Page 1 TSQ 8000 Evo Mass Spectrometer Hardware Manual 1R120586-0003 Revision A July 2014...
Page 2 © 2014 Thermo Fisher Scientific Inc. All rights reserved. Xcalibur, TSQ 8000, TRACE 1300, TRACE 1310, and TriPlus RSH are trademarks and/or product names of Thermo Fisher Scientific. The following are registered trademarks in the United States and other countries: Microsoft, Excel, and Windows are registered trademarks of Microsoft Corporation in the United States and other countries.
Page 3: Table Of Contents
Maintenance Supplies and Tools ........3 Configuring the TSQ 8000 Evo System ....... 4 Powering On the TSQ 8000 Evo System .
Page 4 Investigating Power Supply Issues ........95 TSQ 8000 Evo system does not power on......95 TSQ 8000 Evo system powers on temporarily and trips the circuit breaker.
Page 5 An air leak has been detected........101 TSQ 8000 Evo Tune reports an error while saving a Tune file... 102 Contacting Technical Support.
Page 6 Anode Feedthrough......... . . 245 Reinstalling the TSQ 8000 Evo System Software ..... . 248 Updating the Firmware on the Instrument .
Page 7 Probe Controller ..........398 Thermo Scientific TSQ 8000 Evo Hardware Manual...
Page 9 • Direct Probe Controller (DPC) standards: EMC EN 61326-1:2006. Safety IEC 61010-1:2001, IEC 61010-2-081:2001 • ISQ standards: EMC EN 61326-1:2006. Safety IEC 61010-1:2001, IEC 61010-2-081:2001 • TSQ 8000 and TSQ 8000 Evo standards: EMC EN 61326-1:2006. Safety IEC 61010-1:2001, IEC 61010-2- 081:2001 Low Voltage Safety Compliance...
Page 10 Notice on Lifting and Handling of Thermo Scientific Instruments For your safety, and in compliance with international regulations, the physical handling of this Thermo Fisher Scientific instrument requires a team effort to lift and/or move the instrument. This instrument is too heavy and/or bulky for one person alone to handle safely.
Page 11 WEEE Compliance This product is required to comply with the European Union’s Waste Electrical & Electronic Equipment (WEEE) Directive 2002/96/EC. It is marked with the following symbol: Thermo Fisher Scientific has contracted with one or more recycling or disposal companies in each European Union (EU) Member State, and these companies should dispose of or recycle this product.
Page 12 Conformité DEEE Ce produit doit être conforme à la directive européenne (2002/96/EC) des Déchets d'Equipements Electriques et Electroniques (DEEE). Il est marqué par le symbole suivant: Thermo Fisher Scientific s'est associé avec une ou plusieurs compagnies de recyclage dans chaque état membre de l’union européenne et ce produit devrait être collecté...
Page 13: Preface
• Contacting Us About Your System Thermo Scientific systems provide the highest caliber gas chromatography/mass spectrometry (GC/MS) instrumentation available on today’s market. GC/MS represents a combination of two powerful analytical techniques: GC, which acts as a separation technique, and MS, which acts as a detection technique. Complex mixtures of individual compounds can be injected into the GC, either manually or by an autosampler and then separated for presentation to the MS.
Page 14: Related Documentation
 To open Help • From the TSQ 8000 Evo window, choose Help > TSQ 8000 Evo Help. • If available for a specific window or dialog box, click Help or press the F1 key for information about setting parameters.
Page 15: System Requirements
Preface System Requirements System Requirements Your TSQ 8000 Evo data system must meet these minimum requirements. System Requirements Hardware • 2.4 GHz processor with 4 GB RAM • DVD/CD-ROM drive • Resolution display 1280 × 1024 (XGA) • 250 GB hard drive •...
Page 16: Safety Symbols And Signal Words
This damage might not be covered under the standard warranty. LIFTING HAZARD: Indicates that a physical injury could or might occur if two or more people do not lift an object. TSQ 8000 Evo Hardware Manual Thermo Scientific...
Page 17: Hydrogen Safety Precautions
Before you begin using hydrogen, you should conduct a risk assessment based on the quantity of hydrogen to be used and the conditions of your laboratory. You should ask yourself: “What hydrogen hazards associated with this project are most likely to occur?” Thermo Scientific TSQ 8000 Evo Hardware Manual xvii...
Page 18 • There should also be contingency plans in place should an incident occur. • The site emergency response team, as well as the local fire department, should know the location of all hydrogen storage tanks. xviii TSQ 8000 Evo Hardware Manual Thermo Scientific...
Page 19: Using Hydrogen With Tsq 8000 Evo
Using Hydrogen with TSQ 8000 Evo To use hydrogen with the TSQ 8000 Evo, you must always shut off the GC carrier gas before venting or turning off the TSQ 8000 Evo. There are three hydrogen safety screws on the TSQ 8000 Evo that must be in place.
Page 20 If a hydrogen cylinder or hydrogen generation system is located within immediate reach, a separate point-of-use shutoff valve is usually not necessary. Line regulators that have their source away from the point of use should have a manual shutoff valve near the point of use. TSQ 8000 Evo Hardware Manual Thermo Scientific...
Page 21: Purchasing Hydrogen
Properly Storing Hydrogen Storing and handling compressed hydrogen gas and cryogenic liquid hydrogen present potential health and safety hazards. Using proper storage and handling techniques is essential to maintaining a safe work environment. Thermo Scientific TSQ 8000 Evo Hardware Manual...
Page 22 • As liquid hydrogen systems also have a cryogenic hazard, additional safety considerations for the use of cryogenic liquids might be necessary. xxii TSQ 8000 Evo Hardware Manual Thermo Scientific...
Page 23: Hydrogen Safety Codes, Standards And References
• NFPA 55, Standard for the Storage, Use, and Handling of Compressed Gases and Cryogenic Fluids in Portable and Stationary Containers, Cylinders, and Tanks, 2005 Edition • NFPA 68, Standard on Explosion Protection by Deflagration Venting • NFPA 70, National Electrical Code Thermo Scientific TSQ 8000 Evo Hardware Manual xxiii...
Page 24: Hazardous Substances Precautions
When working with biohazardous materials, you are responsible for fulfilling the following mandatory requirements: • Providing instructions on how to safely handle biohazardous material. • Training operators must to be aware of potential hazards. xxiv TSQ 8000 Evo Hardware Manual Thermo Scientific...
Page 25: Venting Toxic Gases
Go to www.thermoscientific.com/wps/portal/ts/contactus.  To suggest changes to documentation or to Help • Fill out a reader survey online at www.surveymonkey.com/s/PQM6P62. • Send an e-mail message to the Technical Publications Editor at techpubs-austin@thermofisher.com. Thermo Scientific TSQ 8000 Evo Hardware Manual...
Page 27: Performing Routine Maintenance
Performing Routine Maintenance This chapter describes how to perform routine maintenance on the TSQ 8000 Evo system. Keeping your system in good working condition increases laboratory productivity and helps you get the most out of the instrument. Contents • Maintenance Supplies and Tools •...
Page 28 The foreline pump must be replaced if it seizes There are many more components of the TSQ 8000 Evo system that do not require routine maintenance, but may need to be replaced if there is a problem with the instrument. To replace components not listed in this chapter, refer to Chapter 3: Advanced Troubleshooting.
Page 29: Maintenance Supplies And Tools
Cleanroom Gloves. See the TSQ 8000 Evo Spare Parts Guide for ordering information In addition to the MS Toolkit, you can also purchase a TSQ 8000 Evo Screw Kit, which includes extra screws, nuts, and standoffs. Refer to the TSQ 8000 Evo Spare Parts Manual for ordering information.
Page 30: Configuring The Tsq 8000 Evo System
Configuring the TSQ 8000 Evo System Configuring the TSQ 8000 Evo System When you receive your TSQ 8000 Evo system, a Field Service Engineer will configure the system for you. However, if you need to reconfigure your system, follow these steps: 1.
Page 31 2. Connect all the cables to the computer, keyboard, mouse, monitor, and printer (if applicable). 3. Connect the handshaking cable to the GC and to the TSQ 8000 Evo instrument’s GC Start connector. 4. Connect the computer and monitor electrical cables to the wall outlet.
Page 32 Note Condition the column before installing it on the mass spectrometer. 18. Make sure the TSQ 8000 Evo instrument’s power switch is in the Off (down) position. 19. Connect the TSQ 8000 Evo instrument’s electrical cable to the AC Input connector on the mass spectrometer and to the wall outlet.
Page 33: Powering On The Tsq 8000 Evo System
Performing Routine Maintenance Powering On the TSQ 8000 Evo System Powering On the TSQ 8000 Evo System To power-on the TSQ 8000 Evo system: 1. Install the GC column if you have not already done so (see Replacing a Column).
Page 34 Performing Routine Maintenance Powering On the TSQ 8000 Evo System 5. Check the lights on the front of the instrument to make sure it is ready for use. Figure 3. Using the Lights on the TSQ 8000 Evo Instrument Vacuum Busy Power Heaters •...
Page 35 7. Check the status of the vacuum on the TSQ 8000 Evo Dashboard. Within 10 minutes of powering on the instrument, the vacuum should read OK. 8. Check the heater status on the TSQ 8000 Evo Dashboard. If the ion source is not set to the desired temperature, click the Instrument Control button and change the temperature.The temperature set point will change when the send button is pressed.
Page 36: Powering Off The Tsq 8000 Evo System
Once the turbomolecular pump reaches 50% rpm, the foreline pump powers off, and you may vent the system. 4. When the TSQ 8000 Evo system’s temperatures and pumps are ready for shutdown, the vacuum light on the front of the instrument will start blinking rapidly.
Page 37 8. Power-off all the remaining instruments. Refer to their user documentation for specific instructions. CAUTION If you need to work inside the TSQ 8000 Evo instrument, disconnect it from the electrical outlet. Be sure to reconnect it to the AC Input connector on the back of the instrument after finishing your work and closing the instrument.
Page 38: Replacing A Column
Note If you are running samples, stop the acquisition before powering off the system. 1. Cool down the GC oven and injector. See the GC documentation for information. 2. Open the TSQ 8000 Evo Dashboard and click Shut Down. During the shutdown procedure the vacuum and heaters lights will remain off. Once the procedure is complete and the instrument is ready to be powered off, the power light will turn orange and start blinking rapidly.
Page 39 Remove the notched septum from the column. 8. Set up the GC parameters: a. Set the oven and injector temperature to 50 °C (122 °F). b. Set the carrier gas flow to 1.0 mL/min. Thermo Scientific TSQ 8000 Evo Hardware Manual...
