Dashboard to launch ISQ Manual Tune. Confirm that the correct ion volume is installed in the instrument. For example, a CI ion volume may cause an EI tune to fail.

  • Page 172: Cannot Perform Mass Calibration

    Allow contaminants to pump away so they do not interfere with calibration gas ions. Create a starting tune file using manual tune. Select Air & Water /Tune from the ISQ 7000 Dashboard to launch ISQ Manual Tune An air leak has been detected.

  • Page 173: Contacting Technical Support

    Support. Be sure to reference the model number and serial number of your instrument when contacting them. Every ISQ 7000 mass spectrometer ships with a label inside the front door that lists the model number and serial number. Figure 113. Identifying Your Instrument...
  • Page 174 Troubleshooting Contacting Technical Support ISQ 7000 Hardware Manual Thermo Scientific...

  • Page 175: Advanced Maintenance

    Advanced Maintenance This chapter describes ISQ 7000 system components that do not require routine maintenance, but troubleshooting may indicate they need to be replaced. Components are listed according to the likelihood (high to low) that they will need to be replaced before the end of the instrument’s life.

  • Page 176: Replacing Components Of The Analyzer

    All of the components of the analyzer are on a sliding tray. There are three main components: the ion source, ion guide, and Q1 assembly. Figure 114. Replaceable Components of the Analyzer Tray Q1 Assembly Analyzer Tray Ion Guide Ion Source ISQ 7000 Hardware Manual Thermo Scientific...

  • Page 177: Analyzer Tray

    This section provides instructions for replacing the analyzer tray. The analyzer tray itself is unlikely to fail, but you must follow these steps anytime you remove the analyzer tray from the ISQ 7000 mass spectrometer to service or replace other components. WARNING - INSTRUMENT DAMAGE Thermo Fisher Scientific strongly recommends that only trained Thermo Fisher Scientific Field Service Engineers remove the analyzer tray and service its components.
  • Page 178 à vide. Reportez-vous aux « Précautions de sécurité relatives à l’hydrogène » à la page xvi de la préface pour plus d’informations. 4. Click Shut Down on the ISQ 7000 Dashboard or on the ISQ 7000 status page within the instrument software.
  • Page 179 9. Look behind the right side of the vacuum interlock shield and twist the vent valve knob one and a half times in a counter-clockwise direction to open the vent. Note If you have a ISQ 7000 system with no VPI, the vent valve knob is in the same location as shown in Figure 115.
  • Page 180 Electron Multiplier Plate 3. Use a T20 Torxhead screwdriver to remove the four screws at each corner of the electron multiplier plate. Figure 117. Disconnecting the Electron Multiplier Plate Electron Multiplier Plate Screws Groove ISQ 7000 Hardware Manual Thermo Scientific...
  • Page 181 Figure 118. Opening the Manifold Door Screws 6. Open the manifold door. 7. Remove the glass manifold cover from the top of the instrument and set it on a surface where it will not be scratched or contaminated. Thermo Scientific ISQ 7000 Hardware Manual...
  • Page 182 Figure 120. Removing the Right Side Panel 13. Identify the set screw on the source heater block. This T10 screw holds the transfer line in alignment with the ion volume heater block. See Figure 121. ISQ 7000 Hardware Manual Thermo Scientific...
  • Page 183 Place this screw in a clean place until it is needed for reassembly. See Figure 122. Figure 122. Removing the Set Screw Source Interface Board Screw Calibration and Reagent Gas Tubes Right Screw Thermo Scientific ISQ 7000 Hardware Manual...
  • Page 184 Be careful to not use excessive force so that the transfer line tip and source heater block are not damaged. Be sure not to bend the tubes or scratch the transferline. ISQ 7000 Hardware Manual Thermo Scientific...
  • Page 185 21. Remove the heat shield and wedge it between the source interface board and the wall of the manifold to disconnect the board from the 20-pin feedthrough. 22. Remove the bottom right screw holding the tray to the manifold. Thermo Scientific ISQ 7000 Hardware Manual...
  • Page 186 Figure 126. Sliding the Analyzer Tray Out of the Instrument Analyzer Tray 24. Set the tray on a clean work surface. ISQ 7000 Hardware Manual Thermo Scientific...
  • Page 187 Note Make sure you set the rods on a clean, lint-free cloth. Dust and lint on the rods lead to poor analytical performance. 4. Use a T10 Torxhead screwdriver to remove the lens heater block grounding strap screw from the analyzer tray. Thermo Scientific ISQ 7000 Hardware Manual...
  • Page 188 Block Screws Grounding Strap 6. Remove the ion source from the analyzer tray and set it aside. 7. Replace the analyzer tray with a new one if needed. Figure 129. Replacing the Analyzer Tray ISQ 7000 Hardware Manual Thermo Scientific...
  • Page 189 4. Slide the ion guide and endcap back into the analyzer tray. Figure 131. Rejoining the Ion Guide to the Quadrupole Ion Guide Q1 Quad Assembly 5. Insert the quadrupole assembly with exit endcap onto the analyzer tray. Thermo Scientific ISQ 7000 Hardware Manual...
  • Page 190 Do not screw in the analyzer tray until the transfer line is fully screwed in. Note The analyzer tray will mount on one alignment pin in the back and the transfer line on the right. The mixing chamber will rest on the transfer line when installed. ISQ 7000 Hardware Manual Thermo Scientific...
  • Page 191 Fully screw in screws holding the transfer line to the manifold, compressing the o-ring until the transfer line flange metal touches the metal of the manifold. Thermo Scientific ISQ 7000 Hardware Manual...
  • Page 192 8. Reattach the filament board and wires. 9. Check all wires to ensure that none contact any metal surface and that there is sufficient space left below the source block for the magnet yoke. ISQ 7000 Hardware Manual Thermo Scientific...
  • Page 193 4. Reinsert the column to the proper length and tighten the transfer line nut. 5. If you are using hydrogen as a carrier gas, replace the front panel screw. 6. Replace the ion source cartridge. Replace all remaining hydrogen safety screws if you are using hydrogen. Thermo Scientific ISQ 7000 Hardware Manual...
  • Page 194 Advanced Maintenance Replacing Components of the Analyzer 7. Power on the ISQ 7000 mass spectrometer. 8. If the GC is powered off, power it on and make sure vacuum compensation is on for the carrier gas flowing into the mass spectrometer.

  • Page 195: Ion Guide

    “Shutting Down the ISQ 7000 System” page 149. 2. Remove the analyzer tray from the instrument by following the instructions in “Removing the Analyzer Tray from the ISQ 7000 Instrument” page 151. 3. Remove the ion source cartridge according to “Ion Source Cartridge”...
  • Page 196 12. Slide the ion guide and entrance endcap back onto the rods and exit endcap. 13. Reattach the ion guide and quadrupole to the analyzer tray. Make sure the quad and ion guide and fully forward before tightening screws. ISQ 7000 Hardware Manual Thermo Scientific...
  • Page 197 16. Once the components are correctly attached to the analyzer tray, follow the instructions “Replacing the Analyzer Tray” page 162. 17. Restart your system by following the instructions in “Restarting the System” page 165. Thermo Scientific ISQ 7000 Hardware Manual...

  • Page 198: Ion Guide Clamp

    149. 2. Remove the analyzer tray from the instrument by following the instructions in “Removing the Analyzer Tray from the ISQ 7000 Instrument” page 151. 3. Remove the wire connecting the quadrupole entrance lens to the source interface board by unscrewing the terminal with a slotted screwdriver.

  • Page 199: Attach The Wire Connecting The Quadrupole Entrance Lens To The Source Interface Board By Screwing In The Terminal With A Slotted Screwdriver

    13. Once the components are correctly attached to the analyzer tray, follow the instructions “Replacing the Analyzer Tray” page 162. 14. Restart your system by following the instructions in “Restarting the System” page 165. Thermo Scientific ISQ 7000 Hardware Manual...

  • Page 200: Ion Guide Wire Set

    149. 2. Remove the analyzer tray from the instrument by following the instructions in “Removing the Analyzer Tray from the ISQ 7000 Instrument” page 151. 3. Use a T10 Torxhead screwdriver to remove the screw connecting the ion guide wire to the top of the ion guide.

  • Page 201: Quadrupole

    “Shutting Down the ISQ 7000 System” page 149. 2. Remove the analyzer tray from the instrument by following the instructions in “Removing the Analyzer Tray from the ISQ 7000 Instrument” page 151. 3. Remove the screws from the exit endcap.
  • Page 202 11. Once the components are correctly attached to the analyzer tray, follow the instructions “Replacing the Analyzer Tray” page 162. 12. Restart your system by following the instructions in “Restarting the System” page 165. ISQ 7000 Hardware Manual Thermo Scientific...

  • Page 203: Quadrupole Wire Set

    “Shutting Down the ISQ 7000 System” page 149. 2. Remove the analyzer tray from the instrument by following the instructions in “Removing the Analyzer Tray from the ISQ 7000 Instrument” page 151. 3. Remove the screws from each side of the exit endcap.
  • Page 204 Ces vis peuvent se gripper dans les barres. 8. Attach new wires to each side of the rods. 9. Slide the quadrupole rods back into the analyzer tray. ISQ 7000 Hardware Manual Thermo Scientific...

  • Page 205: Once The Components Are Correctly Attached To The Analyzer Tray, Follow The Instructions In "Replacing The Analyzer Tray" On Page

    11. Once the components are correctly attached to the analyzer tray, follow the instructions “Replacing the Analyzer Tray” page 162. 12. Restart your system by following the instructions in “Restarting the System” page 165. Thermo Scientific ISQ 7000 Hardware Manual...

