RADIOMETER ABL800 FLEX Operator's Manual page 23

ABL800 FLEX Operator's Manual
Limitations of use and known interfering substances,
Continued
Anticoagulants (sampling)
CAUTION -
Known
interfering
substances
(continued)
Thiocyanic acid (degradation
product from treatment with
nitroprussid. Also produced in
thiosulphate treatment of cyanide
poisoning)
Glycolic acid (ethyleneglycol
degradation product)
Insufficiently stabilized blood.
Caustic fluids (e.g. strong acids
or bases, detergents, etc.).
Fluids that precipitate.
Fluids that affect the sensor
enzymes.
Fluids that form complexes with
the analyzer solutions (calcium).
High viscosity fluids.
Hydrophobic fluids.
Reactive fluids.
Substance Interference
Anticoagulants that contain sodium salts will
give erroneously high c Na
fluoride with or without EDTA and oxalate
(di Na) influence c Glu results. Sodium fluoride
gives erroneously high c Na
c Glu and c Lac results. Tri sodium citrate
+ +
influences c Na , c K and c Glu results.
Thus Radiometer recommends the exclusive use
of heparin as anticoagulant. Solutions containing
organic preservatives may damage the ion-
selective membranes of the c K
electrodes when introduced into the analyzer.
Do not use EDTA, as it leads to erroneous pH,
+ +
p CO , c Na , c K and c Ca
2
EDTA will also affect subsequent measurements
on the Ca electrode and it will reduce the
lifetime of this electrode.
Erroneously high c Glu and c Lac measurements.
Erroneously high c Lac measurements.
Other fluids mode allows you to measure on
fluids other than heparinized human blood.
Be aware that some substances, such as listed in
the left column, measured in the Other fluids
mode may damage the instrument or the
electrodes. This can affect the subsequent
measurement on human blood or quality control
solutions.
1. Introduction
+
results. Sodium
+ 2+
and low c Ca ,
+
and c Glu
2+
results. Use of
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