Page 40 Repeat the leak check until no leaks are indicated. 10. Calibrate the carrier gas flow (column evaluation): a. Carefully push the capillary column end into the flowmeter section of the column flowmeter connector. TSQ 8000 Evo Hardware Manual Thermo Scientific...
Page 41 Fix any issues found and rerun column evaluation until an appropriate K-factor is achieved.e a leak in the system, while a K-factor that is too high might indicate a blockage. 11. Disconnect the column flowmeter: a. Disconnect the column from the column flowmeter connector. Thermo Scientific TSQ 8000 Evo Hardware Manual...
Page 42 13. Connect the column to the transfer line: a. Lower the oven temperature and allow it to cool. b. If the TSQ 8000 Evo system is running, shut down and vent it. See Powering Off the TSQ 8000 Evo System for instructions.
Page 43 Using your fingers or a 1/4” wrench, tighten the transfer line nut until the column is held in place lightly. Using your fingers or a 1/4 in. wrench, tighten the transfer line nut until the column is held in place lightly. Figure 10. Column Measuring Tool Thermo Scientific TSQ 8000 Evo Hardware Manual...
Page 44 Note If you are using a Siltite ferrule, follow the instructions that come with Siltite ferrules. If you are using a graphite/vespel ferrule, they require conditioning to ensure a leak-tight seal. See the TSQ 8000 Evo Spare Parts Guide for information about ordering these ferrules.
Page 45 15. Restore working conditions. a. Raise the oven temperature to the initial temperature that you will use. b. Turn on vacuum compensation on the GC. c. Power on the TSQ 8000 Evo instrument. See Powering On the TSQ 8000 Evo System for instructions.
Page 46: Maintaining The Foreline Pump
Always plug the foreline pump power cable into the System Mech Pump connector on the rear of the TSQ 8000 Evo instrument and never into a wall outlet. This prevents the foreline pump from operating when the instrument is powered off.
Page 47: Checking The Oil In The Foreline Pump
GC to prevent the buildup of hydrogen in the vacuum manifold. 1. Click the Shut Down button on the TSQ 8000 Evo Dashboard. 2. Click the Yes button to continue the shutdown process. The heaters and turbomolecular pump power off.
Page 48 Maintaining the Foreline Pump 3. Reach over to the left side of the instrument and push down on the power switch to power-off the TSQ 8000 Evo system. Figure 13. Powering Off the TSQ 8000 Evo System Vacuum Interlock Shield Power Switch Vent Valve Knob 4.
Page 49: Purging Gas From The Oil In The Foreline Pump
16. Reconnect the optional mechanical pump to the instrument. 17. Power-on the TSQ 8000 Evo system. 18. Purge the foreline pump for 10 minutes using the gas ballast to remove excess gases from the new oil.
Page 50 WARNING If you are using hydrogen as a carrier gas, you must cool down and shut off the GC to prevent the buildup of hydrogen in the vacuum manifold 1. Click the Shut Down button on the TSQ 8000 Evo Dashboard. 2. Click the Yes button to continue the shutdown process.The heaters and turbomolecular pump power off.
Page 51 17. Reconnect the foreline vacuum hose. 18. Reconnect the foreline pump power cable into the System Mech Pump connector on the back of the TSQ 8000 Evo instrument. 19. Reconnect the optional mechanical pump to the instrument. 20. Twist the vent valve one and a half times in a clockwise direction or until the o-ring is fully engaged.
Page 52 23. Purge the foreline pump for 10 minutes by using the gas ballast to remove excess gases from the new oil. See Purging Gas from the Oil in the Foreline Pump for more information. TSQ 8000 Evo Hardware Manual Thermo Scientific...
Page 53: Removing The Ion Source Cartridge For Cleaning
For this reason, clean room gloves are strongly recommended when handling the ion source. We recommend Cardinal Health CP100 Nitrile Cleanroom Gloves. See the TSQ 8000 Evo Spare Parts Guide for ordering information.
Page 54: Removing The Ion Source Cartridge
After you reattach the knob, press the Evacuate button to remove any air inside the vacuum interlock. TSQ 8000 Evo Hardware Manual Thermo Scientific...
Page 55 3. Grasp the handle of the source exchange tool in one hand and use your other hand to pull the metal barrel out and away from the handle so that tool is fully extended. 4. Attach the source exchange tool to the front of the instrument. Thermo Scientific TSQ 8000 Evo Hardware Manual...
Page 56 Twist and push the stainless steel barrel to the right until it clicks into place under the screw at the top of the slot. Figure 18. Twisting the Tool Into Place Alignment Groove TSQ 8000 Evo Hardware Manual Thermo Scientific...
Page 57 6. Twist, then loosen the top part of the vacuum interlock handle to allow the entire handle to swing up and down. This handle controls the interior ball valve, which seals the vacuum chamber. Thermo Scientific TSQ 8000 Evo Hardware Manual...
Page 58 LED will flash on and off. CAUTION INSTRUMENT DAMAGE: Make sure the vacuum interlock handle is all the way up. Otherwise if you insert the tool with the handle down, you can damage the instrument. TSQ 8000 Evo Hardware Manual Thermo Scientific...
Page 59 11. Pull the tool toward you and down the left side of the metal track on the barrel. As you keep pulling it toward you, more and more of the barrel will be exposed. You may Thermo Scientific TSQ 8000 Evo Hardware Manual...
Page 60 12. Once you reach the end of the track (when the back line at the end of the barrel is uncovered by the black handle), twist the handle to the left to lock it into place. Figure 23. Locking the Tool in Place Note: Tool Rotated Left TSQ 8000 Evo Hardware Manual Thermo Scientific...
Page 61 16. Remove the tool from the instrument. Thermo Scientific TSQ 8000 Evo Hardware Manual...
Page 62 Performing Routine Maintenance Removing the Ion Source Cartridge for Cleaning Figure 25. Removing the Tool from the Instrument TSQ 8000 Evo Hardware Manual Thermo Scientific...
Page 63 Figure 26. Exposing the Ion Source Cartridge Ion Source Cartridge 19. Invert the source exchange tool so that the barrel is pointed toward the floor. Figure 27. Inverting the Tool Ion Source Cartridge Thermo Scientific TSQ 8000 Evo Hardware Manual...
Page 64 Performing Routine Maintenance Removing the Ion Source Cartridge for Cleaning 20. Slide the source holder, which is in the TSQ 8000 Evo Toolkit, onto the end of the ion source cartridge. The opening of the source holder is designed to accommodate the handles of the ion volume.
Page 65: Disassembling The Ion Source Cartridge
Repeller Repeller 2. Set the components on a clean work surface. 3. Separate the repeller nut, ion volume-repeller insulator, and repeller. 4. Clean the ion source cartridge as instructed in Cleaning Durable Components. Thermo Scientific TSQ 8000 Evo Hardware Manual...
Page 66: Reassembling The Ion Source Cartridge
3. Align the long tooth of lens 3/RF lens with the notch on the bottom of the sleeve and drop the lens into the sleeve. Figure 32. Inserting Lens 3/RF Lens into the Source Sleeve Long Tooth on Lens 3/RF Lens Tooth Fits Here TSQ 8000 Evo Hardware Manual Thermo Scientific...
Page 67 5. With the longer teeth of lens 1 facing down toward lens 2, align the larger metal section of lens 1 with the sleeve window and let it fall into place. Figure 34. Inserting Lens 1 into the Source Sleeve Larger Metal Longer Teeth Section of Lens 1 Sleeve Window Thermo Scientific TSQ 8000 Evo Hardware Manual...
Page 68 Figure 35. Inserting the Ion Volume into the Source Sleeve Handles Fit Ion Volume Here Handles Lens 1 Gap Note The ion volume handles are different sizes and will only fit into the sleeve one way. 7. Tighten the repeller nut. TSQ 8000 Evo Hardware Manual Thermo Scientific...
Page 69 Figure 36. Inserting the Repeller into the Source Sleeve Large Flat End of Repeller 9. Slide the repeller spring onto the repeller. Figure 37. Inserting the Repeller Spring into the Sleeve Repeller Spring Thermo Scientific TSQ 8000 Evo Hardware Manual...
Page 70: Reinserting The Ion Source Cartridge
IMPORTANT If you try to attach the ion source cartridge to the tool by inverting it, the components will likely fall, so make sure you are working over a table. Otherwise, you may have to stop and clean the components again. TSQ 8000 Evo Hardware Manual Thermo Scientific...
Page 71 Using too much force when inserting the ion source cartridge into the barrel can cause damage. Thermo Scientific TSQ 8000 Evo Hardware Manual...
Page 72 Figure 41. Removing the Source Holder Tip When the source exchange tool is inverted, the source should stay attached. If this does not happen, the source will not insert correctly into the instrument. TSQ 8000 Evo Hardware Manual Thermo Scientific...
Page 73 9. Insert the barrel end of the ion cartridge tool into the vacuum interlock and twist it to the right to lock it into position. Be sure the black handle remains in the locked position. Figure 42. Evacuating the Instrument Evacuate Button Thermo Scientific TSQ 8000 Evo Hardware Manual...
Page 74 IMPORTANT Make sure you take the correct track on the tool or the ion volume will disassemble inside the instrument. If that happens, the tool will get stuck and you will have to shut down, vent the TSQ 8000 Evo instrument, and manually remove the source cartridge through the top of the instrument.
Page 75 14. Twist the handle of the source exchange tool to the right and pull it back toward you and down the right side of the barrel’s metal track until the line at the end of the track appears. Figure 44. Pulling the Tool Down the Right Track Thermo Scientific TSQ 8000 Evo Hardware Manual...
Page 76 19. For optimal performance, wait at least 30 minutes for the ion source to heat up to the same temperature as the inside of the instrument. Otherwise, the masses or intensities may drift during operation. TSQ 8000 Evo Hardware Manual Thermo Scientific...
Page 77: Maintaining The Calibration Gas Module
Maintaining the Calibration Gas Module Maintaining the Calibration Gas Module The calibration gas module on the TSQ 8000 Evo mass spectrometer is very easy to maintain. It is inside the front door of the instrument, and you only refill the calibration gas reservoir every one to two years.
Page 78: Refilling The Calibrant Reservoir
To refill the calibrant reservoir: Note It is not necessary to vent the instrument to perform this operation 1. Open the front door of the TSQ 8000 Evo instrument. 2. Twist the calibrant reservoir cover counter-clockwise and remove it from the calibration gas controller.
Page 79 Be sure liquid does not get into the controller when you reattach the reservoir. 5. Reattach the cover to the calibration gas controller. 6. Close the front door of the instrument. Thermo Scientific TSQ 8000 Evo Hardware Manual...