  • Page 206: Quadrupole Entrance Lens

    149. 2. Remove the analyzer tray from the instrument by following the instructions in “Removing the Analyzer Tray from the ISQ 7000 Instrument” page 151. 3. Remove the wire connecting the quadrupole entrance lens to the source interface board by unscrewing the terminal with a slotted screwdriver.
  • Page 207 11. Reattach the two screws holding the quad entrance lens to the ion guide clamp. 12. Slide the rods and exit endcap back onto the ion guide and entrance endcap. Figure 153. Rejoining the Ion Guide to the Quadrupole Quadrupole Rods Ion Guide Thermo Scientific ISQ 7000 Hardware Manual...
  • Page 208 15. Once the components are correctly attached to the analyzer tray, follow the instructions “Replacing the Analyzer Tray” page 162. 16. Restart your system by following the instructions in “Restarting the System” page 165 ISQ 7000 Hardware Manual Thermo Scientific...

  • Page 209: Exit Endcap

    149. 2. Remove the analyzer tray from the instrument by following the instructions in “Removing the Analyzer Tray from the ISQ 7000 Instrument” page 151. 3. Remove the two screws on each side of the exit endcap and slide it off the back of the tray.

  • Page 210: Entrance Endcap

    149. 2. Remove the analyzer tray from the instrument by following the instructions in “Removing the Analyzer Tray from the ISQ 7000 Instrument” page 151. 3. Remove the wire connecting the quadrupole entrance lens to the source interface board by unscrewing the terminal with a slotted screwdriver.
  • Page 211 12. Use a T10 Torxhead screwdriver to attach the screws holding the ion guide to the ion guide clamp. Figure 160. Reattaching the Ion Guide to the Ion Guide Clamp Ion Guide Clamp Screws Ion Guide Thermo Scientific ISQ 7000 Hardware Manual...
  • Page 212 15. Attach the wire connecting the quadrupole entrance lens to the source interface board by screwing in the terminal with a slotted screwdriver. 16. Follow the instructions in “Replacing the Analyzer Tray” page 162. 17. Restart your system by following the instructions in “Restarting the System” page 165. ISQ 7000 Hardware Manual Thermo Scientific...

  • Page 213: Replacing Components Of The Ion Source

    Ion Volume-Repeller Insulator Thumbscrew-Repeller Spacers Insulating Spacers NOTE: You can also replace the entire ion source cartridge, which consists of the locking ring, spring, nut, repeller, lenses, and sleeve. Ion Source Cartridge for details. Thermo Scientific ISQ 7000 Hardware Manual...

  • Page 214: Ion Source Block

    149. 2. Remove the analyzer tray from the instrument by following the instructions in “Removing the Analyzer Tray from the ISQ 7000 Instrument” page 151. 3. Use a T10 Torxhead screwdriver to disconnect the lens heater block grounding strap from the lens heater block, but leave it attached to the tray.
  • Page 215 5. Slide the source interface board and ion source out from under the tray without damaging or disconnecting the wires. Figure 165. Removing the Ion Source from the Analyzer Tray Wires 6. Set the source interface board on its side. Thermo Scientific ISQ 7000 Hardware Manual...
  • Page 216 Replacing Components of the Ion Source 7. Twist and remove the two source-repeller thumbscrews. Figure 166. Removing the Source-Repeller Thumbscrews Source-Repeller Thumbscrews 8. Remove the thumbscrew-repeller spacers and set them aside. Figure 167. Removing the Thumbscrew-Repeller Spacers Thumbscrew-Repeller Spacers ISQ 7000 Hardware Manual Thermo Scientific...
  • Page 217 11. Use a T20 Torxhead screwdriver to remove the two screws connecting the lens/source heater to the ion source block. Figure 169. Disconnecting the Lens/Source Heater Lens/Source Heater Screws Thermo Scientific ISQ 7000 Hardware Manual...
  • Page 218 13. Reattach the lens/source heater to the new ion source block and set them next to the rest of the ion source. Figure 171. Reattaching the Lens/Source Heater Lens/Source Heater Screws 14. Reattach the repeller plate and insulating spacers. ISQ 7000 Hardware Manual Thermo Scientific...
  • Page 219 16. Attach the source-repeller thumbscrews to the endcaps and twist them back on. When you are tightening the thumbscrews, make sure the spacers stay in the groove or you could crush them. Figure 173. Reattaching the Source-Repeller Thumbscrews Source-Repeller Thumbscrews Thermo Scientific ISQ 7000 Hardware Manual...
  • Page 220 18. Reattach the two screws to the back of the ion source. Figure 175. Reconnecting the Ion Source to the Analyzer Tray Screws ISQ 7000 Hardware Manual Thermo Scientific...
  • Page 221 20. Once the components are correctly attached to the analyzer tray, follow the instructions “Replacing the Analyzer Tray” page 162. 21. Restart your system by following the instructions in “Restarting the System” page 165. Thermo Scientific ISQ 7000 Hardware Manual...

  • Page 222: Source-Repeller Thumbscrews

    Note See the ISQ and TSQ GC-MS Spare Parts Guide for information about ordering this component. 1. Shut down your system by following the steps in “Shutting Down the ISQ 7000 System” page 149. 2. Use a T20 Torxhead screwdriver to remove the four screws around the manifold door.
  • Page 223 Replacing Components of the Ion Source 4. Attach new source-repeller thumbscrews to the ion source. 5. Reattach the manifold door and the four screws. 6. Restart your system by following the instructions in “Restarting the System” page 165. Thermo Scientific ISQ 7000 Hardware Manual...

  • Page 224: Thumbscrew-Repeller Spacers

    Note See the ISQ and TSQ GC-MS Spare Parts Guide for information about ordering this component. 1. Shut down your system by following the steps in “Shutting Down the ISQ 7000 System” page 149. 2. Use a T20 Torxhead screwdriver to remove the four screws around the manifold door.
  • Page 225 Also, do not over-tighten the thumbscrews or it may crush the spacers. 5. Reattach the source-repeller thumbscrews to the spacers. 6. Reattach the front manifold door and four screws. 7. Restart your system by following the instructions in “Restarting the System” page 165. Thermo Scientific ISQ 7000 Hardware Manual...

  • Page 226: Insulating Spacers

    Note See the ISQ and TSQ GC-MS Spare Parts Guide for information about ordering this component. 1. Shut down your system by following the steps in “Shutting Down the ISQ 7000 System” page 149. 2. Use a T20 Torxhead screwdriver to remove the four screws around the manifold door.
  • Page 227 Thumbscrew-Repeller Spacers 5. Move the locking ring out of the way. 6. Remove and replace the insulating spacers. Figure 185. Replacing the Insulating Spacers Insulating Spacers 7. Move the locking ring back into place. Thermo Scientific ISQ 7000 Hardware Manual...
  • Page 228 Also, do not over-tighten the thumbscrews or it may crush the spacers. 9. Reattach the source-repeller thumbscrews. 10. Reattach the manifold door and the four screws. 11. Restart your system by following the instructions in “Restarting the System” page 165. ISQ 7000 Hardware Manual Thermo Scientific...

  • Page 229: Repeller Plate

    “Shutting Down the ISQ 7000 System” page 149. 2. Remove the analyzer tray from the instrument by following the instructions in “Removing the Analyzer Tray from the ISQ 7000 Instrument” page 151. 3. Twist off the source-repeller thumbscrews. Figure 186. Removing the Source-Repeller Thumbscrews...
  • Page 230 11. Reattach the thumbscrew-repeller spacers. Note When reattaching the spacers, make sure they fit into the grooves on the thumbscrews. Also, do not over-tighten the thumbscrews or it may crush the spacers. 12. Reattach the source-repeller thumbscrews ISQ 7000 Hardware Manual Thermo Scientific...
  • Page 231 14. Once the components are correctly attached to the analyzer tray, follow the instructions “Replacing the Analyzer Tray” page 162. 15. Restart your system by following the instructions in “Restarting the System” page 165. Thermo Scientific ISQ 7000 Hardware Manual...

  • Page 232: Lens/Source Heater

    149. 2. Remove the analyzer tray from the instrument by following the instructions in “Removing the Analyzer Tray from the ISQ 7000 Instrument” page 151. 3. Lay the source interface board on its side. Remove the four wires connecting the heater and RTD to the board with a slotted screwdriver.
  • Page 233 Advanced Maintenance Replacing Components of the Ion Source 9. Restart your system by following the instructions in “Restarting the System” page 165. Thermo Scientific ISQ 7000 Hardware Manual...

  • Page 234: Lens Heater Block

    149. 2. Remove the analyzer tray from the instrument by following the instructions in “Removing the Analyzer Tray from the ISQ 7000 Instrument” page 151. 3. Use a T10 Torxhead screwdriver to disconnect the lens heater block grounding strap from the lens heater block, but leave it attached to the tray.
  • Page 235 5. Slide the source interface board and ion source out from under the tray without damaging or disconnecting the wires. Figure 193. Sliding the Ion Source Off the Analyzer Tray Wires 6. Set the source interface board on its side. Thermo Scientific ISQ 7000 Hardware Manual...
  • Page 236 11. Attach the lens heater to the new lens heater block. 12. Slide the source interface board and ion source onto the tray without damaging or disconnecting the wires. Figure 195. Sliding the Ion Source onto the Analyzer Tray Wires ISQ 7000 Hardware Manual Thermo Scientific...
  • Page 237 15. Once the components are correctly attached to the analyzer tray, follow the instructions “Replacing the Analyzer Tray” page 162. 16. Restart your system by following the instructions in “Restarting the System” page 165. Thermo Scientific ISQ 7000 Hardware Manual...

  • Page 238: Lens Heater Block Grounding Strap

    149. 2. Remove the analyzer tray from the instrument by following the instructions in “Removing the Analyzer Tray from the ISQ 7000 Instrument” page 151. 3. Use a T10 Torxhead screwdriver to disconnect the screws holding the lens heater block grounding strap to the lens heater block and analyzer tray.

  • Page 239: Lens Plate And Springs

    149. 2. Remove the analyzer tray from the instrument by following the instructions in “Removing the Analyzer Tray from the ISQ 7000 Instrument” page 151. 3. Disconnect the lens wires form the source interface board with a slotted screwdriver.