Page 80: Replacing A Dual Filament
Also, if one of the filaments has burned out, it may be time to replace it. Note See the TSQ 8000 Evo Spare Parts Guide for information about ordering a new filament.
Page 81 4. Reach over to the left side of the instrument and push down on the power switch to power-off the TSQ 8000 Evo system. Figure 48. Powering Off and Venting the TSQ 8000 Evo System Power Switch Top Cover Panel Screw...
Page 82 10. Use a T20 Torxhead screwdriver to remove the four screws around the manifold door. Figure 49. Opening the Manifold Door Screws 11. Pull the manifold door out to open. Once the alignment pins are clear of the thumbscrews, swing the manifold door open. TSQ 8000 Evo Hardware Manual Thermo Scientific...
Page 83 We recommend Cardinal Health CP100 Nitrile Cleanroom Gloves. See the TSQ 8000 Evo Spare Parts Guide for ordering information. 13. Look through the top of the instrument and use a clean T10 Torxhead screwdriver to loosen the screw holding the filament retaining clip in place.
Page 84 Figure 51. Disconnecting the Filament Source Interface Board Filament Filament Screw Retaining Spring 14. Disconnect the filament board and wires from the source interface board. Figure 52. Disconnecting the Filament Board and Wires Filament Board and Wires TSQ 8000 Evo Hardware Manual Thermo Scientific...
Page 85 Do not apply excess force to the thumbscrews or components may be damaged. Note Once the manifold door is closed, ensure the filament wires do not contact the metal surface of the door. Thermo Scientific TSQ 8000 Evo Hardware Manual...
Page 86 23. Twist the vent valve one and a half times in a clockwise direction to close it or until tight. 24. Reach over to the left side of the instrument and pull up on the power switch to power-on the TSQ 8000 Evo system. TSQ 8000 Evo Hardware Manual...
Page 87: Replacing The Electron Multiplier
Preface for more information. 2. Shut down the TSQ 8000 Evo system using the software. See the TSQ 8000 Evo User Guide for more information. 3. Click the Yes button to continue the shutdown process. The heaters and the turbomolecular pump power off.
Page 88 7. Look behind the right side of the vacuum interlock shield and twist the vent valve knob one and a half times in a counter-clockwise direction to open the vent. 8. Wait five minutes for the TSQ 8000 Evo instrument to vent. CAUTION - INSTRUMENT DAMAGE Do not proceed until the instrument is vented or pieces of the column or ferrule might blow into the instrument.
Page 89 13. Use a T20 Torxhead screwdriver to remove the four screws at each corner of the electron multiplier plate. CAUTION - ELECTRICAL HAZARD Avoid dropping screws between chassis and side cover or board. If you drop a screw, find it before powering the instrument on again. Thermo Scientific TSQ 8000 Evo Hardware Manual...
Page 90 Performing Routine Maintenance Replacing the Electron Multiplier Figure 57. Disconnecting the Electron Multiplier Plate Electron Multiplier Plate Screws 14. Lift the electron multiplier plate out of the vacuum manifold. TSQ 8000 Evo Hardware Manual Thermo Scientific...
Page 91 We recommend Cardinal Health CP100 Nitrile Cleanroom Gloves. See the TSQ 8000 Evo Spare Parts Guide for ordering information 19. Make sure the electron multiplier fits snugly. 20. Reconnect the stainless steel wire to the gold connector.
Page 92 Figure 60. Reconnecting the Electron Multiplier Cables Electrometer Board Cable Large Feedthrough Cables Electrometer Shield Electron Multiplier Plate 25. Reattach the top cover panel and tighten the screw holding the top cover panel in place. TSQ 8000 Evo Hardware Manual Thermo Scientific...
Page 93 Instead, reach around the left side or go to the back of the instrument and flip up the power switch. 34. Open TSQ 8000 Evo Auto Tune on the TSQ 8000 Evo Dashboard. 35. Run any tune that sets the gain of the electron multiplier to 3 x 10...
Page 94: Cleaning Durable Components
Cleaning the other components are not part of the expected maintenance. To clean durable components of the TSQ 8000 Evo instrument, you will need the following cleaning supplies: • Acetone, reagent grade (or other suitable polar solvent) •...
Page 95 Twist the sharpened end of the swab into the electron entrance hole on the CI ion volume to clean out debris. You may need to use several swabs before the electron entrance hole is clear of debris. Figure 61. Cleaning the CI Ion Volume Electron Entrance Hole Thermo Scientific TSQ 8000 Evo Hardware Manual...
Page 96 Repeat until the water is clear. 5. Use forceps to immediately transfer the components to a clean beaker of acetone. TSQ 8000 Evo Hardware Manual Thermo Scientific...
Page 97 7. Wearing gloves, blow clean, dry gas on the components to remove the acetone. Note Acetone should not be allowed to dry on the part. It will leave a residue that may affect instrument performance. Thermo Scientific TSQ 8000 Evo Hardware Manual...
Page 98: Cleaning Delicate Components
• Source magnets • Top (glass) manifold cover Note Cleaning these components is not part of the expected maintenance. To clean delicate components of the TSQ 8000 Evo instrument, you will need the following cleaning supplies: • Applicators, cotton-tipped • Deionized water •...
Page 99 3. Rinse the components with methanol. Using forceps, dip the components in a beaker of methanol. Change the methanol if it becomes cloudy. Do not soak or sonicate the components. 4. While still wearing gloves, use clean, dry gas to blow the methanol off the components. Thermo Scientific TSQ 8000 Evo Hardware Manual...
Page 100: Cleaning The Filters
Cleaning the Filters To clean the filters and fan filter on the TSQ 8000 Evo instrument: Note If your filters wear out or get damaged, refer to the TSQ 8000 Evo Spare Parts Guide for information about ordering new ones.
Page 101 10. Wash the filters in soap and water. 11. Let the filters dry. 12. Reattach the filters. 13. Replace the turbo cooling fan filter cover. 14. Close the front door of the instrument. Thermo Scientific TSQ 8000 Evo Hardware Manual...
Page 103: Troubleshooting
8000 Evo mass spectrometer. All of these issues are related to hardware, but your instrument or software will alert you to them. For issues that you discover while reviewing your data, see the Troubleshooting section of the TSQ 8000 Evo User Guide. Contents •...
Page 104: Using Diagnostics
Using Diagnostics Using Diagnostics If your TSQ 8000 Evo system is running poorly or suspiciously, you can run software diagnostics to detect the problem and find a solution. Diagnostics tests electronic circuits and reports whether the circuits pass or fail. However, problems in sensitivity due to misalignment, dirty components, or improper tuning are not detected by the software.
Page 105 2. Select an existing tune type and click the Copy button. Figure 64. Copying a Tune Type 3. Name your diagnostic tune type. Figure 65. Naming Your Diagnostic Tune Type 4. Select the Diagnostics Only option in the Type field. Thermo Scientific TSQ 8000 Evo Hardware Manual...
Page 106 Troubleshooting Using Diagnostics 5. Click the Diagnostics tab and select the types of diagnostics you would like to perform on your instrument. Figure 66. Selecting Types of Diagnostics 6. Click Save. TSQ 8000 Evo Hardware Manual Thermo Scientific...
Page 107: Running A Diagnostic Tune
Troubleshooting Using Diagnostics Running a Diagnostic Tune To run a diagnostic tune: 1. Click Auto Tune on the TSQ Series Dashboard to run diagnostics. Figure 67. Running an Automatic Tune Thermo Scientific TSQ 8000 Evo Hardware Manual...
Page 108 2. Select the diagnostics tune type you created and click Start. Figure 68. Running Diagnostics 3. Click View Tune Report on the TSQ 8000 Evo Dashboard to view the diagnostic results. 4. Click the Report Options button in the upper right corner of the window.
Page 109: Investigating Communication Issues
Open the Instrument Configuration utility and verify the GC methods and configuration. Make sure the Remote Start cable is properly connected to the Generic/HS port on the GC and to the GC Start port on the TSQ 8000 Evo system.
Page 110 On a FOCUS GC, use the Keypad button in Xcalibur. • Press the Home button. • Scroll down to the <others> option and press <ENTER>. • Scroll down to <Configuration> and press <ENTER>. TSQ 8000 Evo Hardware Manual Thermo Scientific...
Page 111: Sample Data Are Not Acquired
Make sure the Remote Start cable is properly connected to the GC. Make sure the End Run Time is set properly in the TSQ 8000 Evo Instrument Setup file. Add more disk space to the computer by backing up and removing files.
Page 112: Investigating Contamination Issues
WARNING ELECTRICAL SHOCK HAZARD: When troubleshooting any issue that requires removing a cover on the TSQ 8000 Evo mass spectrometer, you should power-off and vent the instrument to avoid harming yourself. TSQ 8000 Evo Hardware Manual...
Page 113: Chemical Noise Is At M/Z 429, 355, 281
Table 7. Possible Remedies for Chemical Noise at m/z 429, 355, 281 Condition the column. It is best to condition the column outside of the TSQ 8000 Evo mass spectrometer so the contaminants can escape into the air instead of the instrument.
Page 114 Table 11. Possible Remedies for Solvent Contamination You may have a leak that is allowing solvent vapors to get into the TSQ 8000 Evo instrument. Use a spray gas, such as Tetrafluoethane, to check for leaks and then fix them. See Investigating Vacuum Issues for details.
Page 115: Investigating Filament And Lens Control Issues
Investigating Filament and Lens Control Issues Investigating Filament and Lens Control Issues Filament Check diagnostics can test the filament and lenses of the TSQ 8000 Evo mass spectrometer. Handle the lenses with care. Damaged lenses may cause short circuits, which may damage the lens drivers.
Page 116: Investigating Temperature Issues
Investigating Temperature Issues Investigating Temperature Issues The ion source and transfer line are heated zones in the TSQ 8000 Evo instrument. The lens/source heater is controlled by the TSQ 8000 Evo mass spectrometer and the transfer line heater is controlled by the GC.
Page 117: Lens/Source Heater Does Not Heat
Lens/source heater does not heat. Table 15. Possible Remedies when Lens/source Heater does not Heat Make sure the TSQ 8000 Evo system and computer are properly connected. Check the vacuum status as the heaters will not turn on until vacuum status reads OK.
Page 118: Investigating Vacuum Issues
Investigating Vacuum Issues Investigating Vacuum Issues When you run Vacuum System Check diagnostics on the TSQ 8000 Evo mass spectrometer, the Xcalibur software checks the vacuum system. Vacuum issues may also be found when you run Leak Check diagnostics. Your instrument or software may indicate the following types of issues.
Page 119: An Air Leak Is Detected
• Clean dust or debris from the top cover O-ring. If you do not find a leak, turn on the TSQ 8000 Evo system in full-scan mode. Click Custom Spectrum on the TSQ 8000 Evo Dashboard. Set the Scan Type to Full Scan and Start/End mass to cover the characteristic ions for the compressed gas you are using. Most compressed gases have ions between m/z 35 and 100.
Page 120: Turbomolecular Pump Shuts Off While In Use
Run Leak Check diagnostics to look for leaks and address them. Excessive gas flow may cause the pump to overheat. Ensure the temperature of the lab environment is 15-35 °C. Make sure the combined flow of carrier gas and CI reagent gas to the TSQ 8000 Evo is less than 10 mL/min. TSQ 8000 Evo Hardware Manual...
Page 121: Investigating Power Supply Issues
TSQ 8000 Evo system does not power on. Table 24. Possible Remedies when TSQ 8000 Evo System does not Power On Make sure the TSQ 8000 Evo instrument’s power cable is properly connected to the instrument and electrical outlet. Verify that the electrical outlet is functioning properly.
Page 122: Investigating Rf/Dc Issues
Table 28. Possible Remedy if RF/DC System Check Diagnostic Fails Use TSQ 8000 Evo Tune to tune the RF system. If the RF system will not tune, contact Technical Support. Make sure the rod driver board is properly installed and undamaged. Replace it, if necessary. See...
Page 123: Investigating Sensitivity Issues
Investigating Sensitivity Issues Investigating Sensitivity Issues When you run Detector Check diagnostics on the TSQ 8000 Evo system, the Xcalibur software checks for noise on the electrometer, multiplier, dynode and RF board. Sensitivity issues are usually the result of an air leak, dirty components, or contamination. Sometimes sensitivity issues can be caused by simple to fix problems such as the carrier gas tank running out or a sample not being injected into the GC.
Page 124: Poor Sensitivity Or Sudden Loss In Sensitivity
If you recently performed maintenance on your ion source, remove the ion source, verify that it is assembled correctly, and reinsert it into the TSQ 8000 Evo. Make sure the GC column does not extend into the ion source. Use the column measuring tool to ensure the column is the correct length.
Page 125: Investigating Stability Issues
WARNING ELECTRICAL SHOCK HAZARD: When troubleshooting any issue that requires removing a cover on the TSQ 8000 Evo mass spectrometer, you should power-off and vent the instrument to avoid harming yourself. Mass assignment is unstable.
Page 126: Investigating Tuning Issues
WARNING ELECTRICAL SHOCK HAZARD: When troubleshooting any issue that requires removing a cover on the TSQ 8000 Evo mass spectrometer, you should power-off and vent the instrument to avoid harming yourself. TSQ 8000 Evo Hardware Manual...
Page 127: Tune Is Interrupted
Allow contaminants to pump away so they do not interfere with calibration gas ions. Calibrate by running an automatic tune. An air leak has been detected. Table 39. Possible Remedy for Air Leaks Check the system for air leaks and address them. Thermo Scientific TSQ 8000 Evo Hardware Manual...
Page 128: Tsq 8000 Evo Tune Reports An Error While Saving A Tune File
TSQ 8000 Evo Tune reports an error while saving a Tune file. Table 40. Possible Remedy if Errors are Reported While Saving a Tune File Check that there is sufficient space on the hard drive to save a new Tune file. If there is not enough space to save a new Tune file, copy old...
Page 129: Contacting Technical Support
Support. Be sure to reference the model number and serial number of your instrument when contacting them. Every TSQ 8000 Evo system ships with a label inside the front door that lists the model number and serial number. Figure 69. Identifying Your TSQ 8000 Evo Instrument...
Page 130 Troubleshooting Contacting Technical Support TSQ 8000 Evo Hardware Manual Thermo Scientific...
Page 131: Advanced Troubleshooting
Advanced Troubleshooting This chapter describes the TSQ 8000 Evo system’s components that do not require routine maintenance, but troubleshooting may indicate they need to be replaced. Contents • Replacing Components of the Analyzer • Replacing Components of the Ion Source •...
Page 132: Replacing Components Of The Analyzer
Q1 quad assembly, the Q3 quad assembly, and the collision cell assembly. Figure 70. Replaceable Components of the Analyzer Tray Quadrupole 3 Quadrupole 1 Ion Guide Collision Cell Analyzer Ion Source Assembly Tray TSQ 8000 Evo Hardware Manual Thermo Scientific...
Page 133: Analyzer Tray
Preface for more information. 4. Shut down the TSQ 8000 Evo system using the software. See the TSQ 8000 Evo User Guide for more information. 5. Click the Yes button to continue the shutdown process. The heaters and the turbomolecular pump power off.
Page 134 9. Look behind the right side of the vacuum interlock shield and twist the vent valve knob one and a half times in a counter-clockwise direction to open the vent. 10. Wait five minutes for the TSQ 8000 Evo instrument to vent. CAUTION - INSTRUMENT DAMAGE Do not proceed until the instrument is vented or pieces of the column or ferrule might blow into the instrument.
Page 135 4. Set the glass covers on a surface where they will not be scratched or contaminated. Protect the glass and any other manifold components from dust accumulation. Wear cleanroom gloves when touching the glass. See the TSQ 8000 Evo Spare Parts Guide for information about ordering cleanroom gloves.
Page 136 Front 4-pin Wires Connector Ion Guide Wires 6. Disconnect the four wires that go to the collision cell and quadrupole 3. These wires are attached to the rear 4-pin feedthrough in the vacuum manifold. TSQ 8000 Evo Hardware Manual Thermo Scientific...
Page 137 Note Remove the screws completely so that they do not scratch the manifold when you close the door. Figure 76. Opening the Manifold Door Screws 9. Open the manifold door and slide the filament board and wires off the pins on the source interface board Thermo Scientific TSQ 8000 Evo Hardware Manual...
Page 138 CAUTION - INSTRUMENT DAMAGE Do not scratch any of the sealing surfaces. Be especially careful when the source interface board reaches the o-ring surface. TSQ 8000 Evo Hardware Manual Thermo Scientific...
Page 139 3. Remove the Q3 quad assembly and Q3 exit lens assembly from the tray. 4. Detach the Q3 exit lens assembly from the Q3 quad assembly. 5. Set the Q3 quad assembly and Q3 exit lens assembly on a clean work surface. Thermo Scientific TSQ 8000 Evo Hardware Manual...
Page 140 Figure 81. Removing the Collision Cell and Q1 Quad Assembly from the Analyzer Tray Q1 Quad Assembly Q1 Entrance Lens Endcap Collision Cell Assembly Screw to Screw to Q1 Entrance Lens Screw to Axial Field Grounding Endcap Screws to Analyzer Tray Wire Wire Analyzer Tray TSQ 8000 Evo Hardware Manual Thermo Scientific...
Page 141 IMPORTANT Be careful not to drop the MACOR ceramic plate. See Figure 83. It is fragile. Figure 83. Removing the Ion Source from the Analyzer Tray MACOR Ceramic Plate Screws 16. Remove the source block from the analyzer tray and set it aside. Thermo Scientific TSQ 8000 Evo Hardware Manual...
Page 142 Slightly tighten each screw several times going from one to another until all are securely tightened. TSQ 8000 Evo Hardware Manual Thermo Scientific...
Page 143 Tip The endcaps have cutouts that you should use to check to be sure the ceramics are aligned properly before attaching the two screws. Figure 86. Replacing the Collision Cell and Quadrupole 3 in the Analyzer Tray Q3 Exit Lens Assembly Q3 Quad Assembly Collision Cell Assembly Screws Thermo Scientific TSQ 8000 Evo Hardware Manual...
Page 144 Replacing the Analyzer Tray in the TSQ 8000 Evo Instrument  To replace the analyzer tray in the TSQ 8000 Evo instrument 1. Slide the analyzer tray back into the instrument. Note The analyzer tray will mount on one alignment pin in the back and the transfer line on the right.
Page 145 8. Close the manifold door and reattach the four screws. 9. Reconnect the four wires that connect the rear 4-pin feedthrough to quadrupole 3 and the collision cell assembly. See Figure 75 page 111. Thermo Scientific TSQ 8000 Evo Hardware Manual...
Page 146 6. Replace all hydrogen safety screws if you are using hydrogen. 7. Power-on the TSQ 8000 Evo mass spectrometer. 8. If the GC is powered off, power it on and make sure vacuum compensation is on for the carrier gas flowing into the mass spectrometer.
Page 147: Ion Guide
Replacing Components of the Analyzer Ion Guide  To replace the ion guide: Note See the TSQ 8000 Evo Spare Parts Guide for information about ordering this component. 1. Shut down your system by following the steps in “Shutting Down the TSQ 8000 Evo System”...
Page 148 9. Remove the two screws on each side of the Q1 entrance endcap. Figure 92. Removing Screws from the Quadrupole Rod Endcaps Collision Cell Assembly Q1 Entrance Lens and Endcap Screws 10. Remove the Q1 entrance lens endcap and ion guide from the tray. TSQ 8000 Evo Hardware Manual Thermo Scientific...
Page 149 17. Tighten the two T10 screws inside the endcap. Note Make sure the Q1 entrance lens sits flush and centered in the Q1 entrance lens endcap. Thermo Scientific TSQ 8000 Evo Hardware Manual...
Page 150 Slightly tighten each screw several times going from one to another until all are securely tightened. Figure 96. Reattaching Quadrupole 1, the Ion Guide , and the Collision Cell Assembly to the Analyzer Tray Quadrupole 1 Collision Cell Q1 Entrance Assembly Lens Endcap Screws TSQ 8000 Evo Hardware Manual Thermo Scientific...
Page 151 25. Reconnect the Q1 entrance lens wire to the source interface board. 26. Once the components are correctly attached to the analyzer tray, follow the instructions “Replacing the Analyzer Tray in the TSQ 8000 Evo Instrument” page 118 replace the tray in the TSQ instrument.
Page 152: Q1 Entrance Lens And Q1 Entrance Lens Endcap
Q1 Entrance Lens and Q1 Entrance Lens Endcap  To replace the Q1 entrance lens and Q1 entrance lens endcap Note See the TSQ 8000 Evo Spare Parts Guide for information about ordering this component. 1. Shut down your system by following the steps in “Shutting Down the TSQ 8000 Evo...
Page 153 9. Remove the two screws on each side of the Q1 entrance endcap. Figure 101. Removing Screws from the Quadrupole Rod Endcaps Collision Cell Assembly Q1 Entrance Lens and Endcap Screws 10. Remove the Q1 entrance lens endcap and ion guide from the tray. Thermo Scientific TSQ 8000 Evo Hardware Manual...