  • Page 240: Source To Ion Guide Spacer

    149. 2. Remove the analyzer tray from the instrument by following the instructions in “Removing the Analyzer Tray from the ISQ 7000 Instrument” page 151. 3. Use a T10 Torxhead screwdriver to disconnect the lens heater block grounding strap from the lens heater block, but leave it attached to the tray Figure 200.
  • Page 241 Figure 201. Disconnecting the Ion Source from the Analyzer Tray Screws 5. Slide the source interface board and ion source out from under the tray without damaging or disconnecting the wires. Figure 202. Removing the Ion Source from the Analyzer Tray Wires Thermo Scientific ISQ 7000 Hardware Manual...
  • Page 242 Source to Ion Guide Spacer 7. Slide the source interface board and ion source back onto the tray without damaging or disconnecting the wires. Figure 204. Sliding the Ion Source Onto the Analyzer Tray Wires ISQ 7000 Hardware Manual Thermo Scientific...
  • Page 243 10. Once the components are correctly attached to the analyzer tray, follow the instructions “Replacing the Analyzer Tray” page 162. 11. Restart your system by following the instructions in “Restarting the System” page 165. Thermo Scientific ISQ 7000 Hardware Manual...

  • Page 244: Ion Source Cartridge

    Figure 207. Replaceable Components of the Ion Source Cartridge Lens 2 EI Ion Volume Ion Cartridge Sleeve Lens 3/RF Lens Repeller Repeller Spring Lens 1 Ion Volume Locking Ring Ion Volume-Repeller Insulator Repeller ISQ 7000 Hardware Manual Thermo Scientific...
  • Page 245  To replace components of the Advanced EI ion source cartridge 1. Follow the procedure in “Removing the Advanced Ion Source Cartridge on a ISQ 7000 System” page 64 to remove the ion source cartridge. 2. Replace the components as necessary 3.

  • Page 246: Replacing Components Of The Source Exchange Tool

    Note See the ISQ and TSQ GC-MS Spare Parts Guide for information about ordering this component. Figure 209. Replaceable Components of the Source Exchange Tool Seal Clip Bushing ISQ 7000 Hardware Manual Thermo Scientific...
  • Page 247 Figure 211. Removing the Endcap Set Screw Endcap 6. Slide the handle off the rest of the tool. Set it aside. 7. Remove the interior shaft from the barrel. Figure 212. Removing the Interior Shaft Interior Shaft Barrel Thermo Scientific ISQ 7000 Hardware Manual...
  • Page 248 Replace the seal, if necessary. 11. Insert the flared end of the seal into the end of the barrel. Figure 214. Inserting the Seal Flared End of Seal Bushing Barrel ISQ 7000 Hardware Manual Thermo Scientific...
  • Page 249 20. Tighten the set screw. Note The purpose of the set screw is to keep the components together. Don’t overtighten it or the handle will be hard to slide up and down the barrel. Thermo Scientific ISQ 7000 Hardware Manual...

  • Page 250: Replacing Components Of The Vacuum Interlock

    Vacuum Interlock Knob (Valve body is shown for illustration purposes Spring only. It is not available for purchase.) Valve Axle O-Ring Axle Seal Clip Axle Bearing O-Ring Inner Ball Seal Sealing Ball Outer Ball Seal ISQ 7000 Hardware Manual Thermo Scientific...

  • Page 251: Shut Down Your System By Following The Steps In On Page

     To replace the components of the vacuum interlock 1. Shut down your system by following the steps in “Shutting Down the ISQ 7000 System” page 149. Note You do not have to remove the ion source cartridge or the column. However, you must vent the instrument.
  • Page 252 4. Pinch together the two springs on the left side the vacuum interlock shield and remove it. Figure 221. Removing the Vacuum Interlock Shield Springs 5. Lift the vacuum interlock shield off the instrument. The notch at the bottom of the track will go around the handle. ISQ 7000 Hardware Manual Thermo Scientific...
  • Page 253 Figure 222. Detaching the Manifold Door Screws 7. Set the manifold door on a clean work surface and remove the two screws holding the pillow block in place. Figure 223. Removing the Pillow Block Pillow Block Screws Thermo Scientific ISQ 7000 Hardware Manual...
  • Page 254 Screws 9. Detach the valve body and its components from the front manifold plate. Figure 225. Detaching the Valve Body from the Front Manifold Plate Vacuum Interlock Handle Shaft Valve Axle Screws Pillow Block ISQ 7000 Hardware Manual Thermo Scientific...
  • Page 255 Tip It may be easier to remove the sealing ball if you push on it from the front, but be careful not to scratch the ball. 14. Remove the o-ring and replace it, if necessary. Thermo Scientific ISQ 7000 Hardware Manual...
  • Page 256 Figure 227. Replacing the Sealing Ball and Outer Ball Seal Sealing Ball Outer Ball Seal 16. Pry the thin metal clip out of the groove. It holds all of the other components inside the valve body. Figure 228. Replacing the Metal Clip Clip ISQ 7000 Hardware Manual Thermo Scientific...
  • Page 257 18. Push the valve axle into the side of the valve body. Replace the valve axle, if necessary. 19. Remove the brown axle seal from the valve body. Replace the axle seal, if necessary and then insert it into the valve body. Figure 230. Replacing the Axle Seal Axle Seal Thermo Scientific ISQ 7000 Hardware Manual...
  • Page 258 Figure 231. Reinserting the Valve Axle and Inner Ball Seal Inner Ball Seal Valve Axle 21. Reinsert the axle bearing into the valve body. 22. Press and twist the thin metal clip into the top groove. Figure 232. Reinserting the Clip Clip ISQ 7000 Hardware Manual Thermo Scientific...
  • Page 259 25. Insert the inner ball seal into the valve body. 26. Reattach the small spring and safety interlock to the valve body. Figure 234. Reattaching the Spring and Safety Interlock to the Valve Body Safety Interlock Spring Thermo Scientific ISQ 7000 Hardware Manual...
  • Page 260 Figure 235. Reattaching the Vacuum Interlock Handle to the Valve Body Vacuum Interlock Handle Shaft Valve Axle Screws Pillow Block 28. Slide the pillow block over and onto the end of the valve axle. ISQ 7000 Hardware Manual Thermo Scientific...
  • Page 261 CAUTION INSTRUMENT DAMAGE: If the vacuum interlock handle is not fully down and the ball valve is not fully closed, then the ball valve may not be able to completely open it during use and it could damage the ball valve and probes. Thermo Scientific ISQ 7000 Hardware Manual...
  • Page 262 à tournant sphérique ne puisse pas s’ouvrir complètement lors de l’utilisation, ce qui peut endommager le robinet à tournant sphérique et les sondes. 31. Reattach the manifold door and the four screws. Figure 238. Reattaching the Manifold Door Screws ISQ 7000 Hardware Manual Thermo Scientific...
  • Page 263 32. Hold the spring and safety interlock in place as you attach the vacuum interlock shield and screws. Figure 239. Reattaching the Vacuum Interlock Shield Screws Vacuum Interlock Shield 33. Reattach the vacuum interlock knob. Thermo Scientific ISQ 7000 Hardware Manual...

  • Page 264: On Page

    34. Reconnect the vacuum interlock cable from the connector. Figure 240. Reconnecting the Vacuum Interlock Cable Vacuum Interlock Cable Connector 35. Restart your system by following the instructions in “Restarting the System” page 165. ISQ 7000 Hardware Manual Thermo Scientific...

  • Page 265: Replacing Components Of The Manifold

    Figure 241. Replaceable Components of the Manifold Back Front Door Plate Alignment Pins Manifold O-ring Manifold Door Hinge Vent Valve Knob and O-Ring Alignment Pin Source Magnets Manifold O-ring Source Magnet Front Plate Insertion Yoke Guide Thermo Scientific ISQ 7000 Hardware Manual...

  • Page 266: Manifold Door Hinge

    Note See the ISQ and TSQ GC-MS Spare Parts Guide for information about ordering this component. 1. Shut down your system by following the steps in “Shutting Down the ISQ 7000 System” page 149. Note You do not have to remove the ion source cartridge or the column. However, you must vent the instrument.
  • Page 267 5. Use your fingers to pry the bracket of the board away from the chassis and toward the left side of the instrument. 6. Use a T20 Torxhead screwdriver to remove the four screws around the manifold door. Figure 244. Opening the Manifold Door Screws Thermo Scientific ISQ 7000 Hardware Manual...
  • Page 268 8. Look through the left side of the instrument and use a T20 Torxhead screwdriver to remove the three screws connecting the hinge to the chassis. Figure 246. Replacing the Manifold Door Hinge Screws Hinge ISQ 7000 Hardware Manual Thermo Scientific...
  • Page 269 12. Align the connector on the bottom of the lens driver board with the connectors on the distribution board beneath it. It will drop into the connector when its in the right position. Figure 248. Reinstalling the Lens Driver Board Connector Thermo Scientific ISQ 7000 Hardware Manual...
  • Page 270 Figure 249. Reattaching the Lens Driver Board Lens Driver Board Screw 14. Reattach the top cover and left side panels and tighten the screws. 15. Restart your system by following the instructions in “Restarting the System” page 165. ISQ 7000 Hardware Manual Thermo Scientific...