Page 154 16. Insert Q1 and the collision cell assembly onto the analyzer tray. 17. Hold the collision cell and Q1 in the tray and make sure the quad and ion guide are correctly positioned before tightening the screws on the Q1 entrance lens endcap TSQ 8000 Evo Hardware Manual Thermo Scientific...
Page 155 19. Reattach the two screws on each side of the quadrupole rod endcaps. Tip The endcaps have cutouts that you should use to check to be sure the ceramics are aligned properly before attaching the two screws. Thermo Scientific TSQ 8000 Evo Hardware Manual...
Page 156 21. Reconnect the Q1 entrance lens wire to the source interface board. 22. Once the components are correctly attached to the analyzer tray, follow the instructions “Replacing the Analyzer Tray in the TSQ 8000 Evo Instrument” page 118 replace the tray in the TSQ instrument.
Page 157: Ion Guide Wire Set
Ion Guide Wire Set  To replace the ion guide wires Note See the TSQ 8000 Evo Spare Parts Guide for information about ordering these components. 1. Shut down your system by following the steps in “Shutting Down the TSQ 8000 Evo System”...
Page 158: Q1 Quad, Q3 Quad, And Collision Cell Assemblies
 To replace Q1 quad assembly, the Q3 quad assembly, or the collision cell assembly Note See the TSQ 8000 Evo Spare Parts Guide for information about ordering this component. 1. Shut down your system by following the steps in “Shutting Down the TSQ 8000 Evo...
Page 159 Endcap Screws to Wire Analyzer Tray 10. Slide the Q1 quad assembly away from the Q1 entrance lens and endcap. 11. Replace Q1 if necessary. 12. Slide Q1 back into the Q1 entrance lens endcap. Thermo Scientific TSQ 8000 Evo Hardware Manual...
Page 160 3 and the collision cell assembly are correctly positioned before tightening screws. 15. Reattach the two screws on each side of the quadrupole rod endcaps. Tip Look through the endcaps to be sure the quadrupole ceramics are aligned properly. TSQ 8000 Evo Hardware Manual Thermo Scientific...
Page 161 Collision Cell Assembly Screws 16. Replace the analyzer tray into the instrument by following the instructions in “Replacing the Analyzer Tray in the TSQ 8000 Evo Instrument” page 118. 17. Restart your system by following the instructions in “Restarting the System”...
Page 162: Quad 1 And Quad 3 Wire Sets
Quad 1 and Quad 3 Wire Sets  To replace the quad 1 or quad 3 wire sets Note See the TSQ 8000 Evo Spare Parts Guide for information about ordering this component. 1. Shut down your system by following the steps in “Shutting Down the TSQ 8000 Evo...
Page 163 CAUTION - INSTRUMENT DAMAGE Be careful when removing and inserting the screws on the metal quadrupole rod endcaps. The screws are susceptible to falling between the rods. Figure 114. Attaching the Screws and Washers Correctly Copper Washers Screw Quad Assembly Wire Thermo Scientific TSQ 8000 Evo Hardware Manual...
Page 164 Advanced Troubleshooting Replacing Components of the Analyzer 6. Replace the analyzer tray into the instrument by following the instructions in “Replacing the Analyzer Tray in the TSQ 8000 Evo Instrument” page 118. 7. Restart your system by following the instructions in “Restarting the System”...
Page 165: Q3 Exit Lens Assembly
Q3 Exit Lens Assembly  To replace the Q3 exit lens assembly Note See the TSQ 8000 Evo Spare Parts Guide for information about ordering this component. 1. Shut down your system by following the steps in “Shutting Down the TSQ 8000 Evo System”...
Page 166 7. Reattach the wire to the Q3 exit lens. 8. Replace the analyzer tray into the instrument by following the instructions in “Replacing the Analyzer Tray in the TSQ 8000 Evo Instrument” page 118. 9. Restart your system by following the instructions in “Restarting the System”...
Page 167: Replacing Components Of The Ion Source
If you just need to clean the ion source cartridge, see Cleaning the Ion Source Cartridge. Note See the TSQ 8000 Evo Spare Parts Guide for information about ordering these components. Figure 117. Replaceable Components of the Ion Source Source...
Page 168: Source Heater Block, Lens Heater Block, And Lens/Source Heater
Source Heater Block, Lens Heater Block, and Lens/Source Heater  To replace the source heater block, lens heater block, or lens/source heater Note See the TSQ 8000 Evo Spare Parts Guide for information about ordering these components. WARNING - INSTRUMENT DAMAGE Thermo Fisher Scientific strongly recommends that only trained Thermo Fisher Scientific Field Service Engineers remove and service these components.
Page 169 8. Using a T10 Torxhead to remove the two screws on the mixing chamber and pull the chamber off. 9. Twist and remove the two source-repeller thumbscrews. Figure 120. Removing the Source-Repeller Thumbscrews Source-Repeller Thumbscrews Thermo Scientific TSQ 8000 Evo Hardware Manual...
Page 170 Figure 121. Removing the Thumbscrew-Repeller Spacers Thumbscrew-Repeller Spacers 11. Pull away the repeller plate and remove the insulating spacers. Figure 122. Removing the Repeller Plate and Insulating Spacers Gas Mixing Chamber Repeller Plate Screws Insulating TSQ 8000 Evo Hardware Manual Thermo Scientific...
Page 171 To avoid damage, separate the block from the tray before removing the lens/source heater. Figure 124. Removing the Ion Source from the Analyzer Tray Ion Source Block Wires Thermo Scientific TSQ 8000 Evo Hardware Manual...
Page 172 Replace the lens/source heater if necessary. Figure 125. Disconnecting the Lens/Source Heater Lens/Source Heater Screws and Cone Washers 15. Remove and replace the source heater block if necessary. Figure 126. Replacing the Source Heater Block Source Heater Block TSQ 8000 Evo Hardware Manual Thermo Scientific...
Page 173 20. Reattach the lens/source heater to the new source heater block and set them next to the rest of the ion source. Figure 128. Reattaching the Lens/Source Heater Lens/Source Heater Screws and Washers Thermo Scientific TSQ 8000 Evo Hardware Manual...
Page 174 Figure 129. Sliding the Source Block onto the Analyzer Tray Source Interface Board Source Heater Block Wires 22. Reattach the two screws to the back of the ion source. Figure 130. Reconnecting the Source Block to the Analyzer Tray Screws TSQ 8000 Evo Hardware Manual Thermo Scientific...
Page 175 Figure 131. Reattaching the Gas Mixing Chamber Repeller Plate Gas Mixing Chamber Insulating Spacers Screws 24. Reattach the repeller plate and insulating spacers. 25. Insert the thumbscrew-repeller spacers into a groove in the thumbscrew. Thermo Scientific TSQ 8000 Evo Hardware Manual...
Page 176 Figure 133. Reconnecting the Lens Heater Block Grounding Strap Lens Heater Block Lens Heater Grounding Strap Screw 28. Reconnect the Q1 entrance lens, Q2 entrance lens, and Q3 exit lens wires to the source interface board using a flat-tipped screwdriver. TSQ 8000 Evo Hardware Manual Thermo Scientific...
Page 177 Figure 134. Locating Wires on the Source Interface Board 29. Replace the analyzer tray into the instrument by following the instructions in “Replacing the Analyzer Tray in the TSQ 8000 Evo Instrument” page 118. 30. Restart your system by following the instructions in “Restarting the System”...
Page 178: Source-Repeller Thumbscrews
Replacing Components of the Ion Source Source-Repeller Thumbscrews  To replace the source-repeller thumbscrews: Note See the TSQ 8000 Evo Spare Parts Guide for information about ordering this component. 1. Shut down your system by following the steps in “Shutting Down the TSQ 8000 Evo System”...
Page 179 Thumbscrews 6. Attach new source-repeller thumbscrews to the ion source. 7. Reattach the manifold door and the four screws. 8. Restart your system by following the instructions in “Restarting the System” page 120. Thermo Scientific TSQ 8000 Evo Hardware Manual...
Page 180: Thumbscrew-Repeller Spacers
Replacing Components of the Ion Source Thumbscrew-Repeller Spacers  To replace the thumbscrew-repeller spacers Note See the TSQ 8000 Evo Spare Parts Guide for information about ordering this component. 1. Shut down your system by following the steps in “Shutting Down the TSQ 8000 Evo System”...
Page 181 Also, do not over-tighten the thumbscrews or it may crack the spacers. 6. Reattach the source-repeller thumbscrews to the spacers. 7. Reattach the manifold door and the four screws. 8. Restart your system by following the instructions in “Restarting the System” page 120. Thermo Scientific TSQ 8000 Evo Hardware Manual...
Page 182: Insulating Spacers
Replacing Components of the Ion Source Insulating Spacers  To replace the insulating spacers Note See the TSQ 8000 Evo Spare Parts Guide for information about ordering this component. 1. Shut down your system by following the steps in “Shutting Down the TSQ 8000 Evo System”...
Page 183 Figure 141. Replacing the Source-Repeller Thumbscrews Source-Repeller Thumbscrews 5. Remove the thumbscrew-repeller spacers from the thumbscrews. Figure 142. Replacing the Thumbscrew-Repeller Spacers Thumbscrew-Repeller Spacers 6. Move the locking ring out of the way. Thermo Scientific TSQ 8000 Evo Hardware Manual...
Page 184 11. Reattach the manifold door and the four screws. 12. Reattach the top cover and tighten the top cover panel screw. 13. Restart your system by following the instructions in “Restarting the System” page 120. TSQ 8000 Evo Hardware Manual Thermo Scientific...
Page 185: Repeller Plate
Replacing Components of the Ion Source Repeller Plate  To replace the repeller plate: Note See the TSQ 8000 Evo Spare Parts Guide for information about ordering this component. 1. Shut down your system by following the steps in “Shutting Down the TSQ 8000 Evo System”...
Page 186 Figure 145. Removing the Source-Repeller Thumbscrews Source-Repeller Thumbscrews 6. Remove the thumbscrew-repeller spacers from the thumbscrews. Figure 146. Removing the Thumbscrew-Repeller Spacers Thumbscrew-Repeller Spacers 7. Move the locking ring out of the way. TSQ 8000 Evo Hardware Manual Thermo Scientific...
Page 187 13. Reattach the source-repeller thumbscrews. 14. Reattach the manifold door and the four screws. 15. Reattach the top cover and tighten the screw. 16. Restart your system by following the instructions in “Restarting the System” page 120. Thermo Scientific TSQ 8000 Evo Hardware Manual...
Page 188: Lens Heater Block Grounding Strap
Lens Heater Block Grounding Strap  To replace the lens heater block grounding strap: Note See the TSQ 8000 Evo Spare Parts Guide for information about ordering this component. 1. Shut down your system by following the steps in “Shutting Down the TSQ 8000 Evo System”...
Page 189: Lens Plate And Springs
Lens Plate and Springs  To replace the lens plate and springs Note See the TSQ 8000 Evo Spare Parts Guide for information about ordering these components. 1. Shut down your system by following the steps in “Shutting Down the TSQ 8000 Evo System”...
Page 190 6. Reattach the lens 1, lens 2, and lens 3 wires from the source interface board using a flat-tipped screwdriver. 7. Once the components are correctly reattached, follow the instructions in “Replacing the Analyzer Tray in the TSQ 8000 Evo Instrument” page 118 to replace the tray in the TSQ instrument.
Page 191: Source To Ion Guide Spacer
Replacing Components of the Ion Source Source to Ion Guide Spacer To replace the source to ion guide spacer: Note See the TSQ 8000 Evo Spare Parts Guide for information about ordering this component. WARNING - INSTRUMENT DAMAGE Thermo Fisher Scientific strongly recommends that only trained Thermo Fisher Scientific Field Service Engineers remove and service this component.
Page 192 5. Use a T20 Torxhead screwdriver to remove the two screws on the back of source block. Figure 153. Disconnecting the Source Block to the Analyzer Tray Screws Note Some of the pieces may detach as you loosen the screws. Do not let them fall. TSQ 8000 Evo Hardware Manual Thermo Scientific...
Page 193 Figure 154. Removing the Ion Source from the Analyzer Tray Source Interface Board Source Block Wires 7. Remove and replace the source to ion guide spacer. Figure 155. Replacing the Source to Ion Guide Spacer Source to Ion Guide Spacer Thermo Scientific TSQ 8000 Evo Hardware Manual...
Page 194 IMPORTANT When assembling the source and optics block, take extra care to ensure the blocks are centered properly and that the ion source cartridge provided with the instrument can easily slide in and out of the assembly. TSQ 8000 Evo Hardware Manual Thermo Scientific...
Page 195 11. Reconnect the Q1 entrance lens, Q1 exit lens, Q3 entrance lens, and Q3 exit lens to the source interface board using a flat-tipped screwdriver. 12. Once the components are correctly reattached, follow the instructions in “Replacing the Analyzer Tray in the TSQ 8000 Evo Instrument” page 118 to replace the tray in the TSQ instrument.
Page 196: Ion Source Cartridge
If the components of your ion source cartridge get damaged, you can use the illustration below to visually locate a component and then follow the process to replace it. Note See the TSQ 8000 Evo Spare Parts Guide for information about ordering this component.
Page 197 After you reattach the knob, press the Evacuate button to remove any air inside the vacuum interlock. Thermo Scientific TSQ 8000 Evo Hardware Manual...
Page 198 3. Grasp the handle of the source exchange tool in one hand and use your other hand to pull the metal barrel out and away from the handle so that tool is fully extended. 4. Attach the source exchange tool to the front of the instrument. TSQ 8000 Evo Hardware Manual Thermo Scientific...
Page 199 Figure 162. Inserting the Ion Volume Tool b. Twist and push the stainless steel barrel to the right until it clicks into place under the screw at the top of the slot. Figure 163. Twisting the Tool Into Place Thermo Scientific TSQ 8000 Evo Hardware Manual...
Page 200 6. Twist, then loosen the top part of the vacuum interlock handle to allow the entire handle to swing up and down. This handle controls the interior ball valve, which seals the vacuum chamber. TSQ 8000 Evo Hardware Manual Thermo Scientific...
Page 201 LED will flash on and off. CAUTION INSTRUMENT DAMAGE: Make sure the vacuum interlock handle is all the way up. Otherwise if you insert the tool with the handle down, you can damage the instrument. Thermo Scientific TSQ 8000 Evo Hardware Manual...
Page 202 11. Pull the tool toward you and down the left side of the metal track on the barrel. As you keep pulling it toward you, more and more of the barrel will be exposed. You may TSQ 8000 Evo Hardware Manual Thermo Scientific...
Page 203 12. Once you reach the end of the track (when the back line at the end of the barrel is uncovered by the black handle), twist the handle to the left to lock it into place. Figure 168. Locking the Tool in Place Note: Tool Rotated Left Thermo Scientific TSQ 8000 Evo Hardware Manual...
Page 204 16. Remove the tool from the instrument. TSQ 8000 Evo Hardware Manual Thermo Scientific...
Page 205 Advanced Troubleshooting Replacing Components of the Ion Source Figure 170. Removing the Tool from the Instrument Thermo Scientific TSQ 8000 Evo Hardware Manual...
Page 206 Figure 171. Exposing the Ion Source Cartridge Ion Source Cartridge 19. Invert the source exchange tool so that the barrel is pointed toward the floor. Figure 172. Inverting the Tool Ion Source Cartridge TSQ 8000 Evo Hardware Manual Thermo Scientific...
Page 207 Advanced Troubleshooting Replacing Components of the Ion Source 20. Slide the source holder, which is in the TSQ 8000 Evo Toolkit, onto the end of the ion source cartridge. The opening of the source holder is designed to accommodate the handles of the ion volume.
Page 208 26. Replace the ion source cartridge or any individual component. 27. Reassemble the ion source cartridge. 1. Place the ion volume-repeller insulator on the repeller and hold it in place with the repeller nut. Set it aside for now. TSQ 8000 Evo Hardware Manual Thermo Scientific...
Page 209 3. Align the long tooth of lens 3/RF lens with the notch on the bottom of the sleeve and drop the lens into the sleeve. Figure 177. Inserting Lens 3/RF Lens into the Source Sleeve Long Tooth on Lens 3/RF Lens Tooth Fits Here Thermo Scientific TSQ 8000 Evo Hardware Manual...
Page 210 5. With the longer teeth of lens 1 facing down toward lens 2, align the larger metal section of lens 1 with the sleeve window and let it fall into place. Figure 179. Inserting Lens 1 into the Source Sleeve Larger Metal Longer Teeth Section of Lens 1 Sleeve Window TSQ 8000 Evo Hardware Manual Thermo Scientific...
Page 211 Lens 1 Gap Note The ion volume handles are different sizes and will only fit into the sleeve one way. 7. Insert the ion volume repeller insulator onto the repeller. 8. Tighten the repeller nut. Thermo Scientific TSQ 8000 Evo Hardware Manual...
Page 212 Figure 181. Inserting the Repeller into the Source Sleeve Large Flat End of Repeller 10. Slide the repeller spring onto the repeller. Figure 182. Inserting the Repeller Spring into the Sleeve Repeller Spring TSQ 8000 Evo Hardware Manual Thermo Scientific...
Page 213: Reinserting The Ion Source Cartridge
IMPORTANT If you try to attach the ion source cartridge to the tool by inverting it, the components will likely fall, so make sure you are working over a table. Otherwise, you may have to stop and clean the components again. Thermo Scientific TSQ 8000 Evo Hardware Manual...
Page 214 Using too much force when inserting the ion source cartridge into the barrel can cause damage. TSQ 8000 Evo Hardware Manual Thermo Scientific...
Page 215 Figure 186. Removing the Source Holder Tip When the source exchange tool is inverted, the source should stay attached. If this does not happen, the source will not insert correctly into the instrument. Thermo Scientific TSQ 8000 Evo Hardware Manual...
Page 216 9. Insert the barrel end of the ion cartridge tool into the vacuum interlock and twist it to the right to lock it into position. Be sure the black handle remains in the locked position. Figure 187. Evacuating the Instrument Evacuate Button TSQ 8000 Evo Hardware Manual Thermo Scientific...
Page 217 IMPORTANT Make sure you take the correct track on the tool or the ion volume will disassemble inside the instrument. If that happens, the tool will get stuck and you will have to shut down, vent the TSQ 8000 Evo instrument, and manually remove the source cartridge through the top of the instrument.
Page 218 14. Twist the handle of the source exchange tool to the right and pull it back toward you and down the right side of the barrel’s metal track until the line at the end of the track appears. Figure 189. Pulling the Tool Down the Right Track TSQ 8000 Evo Hardware Manual Thermo Scientific...
Page 219 19. For optimal performance, wait at least 30 minutes for the ion source to heat up to the same temperature as the inside of the instrument. Otherwise, the masses or intensities may drift during operation Thermo Scientific TSQ 8000 Evo Hardware Manual...
Page 220: Replacing Components Of The Source Exchange Tool
If the components of your source exchange tool get worn or damaged, you can use the illustration below to visually locate a component and then follow the process to replace it. Note See the TSQ 8000 Evo Spare Parts Guide for information about ordering this component.
Page 221 Set Screw Endcap 6. Slide the handle off the rest of the tool. Set it aside. 7. Remove the interior shaft from the barrel. Figure 194. Removing the Interior Shaft Interior Shaft Barrel Thermo Scientific TSQ 8000 Evo Hardware Manual...
Page 222 Replace the seal, if necessary. 11. Insert the flared end of the seal into the end of the barrel. Figure 196. Inserting the Seal Flared End of Seal Bushing Barrel TSQ 8000 Evo Hardware Manual Thermo Scientific...
Page 223 20. Tighten the set screw. Note The purpose of the set screw is to keep the components together. Don’t overtighten it or the handle will be hard to slide up and down the barrel. Thermo Scientific TSQ 8000 Evo Hardware Manual...
Page 224: Replacing Components Of The Vacuum Interlock
If the components of your vacuum interlock get damaged, you can use the illustration below to visually locate a component and then follow the process to replace it. Note See the TSQ 8000 Evo Spare Parts Guide for information about ordering these components.
Page 225 Be sure to catch them and set them aside. Replace the spring and safety interlock, if necessary. Figure 201. Removing the Vacuum Interlock Knob Screws Spring and safety interlock are behind this screw Thermo Scientific TSQ 8000 Evo Hardware Manual...
Page 226 6. Pinch together the two springs on the left side the vacuum interlock shield and remove it. Figure 203. Removing the Vacuum Interlock Shield Vacuum Springs Interlock Handle Lower the Vacuum Interlock Handle TSQ 8000 Evo Hardware Manual Thermo Scientific...
Page 227 8. Use a T20 Torxhead screwdriver to remove the four screws found in the four corners of the manifold door. 9. Use a flathead screwdriver to disconnect the foreline hose at the 90° hose connector. Thermo Scientific TSQ 8000 Evo Hardware Manual...
Page 228 Figure 205. Removing the Clamp Foreline Hose Black Pillow Block Screws 11. Remove the three screws holding the metal valve body to the front manifold plate. Figure 206. Removing the Vacuum Interlock Handle Front Manifold Plate Screws TSQ 8000 Evo Hardware Manual Thermo Scientific...