  • Page 271: Front Manifold Plate

    Note See the ISQ and TSQ GC-MS Spare Parts Guide for information about ordering this component. 1. Shut down your system by following the steps in “Shutting Down the ISQ 7000 System” page 149. Note You do not have to remove the ion source cartridge or column. However, you must vent the instrument.
  • Page 272 Figure 251. Disconnecting the Vacuum Interlock Cable Tubing Vacuum Interlock Cable Connector 4. Pinch together the two springs on the left side the vacuum interlock shield to remove it. Figure 252. Removing the Vacuum Interlock Shield Vacuum Interlock Shield Springs ISQ 7000 Hardware Manual Thermo Scientific...
  • Page 273 6. Remove the two screws connecting the pillow block to the front manifold plate. 7. Remove the three screws holding the valve body to the front manifold plate. Figure 254. Disconnecting the Valve Body Valve Front Body Manifold Plate Screws Thermo Scientific ISQ 7000 Hardware Manual...
  • Page 274 10. Twist and remove the front door alignment pins that hold the magnet yoke to the back of the manifold door. Figure 256. Removing the Front Door Alignment Pins Magnet Yoke Front Door Alignment Pins ISQ 7000 Hardware Manual Thermo Scientific...
  • Page 275 15. Reattach the front plate o-ring. • Flip the manifold door over and reattach the magnet yoke, source magnets, and source retainer magnets. 16. Reattach the three screws and valve body to the front manifold plate. Thermo Scientific ISQ 7000 Hardware Manual...
  • Page 276 18. Hold the spring and safety interlock in place as you attach the vacuum interlock shield and screws. 19. Reconnect the vacuum interlock cable and tubing. 20. Restart your system by following the instructions in “Restarting the System” page 165. ISQ 7000 Hardware Manual Thermo Scientific...

  • Page 277: Back Manifold Plate

    Note See the ISQ and TSQ GC-MS Spare Parts Guide for information about ordering this component. 1. Shut down your system by following the steps in “Shutting Down the ISQ 7000 System” page 149. Note You do not have to remove the ion source cartridge or column. However, you must vent the instrument.
  • Page 278 9. Reattach the back manifold plate to the instrument. The back manifold plate must be reinstalled with the pin at the bottom. ISQ 7000 Hardware Manual Thermo Scientific...
  • Page 279 11. Reattach the two screws holding the power supply to the instrument. 12. Reconnect the power cables to the back of the ISQ 7000 instrument. 13. Reattach the top cover panel and tighten the screw. 14. Restart your system by following the instructions in “Restarting the System”...

  • Page 280: Source Retainer Magnets, Magnet Yoke, Source Insertion Guide, Source Magnets And Front Manifold O-Ring

    Note For information about ordering these components, see the ISQ and TSQ GC-MS Spare Parts Guide. 1. Shut down your system by following the steps in “Shutting Down the ISQ 7000 System” page 149. Note You do not have to remove the ion source cartridge or the column. However, you must vent the instrument.
  • Page 281 Guide Magnet Yoke 4. Close the manifold door and reattach the four screws. Figure 265. Closing the Manifold Door Screws 5. Restart your system by following the instructions in “Restarting the System” page 165. Thermo Scientific ISQ 7000 Hardware Manual...

  • Page 282: Vent Valve Knob And O-Ring

    Wait five minutes for venting to complete. Note If you have an ISQ 7000 without a VPI, the vent valve knob is located as seen in Figure 266.

  • Page 283: Delivery Tubes

    149. 2. Remove the analyzer tray from the instrument by following the instructions in “Removing the Analyzer Tray from the ISQ 7000 Instrument” page 151. Note You do not have to remove the ion source cartridge or the column. If you are using hydrogen as a carrier gas, power off the GC.
  • Page 284 Figure 268. Replacing the Delivery Tube Delivery Tubes 5. Replace the analyzer tray by following the instructions in “Replacing the Analyzer Tray” page 162. 6. Restart your system by following the instructions in “Restarting the System” page 165. ISQ 7000 Hardware Manual Thermo Scientific...

  • Page 285: Replacing Components Of The Electron Multiplier

    Electron Multiplier For information about replacing the electron multiplier, see Replacing the Electron Multiplier. The electron multiplier is replaced more frequently than the other components, so it is described in Chapter 1, “Performing Routine Maintenance.” Thermo Scientific ISQ 7000 Hardware Manual...

  • Page 286: Electron Multiplier Plate

    Note See the ISQ and TSQ GC-MS Spare Parts Guide for information about ordering this component. 1. Shut down your system by following the steps in “Shutting Down the ISQ 7000 System” page 149. Note You do not have to remove the ion source cartridge or the column. However, you must vent the instrument.
  • Page 287 4. Remove the two screws holding the electrometer shield to the electron multiplier plate. Figure 271. Removing the Electrometer Shield Screws 5. Remove the four screws holding the electrometer board to the electron multiplier plate. Figure 272. Removing the Electrometer Board Screws Electron Multiplier Plate Thermo Scientific ISQ 7000 Hardware Manual...
  • Page 288 Set them aside on a clean work surface. 8. Use a T20 Torxhead screwdriver to remove the four screws at each corner of the electron multiplier plate. Figure 274. Disconnecting the Electron Multiplier Plate Electron Multiplier Plate Screws ISQ 7000 Hardware Manual Thermo Scientific...
  • Page 289 Figure 275. Resting the Electron Multiplier Plate on the Worktable Electron Multiplier Plate 10. Remove the two screws connecting the electron multiplier to the plate and attach the electron multiplier to a new plate. Figure 276. Replacing the Electron Multiplier Plate Screws Thermo Scientific ISQ 7000 Hardware Manual...
  • Page 290 ATTENTION DOMMAGES À L’INSTRUMENT : ne confondez pas les câbles ou vous endommagerez l’alimentation. 19. Reattach the top cover panel and tighten the screw. 20. Restart your system by following the instructions in “Restarting the System” page 165. ISQ 7000 Hardware Manual Thermo Scientific...

  • Page 291: Large Feedthroughs

    Note See the ISQ and TSQ GC-MS Spare Parts Guide for information about ordering these components. 1. Shut down your system by following the steps in “Shutting Down the ISQ 7000 System” page 149. Note You do not have to remove the ion source cartridge or the column. However, you must vent the instrument.
  • Page 292 8. Use a T20 Torxhead screwdriver to reattach the four screws at each corner of the electron multiplier plate. 9. Reconnect the large feedthrough cables 10. Reattach the top cover panel and tighten the screw. 11. Restart your system by following the instructions in “Restarting the System” page 165. ISQ 7000 Hardware Manual Thermo Scientific...

  • Page 293: Anode Feedthrough

    Note See the ISQ and TSQ GC-MS Spare Parts Guide for information about ordering this component. 1. Shut down your system by following the steps in “Shutting Down the ISQ 7000 System” page 149. Note You do not have to remove the ion source cartridge or the column. However, you must vent the instrument.
  • Page 294 5. Lift the electrometer shield off the instrument and set it aside. 6. Use a T10 Torxhead screwdriver to remove the four screws holding the electrometer board in place. Figure 283. Removing the Electrometer Board Screws ISQ 7000 Hardware Manual Thermo Scientific...
  • Page 295 The standoff serves as the ground for the electrometer board. The center pin is the signal path for the electrons generated in the electron multiplier going into the electrometer. Thermo Scientific ISQ 7000 Hardware Manual...
  • Page 296 12. Reattach the electrometer shield and the four screws. 13. Reconnect the electrometer board cable. 14. Reattach the top cover panel and tighten the screw. 15. Restart your system by following the instructions in “Restarting the System” page 165. ISQ 7000 Hardware Manual Thermo Scientific...

  • Page 297: Upgrading The Isq 7000 System Software

    Updating the Firmware on the Instrument To update the firmware on the ISQ 7000 instrument 1. Access the ISQ Manual Tune utility by selecting Air & Water / Tune on the ISQ 7000 Dashboard. 2. Right-click Firmware in the upper right corner. A new menu opens.

  • Page 298: Upgrading Software On The Computer

    Advanced Maintenance Upgrading the ISQ 7000 System Software 5. Once the firmware is updated, open the front door of the ISQ 7000 mass spectrometer and press the Reset button on the interior front panel. This button allows the instrument to reestablish communication with the computer.

  • Page 299: System Requirements

    • Thermo Scientific™ TraceFinder™ software • Thermo Scientific™ Dionex™ Chromeleon software Check release notes for compatibility with ISQ 7000 instrument control software. Check release notes for compatibility with Thermo Foundation, Xcalibur, and ISQ 7000 instrument control software. Thermo Scientific ISQ 7000 Hardware Manual...

  • Page 300: Installing The Software Set

    Advanced Maintenance Upgrading the ISQ 7000 System Software Installing the Software Set To install the system software set: Note Check the latest Xcalibur Core Components for GC-MS CD for the most recent version of these installation instructions. To view the installation help document, select Browse CD and open the TSQ 9000 Installation Help pdf.
  • Page 301 Advanced Maintenance Upgrading the ISQ 7000 System Software 6. Click on the NIST Browser button to install the NIST MS Browser. This functionality is required to allow automatic searching of libraries from Xcalibur or layered applications. Install the NIST Browser according to the installation instructions. The NIST installer will automatically create the required folders for the browser and demo libraries.
  • Page 302 Advanced Maintenance Upgrading the ISQ 7000 System Software 3. After the software has located the configuration of the LAN CPU, right-click on the IP address for the LAN CPU and select Configure. 4. Click the Operating Mode tab, check the Modify checkbox, and click Settings.

  • Page 303: Replacing The Covers Of The Isq 7000 Mass Spectrometer

    Advanced Maintenance Replacing the Covers of the ISQ 7000 Mass Spectrometer Replacing the Covers of the ISQ 7000 Mass Spectrometer If the covers of your instrument get damaged, you can use the illustration below to visually locate a component and then follow the process to replace it.

  • Page 304: Top Cover Panel

    2. Use a T20 Torxhead screwdriver to loosen the top cover panel screw from the interior front panel. Then slide the top cover panel toward the back of the instrument and lift it off. Figure 290. Replacing the Top Cover Panel of the ISQ 7000 Instrument Top Cover Panel Screw Top Cover Panel 3.

  • Page 305: Left Side Panel

    Replacing the Covers of the ISQ 7000 Mass Spectrometer Left Side Panel  To replace the left side panel of the ISQ 7000 instrument Note See the ISQ and TSQ GC-MS Spare Parts Guide for information about ordering this component.

  • Page 306: Right Side Panel

    Note You do not have to remove the ion source cartridge. However, you must remove the column and vent the instrument. 2. If the ISQ 7000 mass spectrometer is too close to the GC, move them apart so you can access the right side panel.
  • Page 307 Figure 293. Replacing the Right Side Panel 5. Replace the right side panel and attach the screws holding it in place. 6. Slide the ISQ 7000 instrument closer to the GC. 7. Restart your system by following the instructions in “Restarting the System”...

  • Page 308: Top Manifold Cover

    Advanced Maintenance Replacing the Covers of the ISQ 7000 Mass Spectrometer Top Manifold Cover  To replace the top manifold cover Note See the ISQ and TSQ GC-MS Spare Parts Guide for information about ordering this component. 1. Shut down your system by following the steps in “Shutting Down the ISQ 7000 System”...

  • Page 309: Replacing The Chassis Feet

    Replacing the Covers of the ISQ 7000 Mass Spectrometer Replacing the Chassis Feet  To replace the chassis feet on the bottom of the ISQ 7000 instrument Note See the ISQ and TSQ GC-MS Spare Parts Guide for information about ordering this component.
  • Page 310 6. Attach the new chassis feet. The dimensions are in Figure 296. Figure 296. Dimensions of the Feet on the Bottom of the ISQ 7000 Instrument 3 in (8 cm) from back 4.5 in (12 cm) from foot to back of...

  • Page 311: Replacing Components Of The Front Door

    Replacing Components of the Front Door Replacing Components of the Front Door If the front door of your ISQ 7000 instrument gets damaged, you can use the illustration below to visually locate a replaceable component and then follow the process to replace it.

  • Page 312: Front Door Hinges And Supports

    Note See the ISQ and TSQ GC-MS Spare Parts Guide for information about ordering this component. 1. Shut down your system by following the steps in “Shutting Down the ISQ 7000 System” page 149. Note You do not have to remove the ion source cartridge or the column or vent the instrument.
  • Page 313 7. Use a T20 Torxhead screwdriver to remove the screw connecting each hinge support to the interior front panel. Figure 300. Replacing the Hinge Supports Hinge Support Thermo Scientific ISQ 7000 Hardware Manual...
  • Page 314 Figure 301. Reattaching the Nut and Grounding Washer Grounding Washer 10. Reattach the right side panel. 11. Close the front door of the instrument. 12. Restart your system by following the instructions in “Restarting the System” page 165. ISQ 7000 Hardware Manual Thermo Scientific...

  • Page 315: Front Door Latch

    Note See the ISQ and TSQ GC-MS Spare Parts Guide for information about ordering this component. 1. Shut down your system by following the steps in “Shutting Down the ISQ 7000 System” page 149. Note You do not have to remove the ion source cartridge or the column. However, you must vent the instrument.
  • Page 316 (location shown below) that will fall out as your remove the knob. Be sure to catch them and set them aside. Figure 303. Removing the Vacuum Interlock Knob Screws Spring and safety interlock are behind this screw Vacuum Interlock Shield ISQ 7000 Hardware Manual Thermo Scientific...
  • Page 317 Figure 304. Disconnecting the Vacuum Interlock Cable Tubing Vacuum Interlock Cable Connector 7. Pinch together the two springs on the left side the vacuum interlock shield to remove it. Figure 305. Removing the Vacuum Interlock Shield Vacuum Interlock Shield Springs Thermo Scientific ISQ 7000 Hardware Manual...
  • Page 318 9. Disconnect the electrical wires from the electrical connector. If you are using a single-level calibration gas controller, there is only one electrical connector. 10. Use a 5/16 in. wrench to remove the fitting connected to the tubing and move the tubing out of the way. ISQ 7000 Hardware Manual Thermo Scientific...
  • Page 319 17. Reattach the screws around the vacuum interlock knob. 18. Reattach the vacuum interlock knob. 19. Reattach the left side panel and tighten the screw. 20. Restart your system by following the instructions in “Restarting the System” page 165. Thermo Scientific ISQ 7000 Hardware Manual...

  • Page 320: Replacing The Boards In The Isq 7000 Mass Spectrometer

    Replacing the Boards in the ISQ 7000 Mass Spectrometer Replacing the Boards in the ISQ 7000 Mass Spectrometer If the boards in your ISQ 7000 instrument get damaged, you can use the illustration below to visually locate a board and then follow the process to replace it.

  • Page 321: Rf Board And Rod Driver Board

    Then slide the top cover panel toward the back of the instrument and lift it off. 3. The RF board is the second board standing on end toward the center of the ISQ 7000 instrument. Use a T20 Torxhead screwdriver to loosen the screw holding the board and bracket to the chassis.
  • Page 322 Advanced Maintenance Replacing the Boards in the ISQ 7000 Mass Spectrometer 7. Use a nut driver to remove the two 4.5 mm standoffs on the rod driver board. Figure 310. Disconnecting the Rod Driver Board from the RF Board Screws...
  • Page 323 Advanced Maintenance Replacing the Boards in the ISQ 7000 Mass Spectrometer 9. Pry the 7-pin connector on the rod driver board away from the RF board. Figure 312. Disconnecting the Rod Driver Board 7-Pin Connector 7-Pin Connector 10. If necessary, replace the rod driver board.
  • Page 324 Advanced Maintenance Replacing the Boards in the ISQ 7000 Mass Spectrometer 12. Insert a new RF board by aligning the connectors on the bottom of the board with the connectors on the distribution board beneath it. It will drop into the slot when it is in the right position.
  • Page 325 Advanced Maintenance Replacing the Boards in the ISQ 7000 Mass Spectrometer Note The new RF board will have a slightly different performance than your current board. It will need to be adjusted by a Field Service Engineer because the adjustments must be made while the system is running.

  • Page 326: Rf Board/Rod Driver Board Kit

    Then slide the top cover panel toward the back of the instrument and lift it off. 3. The RF board is the second board standing on end toward the center of the ISQ 7000 instrument. Use a T20 Torxhead screwdriver to loosen the screw holding the board and bracket to the chassis.
  • Page 327 Advanced Maintenance Replacing the Boards in the ISQ 7000 Mass Spectrometer 5. Lift the RF board out of the mass spectrometer. The rod driver board is attached to it. Figure 317. Replacing the RF Board/Rod Driver Board Kit 6. Insert a new RF board/rod driver board kit by aligning the connectors on the bottom of the board with the connectors on the distribution board beneath it.
  • Page 328 Advanced Maintenance Replacing the Boards in the ISQ 7000 Mass Spectrometer 7. Push the board down into the connectors. 8. Gently push the board toward the instrument, carefully aligning the board over the feedthrough pins, until it stops. 9. Reattach the screw holding the RF board to the bracket.

  • Page 329: 4- Pin Feedthrough

    Advanced Maintenance Replacing the Boards in the ISQ 7000 Mass Spectrometer 4- Pin Feedthrough  To replace the 4-pin feedthrough: Note See the ISQ and TSQ GC-MS Spare Parts Guide for information about ordering these components. 1. Shut down your system by following the steps in “Shutting Down the ISQ 7000 System”...
  • Page 330 Advanced Maintenance Replacing the Boards in the ISQ 7000 Mass Spectrometer 4. Use a T20 Torxhead screwdriver to remove the four screws at each corner of the electron multiplier plate. Figure 321. Disconnecting the Electron Multiplier Plate Electron Multiplier Plate Screws 5.
  • Page 331 Replacing the Boards in the ISQ 7000 Mass Spectrometer 7. The RF board is the second board standing on end toward the center of the ISQ 7000 instrument. Use a T20 Torxhead screwdriver to loosen the screw holding the board to the top of the chassis.
  • Page 332 Advanced Maintenance Replacing the Boards in the ISQ 7000 Mass Spectrometer 11. Remove and replace the 4-pin feedthrough. You can also remove the o-ring and screws, if necessary. 12. Reattach the replacement 4-pin feedthrough to the chassis. 13. Reinsert the RF board by aligning the connectors on the bottom of the board with the connectors on the distribution board beneath it.
  • Page 333 Advanced Maintenance Replacing the Boards in the ISQ 7000 Mass Spectrometer 16. Reattach the screw holding the RF board in place. Figure 326. Reattaching the RF Board and Bracket RF Board Chassis Screw Bracket Note This screw is required for good ground contact.
  • Page 334 Advanced Maintenance Replacing the Boards in the ISQ 7000 Mass Spectrometer 18. Use a Torxhead screwdriver to reattach the four screws at each corner of the electron multiplier plate. Figure 328. Reattaching the Electron Multiplier Plate Electron Multiplier Plate Screws 19.

  • Page 335: Lens Driver Board

    Advanced Maintenance Replacing the Boards in the ISQ 7000 Mass Spectrometer Lens Driver Board  To replace the lens driver board Note See the ISQ and TSQ GC-MS Spare Parts Guide for information about ordering this component. 1. Shut down your system by following the steps in “Shutting Down the ISQ 7000 System”...
  • Page 336 Advanced Maintenance Replacing the Boards in the ISQ 7000 Mass Spectrometer 4. Look through the left side of the instrument and use a T20 Torxhead screwdriver to loosen the screw holding the board to the chassis. Loosening the screw will separate the board from the instrument.
  • Page 337 Advanced Maintenance Replacing the Boards in the ISQ 7000 Mass Spectrometer 6. Insert a new lens driver board by aligning the connector on the bottom of the board with the connectors on the distribution board beneath it. It will drop into the slot when it is in the right position.