Page 229 16. Remove the inner ball seal from the metal valve body. Replace the inner ball seal, if necessary. Tip It may be easier to remove the sealing ball if you push on it from the front, but be careful not to scratch the ball. Thermo Scientific TSQ 8000 Evo Hardware Manual...
Page 230 Sealing Ball Outer Ball Seal 19. Pry the thin metal clip out of the groove. It holds all of the other components inside the metal valve body. Figure 210. Replacing the Metal Clip Clip TSQ 8000 Evo Hardware Manual Thermo Scientific...
Page 231 21. Pull the valve axle out of the side of the metal valve body. Replace the valve axle, if necessary. 22. Remove the axle seal from the metal valve body. Replace the axle seal on the valve axle if necessary. Figure 212. Replacing the Axle Seal Axle Seal Thermo Scientific TSQ 8000 Evo Hardware Manual...
Page 232 Inner Ball Seal Valve Axle 24. Reinsert the axle bearing into the metal valve body. 25. Press and twist the thin metal clip into the top groove. Figure 214. Reinserting the Clip Clip TSQ 8000 Evo Hardware Manual Thermo Scientific...
Page 233 28. Insert the inner ball seal into the metal valve body. 29. Reattach the small spring and safety interlock to the metal valve body. Figure 216. Reattaching the Spring and Safety Interlock to the Metal Valve Body Safety Interlock Spring Thermo Scientific TSQ 8000 Evo Hardware Manual...
Page 234 Figure 217. Reattaching the Metal Valve Body from the Front Manifold Plate Vacuum Interlock Handle Shaft Valve Axle Screws Pillow Block 31. Slide the black pillow block over and onto the end of the valve axle. TSQ 8000 Evo Hardware Manual Thermo Scientific...
Page 235 Confirm the ball is fully opened and closed as the handle is moved up and down. Thermo Scientific TSQ 8000 Evo Hardware Manual...
Page 236 34. Reattach the manifold door and the four screws. Figure 220. Reattaching the Manifold Door Screws 35. Hold the spring and safety interlock in place as you attach the vacuum interlock shield and screws. 36. Reattach the vacuum interlock knob. TSQ 8000 Evo Hardware Manual Thermo Scientific...
Page 237 37. Reconnect the vacuum interlock cable from the connector. Figure 221. Reconnecting the Vacuum Interlock Cable Vacuum Interlock Cable Connector 38. Restart your system by following the instructions in “Restarting the System” page 120. Thermo Scientific TSQ 8000 Evo Hardware Manual...
Page 238: Replacing Components Of The Manifold
If the components of your manifold get damaged, you can use the illustration below to visually locate a component and then follow the process to replace it. Note See the TSQ 8000 Evo Spare Parts Guide for information about ordering these components.
Page 239: Manifold Door Hinge
Manifold Door Hinge  To replace the manifold door hinge: Note See the TSQ 8000 Evo Spare Parts Guide for information about ordering this component. 1. Shut down your system by following the steps in “Shutting Down the TSQ 8000 Evo System”...
Page 240 Replacing Components of the Manifold 4. The lens driver board is the first board standing on end in the center of the instrument. Figure 224. Locating the Lens Driver Board Lens Driver Board Bracket TSQ 8000 Evo Hardware Manual Thermo Scientific...
Page 241 7. Pinch together the two springs on the left side the vacuum interlock shield to free the hinge from the vacuum interlock shield. Figure 226. Freeing the Hinge from the Vacuum Interlock Shield Springs Thermo Scientific TSQ 8000 Evo Hardware Manual...
Page 242 8. Look through the left side of the instrument and use a T20 Torxhead screwdriver to remove the three screws connecting the hinge to the chassis. Figure 227. Replacing the Manifold Door Hinge Screws TSQ 8000 Evo Hardware Manual Thermo Scientific...
Page 243 11. Align the connector on the bottom of the lens driver board with the connectors on the distribution board beneath it. It will click into place when its in the right position. Figure 228. Reinstalling the Lens Driver Board Connector Thermo Scientific TSQ 8000 Evo Hardware Manual...
Page 244 Figure 229. Replacing the Lens Driver Board Lens Driver Board Screw 13. Replace the left hand front panel and tighten the two screws. 14. Restart your system by following the instructions in “Restarting the System” page 120. TSQ 8000 Evo Hardware Manual Thermo Scientific...
Page 245: Front Manifold Plate
Front Manifold Plate  To replace the front manifold plate: Note See the TSQ 8000 Evo Spare Parts Guide for information about ordering this component. 1. Shut down your system by following the steps in “Shutting Down the TSQ 8000 Evo System”...
Page 246 5. Lift the vacuum interlock shield off the instrument. The notch at the bottom of the track will go around the handle. Be sure to straighten the ball valve handle prior to removing the VPI shield. TSQ 8000 Evo Hardware Manual Thermo Scientific...
Page 247 6. Use a T20 Torxhead screwdriver to remove the four screws found in the four corners of the manifold door. 7. Use a flat head screwdriver to remove the VPI pump tube. Figure 233. Detaching the Manifold Door VPI Pump Tube Screws Thermo Scientific TSQ 8000 Evo Hardware Manual...
Page 248 9. Remove the three screws holding the metal block to the front manifold plate. Figure 235. Removing the Vacuum Interlock Handle Front Manifold Plate Note: Tube attached Screws 10. Set the vacuum interlock and all of its components aside. TSQ 8000 Evo Hardware Manual Thermo Scientific...
Page 249 13. Twist and remove the tray alignment pins that hold the magnet yoke to the back of the manifold door. The magnet yoke will pull free of the door, releasing the alignment collar. Figure 238. Removing the Tray Alignment Pins and Bracket Magnet Yoke Tray Alignment Pins Thermo Scientific TSQ 8000 Evo Hardware Manual...
Page 250 Figure 240. Reattaching the Front Plate O-Ring Manifold O-ring 16. Reattach the magnet yoke, alignment collar, and tray alignment pins. Figure 241. Re the Tray Alignment Pins and Bracket Magnet Yoke Tray Alignment Pins TSQ 8000 Evo Hardware Manual Thermo Scientific...
Page 251 Figure 242. Reattaching the Vent Valve Knob and O-Ring Vent Valve O-ring Vent Valve Knob 18. Reattach the three screws and metal block to the front manifold plate. Figure 243. Reattaching the Metal Block Note: Tube attached Screws Thermo Scientific TSQ 8000 Evo Hardware Manual...
Page 252 19. Reattach the two screws and black clamp to the front manifold plate Figure 244. Reattaching the Clamp Clamp Screws 20. Pinch the springs together and reattach the vacuum interlock shield to the hinge. Figure 245. Removing the Vacuum Interlock Shield Ball Valve Springs Handle TSQ 8000 Evo Hardware Manual Thermo Scientific...
Page 253 Figure 246. Reattaching the Vacuum Interlock Shield Screws Vacuum Interlock Shield 22. Reconnect the vacuum interlock cable and tubing Figure 247. Reattaching the Vacuum Interlock Cable and Vacuum Interlock Knob Vacuum Interlock Knob Vacuum Interlock Cable Connector Thermo Scientific TSQ 8000 Evo Hardware Manual...
Page 254 Advanced Troubleshooting Replacing Components of the Manifold 23. Reattach the vacuum interlock knob. 24. Restart your system by following the instructions in “Restarting the System” page 120. TSQ 8000 Evo Hardware Manual Thermo Scientific...
Page 255: Back Manifold Plate
Back Manifold Plate  To replace the back manifold plate: Note See the TSQ 8000 Evo Spare Parts Guide for information about ordering this component. 1. Shut down your system by following the steps in “Shutting Down the TSQ 8000 Evo System”...
Page 256 6. Remove the analyzer tray from the instrument by following the instructions in “Removing the Analyzer Tray from the TSQ 8000 Evo Instrument” page 109. 7. Disconnect the power cable from the left side of the TSQ 8000 Evo instrument. Figure 249. Disconnecting the Power Cables Power Cable Connector 8.
Page 257 14. Reattach the two screws holding the power supply to the instrument. 15. Reconnect the power cables on the left hand sub panel of the TSQ 8000 Evo instrument. 16. Replace the analyzer tray into the instrument by following the instructions in “Replacing...
Page 258: Magnets
Note For information about replacing the tray alignment pin on the back manifold plate, Back Manifold Plate. 1. Shut down your system by following the steps in “Shutting Down the TSQ 8000 Evo System” page 107. You do not have to remove the ion source cartridge or the column.
Page 259 Manifold O-ring Magnet Yoke Tray Alignment Pins Source Magnets 4. Close the manifold door and reattach the four screws. 5. Restart your system by following the instructions in “Restarting the System” page 120. Thermo Scientific TSQ 8000 Evo Hardware Manual...
Page 260: Vent Valve Knob And O-Ring
Vent Valve Knob and O-Ring  To replace the vent valve knob and o-ring Note See the TSQ 8000 Evo Spare Parts Guide for information about ordering these components. 1. Shut down your system by following the steps in “Shutting Down the TSQ 8000 Evo System”...
Page 261: Delivery Tubes
Replacing Components of the Manifold Delivery Tubes  To replace the delivery tubes Note See the TSQ 8000 Evo Spare Parts Guide for information about ordering this component. 1. Shut down your system by following the steps in “Shutting Down the TSQ 8000 Evo System”...
Page 262 4. Open the manifold door and replace the delivery tubes. Figure 255. Replacing the Delivery Tube Delivery Tubes 5. Close the manifold door and reattach the four screws. 6. Restart your system by following the instructions in “Restarting the System” page 120. TSQ 8000 Evo Hardware Manual Thermo Scientific...
Page 263: Replacing Components Of The Electron Multiplier
If the components of your electron multiplier get damaged, you can use the illustration below to visually locate a component and then follow the process to replace it. Note See the TSQ 8000 Evo Spare Parts Guide for information about ordering this component.
Page 264: Electron Multiplier Plate
Electron Multiplier Plate  To replace the electron multiplier plate: Note See the TSQ 8000 Evo Spare Parts Guide for information about ordering this component. 1. Shut down your system by following the steps in “Shutting Down the TSQ 8000 Evo System”...
Page 265 CAUTION - ELECTRICAL HAZARD Avoid dropping screws between chassis and side cover or board. If you drop a screw, find it before powering the instrument on again. Figure 259. Removing the Electrometer Board Screws Electron Multiplier Plate Thermo Scientific TSQ 8000 Evo Hardware Manual...
Page 266 O-ring Screws 7. Use a T20 Torxhead screwdriver to remove the four screws at each corner of the electron multiplier plate. Figure 261. Disconnecting the Electron Multiplier Plate Electron Multiplier Plate Screws TSQ 8000 Evo Hardware Manual Thermo Scientific...