  • Page 338: 20-Pin Feedthrough

    Advanced Maintenance Replacing the Boards in the ISQ 7000 Mass Spectrometer 20-Pin Feedthrough  To replace the 20-pin feedthrough: Note See the ISQ and TSQ GC-MS Spare Parts Guide for information about ordering this component. 1. Shut down your system by following the steps in “Shutting Down the ISQ 7000 System”...
  • Page 339 Advanced Maintenance Replacing the Boards in the ISQ 7000 Mass Spectrometer 4. Look through the left side of the instrument and use a T20 Torxhead screwdriver to loosen the screw holding the board to the chassis. Loosening the screw will separate the board from the instrument.
  • Page 340 Advanced Maintenance Replacing the Boards in the ISQ 7000 Mass Spectrometer 8. Use a T20 Torxhead screwdriver to remove the four screws around the manifold door. Figure 336. Opening the Manifold Door Screws 9. Detach the filament board from the source interface board.
  • Page 341 Advanced Maintenance Replacing the Boards in the ISQ 7000 Mass Spectrometer 11. Look through the top of the instrument and use the heat shield to pry the source interface board off of the 20-pin feedthrough. Figure 338. Detaching the Source Interface Board From the 20-Pin Feedthrough...
  • Page 342 Advanced Maintenance Replacing the Boards in the ISQ 7000 Mass Spectrometer 13. Remove and replace the 20-pin feedthrough. If necessary, replace the o-ring and make sure it is properly aligned and free of dust. Figure 340. Replacing the 20-Pin Feedthrough O-ring 14.
  • Page 343 Advanced Maintenance Replacing the Boards in the ISQ 7000 Mass Spectrometer 15. Look through the top of the instrument and align the pins on the 20-pin feedthrough with the holes in the source interface board to connect them together. Figure 342. Reattaching the Source Interface Board to the 20-Pin Feedthrough...
  • Page 344 Advanced Maintenance Replacing the Boards in the ISQ 7000 Mass Spectrometer 18. Close the manifold door and reattach the four screws. Figure 344. Closing the Manifold Door Screws 19. Reinsert the lens driver board by aligning the connector on the bottom of the board with the connectors on the distribution board beneath it.
  • Page 345 Advanced Maintenance Replacing the Boards in the ISQ 7000 Mass Spectrometer 21. Look through the left side of the instrument and tighten the screw that holds the lens driver board in place on the chassis. Figure 346. Reattaching the Lens Driver Board Lens Driver Board Screw 22.

  • Page 346: Pc Communication Board, Controller Interface Board, And Support

    Advanced Maintenance Replacing the Boards in the ISQ 7000 Mass Spectrometer PC Communication Board, Controller Interface Board, and Support Bracket  To replace the PC communication board, controller interface board, and support bracket Note See the ISQ and TSQ GC-MS Spare Parts Guide for information about ordering this component.
  • Page 347 Advanced Maintenance Replacing the Boards in the ISQ 7000 Mass Spectrometer Figure 347. Removing the Controller Interface Board Support Bracket Support Bracket Controller Interface Board Thermo Scientific ISQ 7000 Hardware Manual...
  • Page 348 Advanced Maintenance Replacing the Boards in the ISQ 7000 Mass Spectrometer 5. Locate the PC communication board, which is attached to the controller interface board. Note Although the PC communication board is attached to the controller interface board, they are sold separately. See the ISQ and TSQ GC-MS Spare Parts Guide for ordering information.
  • Page 349 Advanced Maintenance Replacing the Boards in the ISQ 7000 Mass Spectrometer 8. Incrementally, and very carefully, disconnect the PC communication board from the controller interface board by separating the two connectors. Inspect the pins to be certain they are not bent.
  • Page 350 Advanced Maintenance Replacing the Boards in the ISQ 7000 Mass Spectrometer 12. Install the controller interface board by aligning the two connectors on the bottom of the board to the connectors on the distribution board beneath it. It will drop into the slot when it is in the right position.

  • Page 351: Distribution Board

    Advanced Maintenance Replacing the Boards in the ISQ 7000 Mass Spectrometer Distribution Board The distribution board lies on the bottom of the ISQ 7000 instrument’s chassis.  To replace the distribution board Note See the ISQ and TSQ GC-MS Spare Parts Guide for information about ordering this component.
  • Page 352 Replacing the Boards in the ISQ 7000 Mass Spectrometer 4. The RF board is the second board standing on end toward the center of the ISQ 7000 instrument. Use a T20 Torxhead screwdriver to remove the screw holding the board to the top of the chassis.
  • Page 353 Advanced Maintenance Replacing the Boards in the ISQ 7000 Mass Spectrometer 7. Look through the left side of the instrument and use a T20 Torxhead screwdriver to loosen the screw holding the board to the chassis. Loosening the screw will separate the board from the instrument.
  • Page 354 Advanced Maintenance Replacing the Boards in the ISQ 7000 Mass Spectrometer 10. Remove the controller interface board. Figure 355. Removing the Controller Interface Board Controller Interface Board 11. Remove the screws that connect the dynode/multiplier power supply to the back and bottom of the chassis.
  • Page 355 Advanced Maintenance Replacing the Boards in the ISQ 7000 Mass Spectrometer 12. Disconnect the large feedthrough cables on the electron multiplier plate. Figure 357. Disconnecting the Large Feedthrough Cables Large Electron Multiplier Plate 13. Remove the power supply system by removing the two screws on the back of the instrument.
  • Page 356 Advanced Maintenance Replacing the Boards in the ISQ 7000 Mass Spectrometer 14. Lift up on the bracket of the power supply. 15. Now that all of the components have been removed from the distribution board, you can see that it lies flat on the bottom of the chassis.
  • Page 357 Advanced Maintenance Replacing the Boards in the ISQ 7000 Mass Spectrometer 21. Slide the main power supply back down into its slot. Once it is in the slot, squeeze the sides of the instrument together slightly while you are reattaching the screws on the back of the instrument.Otherwise the top cover panel will not fit perfectly.
  • Page 358 Advanced Maintenance Replacing the Boards in the ISQ 7000 Mass Spectrometer 23. Reconnect the large feedthrough cables on the electron multiplier plate. Figure 362. Reconnecting the Large Feedthrough Cables Electrometer Board Cable Large Electron Multiplier Plate 24. Reattach the RF board by aligning the connectors on the bottom of the board with the connectors on the distribution board beneath it.
  • Page 359 Advanced Maintenance Replacing the Boards in the ISQ 7000 Mass Spectrometer 27. Reattach the screw holding the RF board to the bracket. Figure 364. Reattaching the RF Board and Bracket RF Board Chassis Screw Bracket Note This screw is required for good ground contact.
  • Page 360 Advanced Maintenance Replacing the Boards in the ISQ 7000 Mass Spectrometer 29. Push the board down into the connector. 30. Look through the left side of the instrument and use a T20 Torxhead screwdriver to tighten the screw holding the lens driver board in place on the chassis.
  • Page 361 Advanced Maintenance Replacing the Boards in the ISQ 7000 Mass Spectrometer 32. Reconnect the Ethernet cable to the chassis and the PC communication board. 33. Reattach the support bracket on the left side of the instrument. Figure 368. Reattaching the Support Bracket Support Bracket 34.

  • Page 362: Source Interface Board And Heat Shield

    Advanced Maintenance Replacing the Boards in the ISQ 7000 Mass Spectrometer Source Interface Board and Heat Shield  To replace the source interface board and heat shield Note See the ISQ and TSQ GC-MS Spare Parts Guide for information about ordering these components.
  • Page 363 Advanced Maintenance Replacing the Boards in the ISQ 7000 Mass Spectrometer 6. Set the analyzer tray on a clean, lint-free surface. 7. Hold the new source interface board next to the old board. 8. As you remove each of the wires from the old board, connect them to the same connectors on the new board.

  • Page 364: Electrometer Board Cable

    Advanced Maintenance Replacing the Boards in the ISQ 7000 Mass Spectrometer Electrometer Board Cable  To replace the electrometer board (15-pin male/female RS-232) cable Note See the ISQ and TSQ GC-MS Spare Parts Guide for information about ordering this component.
  • Page 365 Large Electron Multiplier Plate 5. The RF board is the second board standing on end toward the center of the ISQ 7000 instrument. Use a T20 Torxhead screwdriver to remove the screw holding the board and bracket to the chassis.
  • Page 366 Advanced Maintenance Replacing the Boards in the ISQ 7000 Mass Spectrometer 6. Use your fingers to pry the bracket of the board away from the chassis and toward the left side of the instrument. 7. Lift the board out of the instrument.
  • Page 367 Advanced Maintenance Replacing the Boards in the ISQ 7000 Mass Spectrometer 10. Use a T20 Torxhead screwdriver to remove the screws connecting the dynode/multiplier power supply to the back and bottom of the chassis. Figure 375. Removing the Dynode/Multiplier Power Supply...
  • Page 368 Advanced Maintenance Replacing the Boards in the ISQ 7000 Mass Spectrometer 15. Push the board down into the connectors. 16. Reconnect the Ethernet cable to the PC communication board. 17. Reinstall the RF board by aligning the connectors on the bottom of the board with the connectors on the distribution board beneath it.
  • Page 369 Advanced Maintenance Replacing the Boards in the ISQ 7000 Mass Spectrometer 20. Reinstall the dynode/multiplier power supply by aligning its connector with the connector on the distribution board beneath it. It will drop into the slot when it is in the right position.
  • Page 370 Advanced Maintenance Replacing the Boards in the ISQ 7000 Mass Spectrometer 23. Reconnect the large feedthrough cables. Figure 381. Reconnecting the Large Feedthrough Cables Large Electron Multiplier Plate 24. Reattach the support bracket on the left side of the instrument.

  • Page 371: Electrometer Board And Shield

    Advanced Maintenance Replacing the Boards in the ISQ 7000 Mass Spectrometer Electrometer Board and Shield  To replace the electrometer board and shield Note See the ISQ and TSQ GC-MS Spare Parts Guide for information about ordering these components. 1. Shut down your system by following the steps in “Shutting Down the ISQ 7000 System”...
  • Page 372 Advanced Maintenance Replacing the Boards in the ISQ 7000 Mass Spectrometer 4. Use a T10 Torxhead screwdriver to remove the two screws holding the electrometer shield in place. Figure 384. Removing the Electrometer Shield Screws 5. Lift the back of the electrometer shield and slide it toward the front of the instrument to remove it.
  • Page 373 Advanced Maintenance Replacing the Boards in the ISQ 7000 Mass Spectrometer 7. Remove and replace the electrometer board. 8. Reattach the screws that hold the electrometer board in place. 9. Reattach the electrometer shield and screws. Tip To prevent the screws from falling down into the instrument, place them on the shield before you reattach it to the chassis.

  • Page 374: Replacing The Power Supplies

    Replacing the Power Supplies Replacing the Power Supplies If the power supplies in your ISQ 7000 instrument get damaged, you can use the illustration below to visually locate a power supply and then follow the process to replace it. Figure 387. Replaceable Power Supplies in the ISQ 7000 Instrument...

  • Page 375: Power Supply System

    Note See the ISQ and TSQ GC-MS Spare Parts Guide for information about ordering this component. 1. Shut down your system by following the steps in “Shutting Down the ISQ 7000 System” page 149. Note You do not have to remove the ion source cartridge or the column or vent the instrument.
  • Page 376 The foreline pump connects to the System Mech Pump connector on the back of the instrument. 10. Reattach the top cover panel and tighten the screw holding it in place. 11. Restart your system by following the instructions in “Restarting the System” page 165. ISQ 7000 Hardware Manual Thermo Scientific...

  • Page 377: Dynode And Multiplier Power Supply

    Note See the ISQ and TSQ GC-MS Spare Parts Guide for information about ordering this component. 1. Shut down your system by following the steps in “Shutting Down the ISQ 7000 System” page 149. Note You do not have to remove the ion source cartridge or the column or vent the instrument.
  • Page 378 5. Use a T20 Torxhead screwdriver to remove the screws connecting the dynode/multiplier power supply to the back and bottom of the chassis. Figure 391. Removing the Dynode/Multiplier Power Supply Back Screws Dynode/Multiplier Power Supply Bottom Screw ISQ 7000 Hardware Manual Thermo Scientific...
  • Page 379 8. Push the power supply down into the connector. 9. Reattach the screws holding the dynode and multiplier power supply in place. Figure 393. Reinstalling the Dynode/Multiplier Power Supply Back Screws Dynode/Multiplier Power Supply Bottom Screw Thermo Scientific ISQ 7000 Hardware Manual...
  • Page 380 Figure 395. Reattaching the Controller Interface Board Support Bracket Support Bracket 12. Reattach the top cover and left side panels and tighten the screws. 13. Restart your system by following the instructions in “Restarting the System” page 165. ISQ 7000 Hardware Manual Thermo Scientific...

  • Page 381: Replacing The Calibration Gas Components

    Figure 396. Replaceable Calibration Gas Components Source Gas Gas Mixing Tubes Chamber Calibration Gas Module Transfer Line Calibration Gas Line Calibrant Reservoir Kit Thermo Scientific ISQ 7000 Hardware Manual...

  • Page 382: Calibration Gas Module

    Note See the ISQ and TSQ GC-MS Spare Parts Guide for information about ordering this component. 1. Shut down your system by following the steps in “Shutting Down the ISQ 7000 System” page 149. Note You do not have to remove the ion source cartridge or the column. However, you must vent the instrument.
  • Page 383 6. Look through the top of the instrument and locate the RF board. It is the second board standing on end toward the center of the ISQ 7000 instrument. Use a T20 Torxhead screwdriver to loosen the screw holding the board and bracket to the chassis.
  • Page 384 Tip The bracket has a white diagram describing the location of this screw. It is approximately one inch from the top of the board directly under the white label. Figure 401. Removing the Lens Driver Board Lens Driver Board Screw ISQ 7000 Hardware Manual Thermo Scientific...
  • Page 385 12. Remove the controller interface board from the instrument. 13. Reach through the left side of the instrument and disconnect the vacuum line tubing that goes from the foreline connector to the calibration gas module. Thermo Scientific ISQ 7000 Hardware Manual...
  • Page 386 Note If you are using CI, you will have P1 and P2 electrical wires. 15. Disconnect the P1 and P2 electrical wires from the front of the calibration gas module. Note If you have a single-level calibration gas module, your ISQ 7000 instrument only has a P1 connector.
  • Page 387 22. Gently push the board toward the instrument, carefully aligning the board over the feedthrough pins, until it stops. 23. Reattach the screw holding the RF board to the bracket. Figure 405. Reattaching the RF Board and Bracket RF Board Chassis Screw Bracket Thermo Scientific ISQ 7000 Hardware Manual...
  • Page 388 26. Look through the left side of the instrument and use a T20 Torxhead screwdriver to reattach the screw holding the lens driver board in place on the chassis. Figure 407. Reattaching the Lens Driver Board Lens Driver Board Screw ISQ 7000 Hardware Manual Thermo Scientific...
  • Page 389 It will drop into the slots when it is in the right position. Figure 408. Reinstalling the Control Interface Board Connectors 29. Reattach the support bracket. Figure 409. Reattaching the Controller Interface Board Support Bracket Support Bracket Thermo Scientific ISQ 7000 Hardware Manual...
  • Page 390 Figure 410. Closing the Manifold Door Screws 32. Reattach the top cover and left side panels and tighten the screws. 33. Restart your system by following the instructions in “Restarting the System” page 165. ISQ 7000 Hardware Manual Thermo Scientific...

  • Page 391: Calibrant Reservoir Kit

    Figure 412. Replacing the Calibrant Reservoir and Cover Calibrant Reservoir Calibrant Reservoir Cover 5. Close the front door panel of the instrument. 6. If you are using hydrogen as a carrier gas, replace the front door panel screw. Thermo Scientific ISQ 7000 Hardware Manual...

  • Page 392: Gas Mixing Chamber

    149. 2. Remove the analyzer tray from the instrument by following the instructions in “Removing the Analyzer Tray from the ISQ 7000 Instrument” page 151. 3. Use a T20 Torxhead screwdriver to remove the two screws holding the gas mixing chamber to the ion source block.

  • Page 393: Transfer Line

    Note See the ISQ and TSQ GC-MS Spare Parts Guide for information about ordering these components. 1. Shut down your system by following the steps in “Shutting Down the ISQ 7000 System” page 149. 2. Use a T20 Torxhead screwdriver to loosen the top cover panel screw from the interior front panel.
  • Page 394 Note If you are using CI gas, there are two tubes connected. If you are using an EI system, there is one tube and one blanking ferrule connected. Figure 416. Disconnecting the Transfer Line Tubing Connectors ISQ 7000 Hardware Manual Thermo Scientific...
  • Page 395 14. Reattach the screws and standoffs holding the transfer line to the chassis. 15. Reconnect the electrical cable to the connector. Figure 418. Reconnecting the Transfer Line Electrical Cable and Screws Electrical Cable Screws Thermo Scientific ISQ 7000 Hardware Manual...
  • Page 396 18. Slide the right side panel back onto the instrument and reattach the screws. 19. Replace the top cover and tighten the screws. 20. Reposition the instrument closer to the GC. 21. Restart your system by following the instructions in “Restarting the System” page 165. ISQ 7000 Hardware Manual Thermo Scientific...

  • Page 397: Replacing Fans And Filters

    Replacing Fans and Filters Replacing Fans and Filters To efficiently cool the ISQ 7000 instrument while it is being used, air must be allowed to flow in through the front of the instrument and out the back. The instrument is equipped with a fan that keeps the air flowing and optional filters that minimize the amount of dust that enters the system.

  • Page 398: Intake Filters And Rf Shields

    3. Use a T10 Torxhead screwdriver to remove the two screws holding the intake filters and RF shields to the interior front panel. 4. Remove and replace the intake filters and RF shields. Figure 421. Replacing the Filters on the ISQ 7000 Instrument Intake Filter/RF...

  • Page 399: Chassis Cooling Fan

    Note See the ISQ and TSQ GC-MS Spare Parts Guide for information about ordering this component. 1. Shut down your system by following the steps in “Shutting Down the ISQ 7000 System” page 149. Note You do not have to remove the ion source cartridge or the column or vent the instrument.
  • Page 400 Advanced Maintenance Replacing Fans and Filters ISQ 7000 Hardware Manual Thermo Scientific...

  • Page 401: Chapter 4 Upgrade Equipment

    Upgrade Equipment This chapter describes how to install the upgrade equipment that is available for the ISQ 7000 mass spectrometer. See the ISQ and TSQ GC-MS Spare Parts Guide for information about ordering the equipment in this chapter. Contents •...

  • Page 402: Advanced Ei Ion Source

    Advanced EI Ion Source Advanced EI Ion Source If you did not order a ISQ 7000 system with an Advanced EI ion source, you can order a system later. You must change the source magnets on the manifold door to use an Advanced EI source.
  • Page 403 Figure 425. Assembling the Advanced EI Source Magnets and Yoke Advanced EI Magnet Yoke Source Magnets 8. Attach the source magnets and yoke to the manifold door using the new tray alignment pins in the Advanced EI source kit. See Figure 426. Thermo Scientific ISQ 7000 Hardware Manual...
  • Page 404 Figure 426. Attaching the Magnets and Yoke to the Manifold Door 9. Use a T20 Torx key to align the magnets correctly. See Figure 427. Figure 427. Aligning the Magnets 10. Use the same T20 Torx key to tighten the magnets. See Figure 428. ISQ 7000 Hardware Manual Thermo Scientific...
  • Page 405 Figure 429. Removing the ExtractaBrite Ion Source 12. Remove the AEI Source from the case. See Figure 430. Figure 430. Removing the AEI Source from the Storage 13. Install the AEI Source manually. See Figure 431. Thermo Scientific ISQ 7000 Hardware Manual...
  • Page 406 Figure 432. Attaching the Wires to the Source Interface Board 15. Reattach the manifold door and the four screws. 16. Restart your system by following the instructions in “Powering On the ISQ 7000 Mass Spectrometer” page 17. Store the ExtractaBrite source and the magnet parts in the AEI Case and screw the case insert top down.
  • Page 407 Upgrade Equipment Advanced EI Ion Source Figure 433. Storing Extra Source Parts in the AEI Source Case Thermo Scientific ISQ 7000 Hardware Manual...

  • Page 408: Dust Filters

    Dust Filters Dust Filters There are two dust filters available for the ISQ 7000 mass spectrometer. They provide an extra layer of filtration for the air that cools the system. If you have a particularly dusty environment, these filters will help your instrument operate at a cooler temperature for a longer period of time.

  • Page 409: Ci Reagent Gas Flow Module

    Then slide the left and top cover panels toward the back of the instrument and lift them off. 3. If the ISQ 7000 mass spectrometer is too close to the GC, move them apart so you can access the right side panel.
  • Page 410 8. On the exterior side of the back panel, use a T20 Torxhead screwdriver to attach the two screws holding the CI reagent gas flow module to the instrument. Figure 437. Attaching the CI Gas Flow Module to the Instrument Screws ISQ 7000 Hardware Manual Thermo Scientific...
  • Page 411 9. Attach the stainless steel tubes to the transfer line. Figure 438. Attaching the Tubing to the Transfer Line Transfer Line Tubing Connector 10. Remove the top manifold cover. Figure 439. Removing the Top Manifold Cover Top Manifold Cover Thermo Scientific ISQ 7000 Hardware Manual...
  • Page 412 Figure 440. Attaching the Tubing to the Mixing Chamber and Manifold Wall Tubing Gas Mixing Chamber Manifold Wall 12. Reattach the top manifold cover. ISQ 7000 Hardware Manual Thermo Scientific...
  • Page 413 Figure 441. Removing the Dynode/Multiplier Power Supply Back Screws Bottom Screws 14. Attach the CI reagent gas controller cable to the distribution board. Figure 442. Attaching the CI Reagent Gas Cable to Distribution Board CI Reagent Gas Flow Module Connector Thermo Scientific ISQ 7000 Hardware Manual...
  • Page 414 Make sure these gases are properly exhausted and all gas fittings on the system are leak-free. Consult your local Environmental and Safety Regulations for information about how to properly exhaust fumes from your laboratory. ISQ 7000 Hardware Manual Thermo Scientific...
  • Page 415 19. Slide the right side panel back onto the instrument and reattach the screws. 20. Reattach the top cover panel and left side panel and tighten the screws. 21. Restart your system by following the instructions in “Restarting the System” page 123. Thermo Scientific ISQ 7000 Hardware Manual...

  • Page 416: Ci Ion Volume

    Insulator Locking Ring Repeller Spring Ion Cartridge Sleeve Lens 1 Lens 3/RF Lens Repeller Repeller Figure 445. Ion Volumes Available for the ISQ Mass Spectrometer EI Ion Volume CI Ion Volume EI/CI Ion Volume ISQ 7000 Hardware Manual Thermo Scientific...

  • Page 417: Ei/Ci Ion Volume

    Insulator Repeller Spring Ion Cartridge Sleeve Lens 1 Lens 3/RF Lens Repeller Repeller Nut Figure 447. Ion Volumes Available for the ISQ 7000 Mass Spectrometer CI Ion Volume EI Ion Volume EI/CI Ion Volume Thermo Scientific ISQ 7000 Hardware Manual...

  • Page 418: Ion Gauge

    4. Attach the ion gauge shield and tube to the board, as shown in the figure below. Note The metal tube can be placed on the board in two different ways. Only one of the orientations will allow the tube to attache correctly to the manifold. ISQ 7000 Hardware Manual Thermo Scientific...
  • Page 419 This will prevent the o-ring from sliding off when the assembly is being put on the manifold. 7. Remove the plug on the bottom of the manifold. Figure 450. Connecting the Ion Gauge Cable to the Distribution Board Manifold Plug Thermo Scientific ISQ 7000 Hardware Manual...
  • Page 420 Figure 451. Attaching the O-Ring to the Ion Gauge Tube Tube O-Ring 9. Use a T20 Torxhead screwdriver to carefully attach the three screws holding the ion gauge tube shield to the manifold. Figure 452. Installing the Ion Gauge ISQ 7000 Hardware Manual Thermo Scientific...
  • Page 421 12. Slide the instrument closer to the GC. 13. Reattach the top cover panel and tighten the screw holding the top cover panel in place. 14. Restart your system by following the instructions in “Restarting the System” page 123. Thermo Scientific ISQ 7000 Hardware Manual...

  • Page 422: Convectron Gauge And Foreline Adapter With Hose

    Figure 454. Removing the Right Side Panel Right Side Panel Screws 3. Disconnect the vacuum hose from the adapter on the foreline pump. 4. Remove the rough pump clamp on the turbo pump and the adapter. ISQ 7000 Hardware Manual Thermo Scientific...
  • Page 423 9. Reattach the right side panel and the screws holding it in place. 10. Slide the instrument closer to the GC. 11. Restart your system by following the instructions in “Restarting the System” page 123. Thermo Scientific ISQ 7000 Hardware Manual...

  • Page 424: Turbomolecular Pumps

    3. Use a T20 Torxhead screwdriver to remove the screw at each outside corner of the right side panel. Figure 456. Removing the Right Side Panel Right Side Panel Screws 4. Make sure the electrometer board cable is not in the way when you remove the power supply system. ISQ 7000 Hardware Manual Thermo Scientific...
  • Page 425 8. Disconnect the turbo pump cable from the distribution board. Figure 458. Disconnecting the Turbo Pump Cable From the Distribution Board Turbo Pump Cable Connector 9. Remove the clamp that connects the foreline adapter to the turbo pump. Thermo Scientific ISQ 7000 Hardware Manual...
  • Page 426 13. Lift the turbo pump away from the remaining clamps. 14. Remove the turbo pump from the chassis. You may have to tilt the turbo pump to get it out of the chassis. ISQ 7000 Hardware Manual Thermo Scientific...
  • Page 427 19. Attach the adapter to the turbo pump and clamp it in place. 20. Connect the turbo pump cable to the 15-pin connector on the distribution board. Figure 460. Reconnecting the Turbo Pump Cable to the Distribution Board Turbo Pump Cable Connector Thermo Scientific ISQ 7000 Hardware Manual...
  • Page 428 24. Slide the instrument closer to the GC. 25. Reattach the top cover panel and tighten the screw holding the top cover panel in place. 26. Restart your system by following the instructions in “Restarting the System” page 123. ISQ 7000 Hardware Manual Thermo Scientific...

  • Page 429: Installing An Extended Capacity Turbomolecular Pump

    3. Use a T20 Torxhead screwdriver to remove the screw at each outside corner of the right side panel. Figure 461. Removing the Right Side Panel Right Side Panel Screws 4. Make sure the electrometer board cable is not in the way when you remove the power supply system. Thermo Scientific ISQ 7000 Hardware Manual...
  • Page 430 8. Disconnect the turbo pump cable from the distribution board. Figure 463. Disconnecting the Turbo Pump Cable from the Distribution Board Turbo Pump Cable Connector 9. Remove the clamp that connects the foreline adapter to the turbo pump. ISQ 7000 Hardware Manual Thermo Scientific...
  • Page 431 13. Lift the turbo pump away from the remaining clamps. 14. Remove the turbo pump from the chassis. You may have to tilt the turbo pump to get it out of the chassis. Thermo Scientific ISQ 7000 Hardware Manual...
  • Page 432 21. Connect the power cables on the back of the instrument. Make sure you attach the cables properly. The foreline pump connects to the System Mech Pump connector on the back of the instrument. ISQ 7000 Hardware Manual Thermo Scientific...
  • Page 433 24. Slide the instrument closer to the GC. 25. Reattach the top cover panel and tighten the screw holding it in place. 26. Restart your system by following the instructions in “Restarting the System” page 123. Thermo Scientific ISQ 7000 Hardware Manual...

  • Page 434: Probe Controllers

     To install a DIP or DEP 1. Place the direct probe controller on top of or near the ISQ 7000 instrument. 2. Connect the 9-pin cable to the direct probe controller and to the Accessory Start connector on the left hand sub panel of the instrument.
  • Page 435 (standalone) calibrant, refilling, illustration, calibration gas components anode feedthrough replacing illustration, replacing, calibrant reservoir kit, axle bearing, replacing, calibration gas controller, axle seal, replacing, transfer line, calibration gas controller Thermo Scientific ISQ 7000 Hardware Manual...
  • Page 436 4-pin feedthrough, vent valve knob and o-ring, controller interface board, power supplies distribution board, electrometer board and shield, dynode and multiplier power supply, electrometer board cable, power supply system, ISQ 7000 Hardware Manual Thermo Scientific...
  • Page 437 Temperature Check, feedthroughs Vacuum System Check, 20-pin, Direct Exposure Probe (DEP), 4-pin, Direct Insert Probe (DIP) controller, anode, large, distribution board illustration, feet, bottom of instrument, replacing, replacing, filament documentation survey increasing life of, xxviii Thermo Scientific ISQ 7000 Hardware Manual...
  • Page 438 (CI), powering off, ion volume (EI/CI), advanced troubleshooting, heat shield, replacing, configuring, ISQ 7000 Hardware Manual Thermo Scientific...
  • Page 439 Heaters, power supply system, Power, Power Supply Check diagnostics, about, Vacuum, power supply issues, investigating, powering off the ISQ, powering on the ISQ, maintenance probe controllers cleaning the filters, installing, Thermo Scientific ISQ 7000 Hardware Manual...
  • Page 440 223, 243, covers valve axle, RF board chassis feet, illustration, 293, 298, left side panel, replacing, right side panel, RF board/rod driver board kit ISQ 7000 Hardware Manual Thermo Scientific...
  • Page 441 194, 196, 198, replacing, standard capacity, troubleshooting, spring in vacuum interlock, replacing, 223, 243, stability issues, investigating, standard capacity turbomolecular pump illustration, upgrade equipment Thermo Scientific ISQ 7000 Hardware Manual...
  • Page 442 Vacuum System Check diagnostics, about, vacuum, achieving, valve axle, replacing, vent valve knob and o-ring, replacing, V-lock source plug WEEE compliance ISQ 7000 Hardware Manual Thermo Scientific...

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