Page 267 13. Put the electron multiplier plate back into place on the manifold and reattach the four screws. Reattach the electrometer board and the four screws. 14. Reattach the electrometer shield and the two screws Thermo Scientific TSQ 8000 Evo Hardware Manual...
Page 268 CAUTION INSTRUMENT DAMAGE: Do not mix up the cables or you will damage the power supply. 16. Reattach the top cover panel and tighten the screw. 17. Restart your system by following the instructions in “Restarting the System” page 120. TSQ 8000 Evo Hardware Manual Thermo Scientific...
Page 269: Large Feedthroughs
Large Feedthroughs  To replace the large feedthroughs, o-rings, and screws Note See the TSQ 8000 Evo Spare Parts Guide for information about ordering these components. 1. Shut down your system by following the steps in “Shutting Down the TSQ 8000 Evo System”...
Page 270 8. Use a T20 Torxhead screwdriver to reattach the four screws at each corner of the electron multiplier plate 9. Reconnect the large feedthrough cables. 10. Reattach the top cover panel and tighten the screw. 11. Restart your system by following the instructions in “Restarting the System” page 120. TSQ 8000 Evo Hardware Manual Thermo Scientific...
Page 271: Anode Feedthrough
Anode Feedthrough  To replace the anode feedthrough, o-ring, four screws, and a standoff: Note See the TSQ 8000 Evo Spare Parts Guide for information about ordering this component. 1. Shut down your system by following the steps in “Shutting Down the TSQ 8000 Evo System”...
Page 272 Figure 267. Removing the Electrometer Board Screws 6. Remove the electrometer board to reveal the anode feedthrough. Figure 268. Removing the Anode Feedthrough, O-ring, Standoff and Screws Anode Feedthrough and O-ring Standoff Screws TSQ 8000 Evo Hardware Manual Thermo Scientific...
Page 273: 12. Reconnect The Electrometer Board Cable And Large Feedthrough Cables
11. Reattach the electrometer shield and the four screws. 12. Reconnect the electrometer board cable and large feedthrough cables. 13. Restart your system by following the instructions in “Restarting the System” page 120. Thermo Scientific TSQ 8000 Evo Hardware Manual...
Page 274: Reinstalling The Tsq 8000 Evo System Software
Reinstalling the TSQ 8000 Evo System Software Reinstalling the TSQ 8000 Evo System Software Your TSQ 8000 Evo system has software on the instrument, as well as on the computer that was shipped with it. This section describes how to upgrade both of them.
Page 275: Upgrading Software On The Computer
Foundation and Xcalibur. If the CD contains later versions, follow the steps in the installation help document on the CD to update your software. To use Thermo Foundation 3.0 SP2 and Xcalibur 3.0 on Thermo Scientific GC-MS systems, you must have Xcalibur 3.0 Core Components for GC-MS installed on your computer.
Page 276: System Requirements
Advanced Troubleshooting Reinstalling the TSQ 8000 Evo System Software System Requirements The following system requirements apply to the Xcalibur 3.0and Foundation 3.0 SP2 core components. Layered applications may have different, higher requirements. Please refer to the applicable documentation and ensure that your PC meets the requirements before proceeding.
Page 277: Installing The Software Set
Note Check the latest Xcalibur Core Components for GC-MS CD for the most recent version of these installation instructions. To view the installation help document, select Browse CD and open the TSQ 8000 Evo Installation Help pdf. 1. Insert the Xcalibur 3.0 Core Components for GC-MS CD into the CD/DVD-ROM drive of your computer.
Page 278 Advanced Troubleshooting Reinstalling the TSQ 8000 Evo System Software layered applications. Click Run to run the .NET installation program. The .NET Framework installation will proceed through a series of windows that require you input. You must accept the Microsoft End User License Agreement (EULA) in order to install the .NET Framework.
Page 279 Advanced Troubleshooting Reinstalling the TSQ 8000 Evo System Software Note The Xcalibur 3.0 Core Components for GC-MS disc also includes the validation certificate for the Xcalibur core, the release notes for Foundation and Xcalibur and folders containing the manuals for these products. This content can be explored from the Xcalibur 3.0 Setup window using the Browse CD and Validation Certificate buttons.
Page 280: Replacing The Covers Of The Tsq 8000 Evo Instrument
If the covers of your instrument get damaged, you can use the illustration below to visually locate a component and then follow the process to replace it. Figure 271. Replaceable Covers of the TSQ 8000 Evo Instrument Top Cover Panel and Screws...
Page 281: Top Cover Panel
Top Cover Panel  To replace the top cover panel of the TSQ 8000 Evo instrument Note See the TSQ 8000 Evo Spare Parts Guide for information about ordering this component. 1. Shut down your system by following the steps in “Shutting Down the TSQ 8000 Evo...
Page 282: Left Hand Front Panel And Left Hand Sub Panel
Left Hand Front Panel and Left Hand Sub Panel  To replace the left hand front panel and the left hand sub panel of the TSQ 8000 Evo instrument Note See the TSQ 8000 Evo Spare Parts Guide for information about ordering this component.
Page 283 Advanced Troubleshooting Replacing the Covers of the TSQ 8000 Evo Instrument Figure 274. Finding the Inputs and Screws on the Left Hand Sub Panel Screw System Mech Pump Reagent Gas Connectors Connection Optional Mech Pump Connection AC Input Connector Collision Gas...
Page 284: Right Side Panel
Right Side Panel  To replace the right side panel of the TSQ 8000 Evo instrument Note See the TSQ 8000 Evo Spare Parts Guide for information about ordering this component. 1. Shut down your system by following the steps in “Shutting Down the TSQ 8000 Evo...
Page 285: Top Manifold Cover
Top Manifold Cover  To replace the top manifold cover Note See the TSQ 8000 Evo Spare Parts Guide for information about ordering this component. 1. Shut down your system by following the steps in “Shutting Down the TSQ 8000 Evo System”...
Page 286: Replacing The Chassis Feet
4. Remove the small and large glass covers in the manifold. 5. Carefully tip the TSQ 8000 Evo instrument and rest it on its left side. 6. Use a T20 Torxhead screwdriver to remove the screws holding any damaged feet to the bottom of the instrument.
Page 287 Advanced Troubleshooting Replacing the Covers of the TSQ 8000 Evo Instrument 11. Replace the analyzer tray into the instrument by following the instructions in “Replacing the Analyzer Tray in the TSQ 8000 Evo Instrument” page 118. 12. Restart your system by following the instructions in “Restarting the System”...
Page 288: Replacing Components Of The Front Door
Replacing Components of the Front Door Replacing Components of the Front Door If the front door of your TSQ 8000 Evo instrument gets damaged, you can use the illustration below to visually locate a replaceable component and then follow the process to replace it.
Page 289: Front Door Hinges And Supports
 To replace the hinges and supports that connect the front door to the chassis Note See the TSQ 8000 Evo Spare Parts Guide for information about ordering this component. 1. Shut down your system by following the steps in “Shutting Down the TSQ 8000 Evo...
Page 290 Note Replace one hinge at a time to prevent the door from falling. 7. Reattach the left hand front and top cover panels and tighten the screws. 8. Restart your system by following the instructions in “Restarting the System” page 120. TSQ 8000 Evo Hardware Manual Thermo Scientific...
Page 291: Front Door Latch
4. Slide the top cover panel off the instrument. 5. Open the front door of the GC and disconnect the column and transfer line nut. 6. Move the TSQ 8000 Evo instrument away from the GC so you can access the transfer line on the right side.
Page 292: Restarting The System
11. Reattach the right side and top cover panels and tighten the screws. 12. Reattach the GC to the transfer line. 13. Restart your system by following the instructions in “Restarting the System” page 120. TSQ 8000 Evo Hardware Manual Thermo Scientific...
Page 293: Replacing The Boards In The Tsq 8000 Evo Instrument
Replacing the Boards in the TSQ 8000 Evo Instrument Replacing the Boards in the TSQ 8000 Evo Instrument If the boards in your TSQ 8000 Evo instrument get damaged, you can use the illustration below to visually locate a board and then follow the process to replace it.
Page 294: Front And Rear Rf Boards And Front And Rear Rod Driver Boards
To replace the front and rear radio frequency (RF) boards and front and rear rod drive boards. Note See the TSQ 8000 Evo Spare Parts Guide for information about ordering an RF board. This board must be replaced by a Field Service Engineer, so when you place an order for a new board, schedule the Field Service Engineer as well.
Page 295 Advanced Troubleshooting Replacing the Boards in the TSQ 8000 Evo Instrument Figure 286. Locating the RF Boards and Brackets Rear RF Front RF Board Board Brackets 4. To remove the front RF board, use your fingers to pry the brackets of the board away from the chassis and toward the left side of the instrument.
Page 296 Advanced Troubleshooting Replacing the Boards in the TSQ 8000 Evo Instrument Figure 287. Removing the RF Board from the Instrument 6. Use a T10 Torxhead screwdriver to remove the three screws at each corner of the rod driver board. Be careful not to drop the parts under the metal cover.
Page 297 Advanced Troubleshooting Replacing the Boards in the TSQ 8000 Evo Instrument 7. Use a 2.5 mm nut driver to remove the standoffs on the rod driver board. Figure 288. Disconnecting the Rod Driver Board from the RF Board Screws Standoffs Rod Driver Board 8.
Page 298 Advanced Troubleshooting Replacing the Boards in the TSQ 8000 Evo Instrument Figure 290. Disconnecting the Rod Driver Board 7-Pin Connector 7-Pin Connector Note Be careful not to bend the connector on the rod driver board on the pins on the RF board.
Page 299 Advanced Troubleshooting Replacing the Boards in the TSQ 8000 Evo Instrument 13. Insert a new RF board by aligning the connectors on the bottom of the board with the connectors on the distribution board beneath it. It will drop into the slot when it is in the right position.
Page 300: Rf Board/Rod Driver Board Kits
2. Slide the top cover panel toward the back of the instrument and lift it off. Note The TSQ 8000 Evo system contains a front and a rear RF board/rod driver kit. The steps are the same to replace each kit, except for the location.
Page 301 Advanced Troubleshooting Replacing the Boards in the TSQ 8000 Evo Instrument Figure 293. Locating the RF Boards and Brackets Rear RF Front RF Board Board Brackets 4. Use your fingers to pry the bracket of the board away from the chassis and toward the left side of the instrument.
Page 302 Advanced Troubleshooting Replacing the Boards in the TSQ 8000 Evo Instrument 6. Insert a new RF board/rod driver board kit by aligning the connectors on the bottom of the board with the connectors on the distribution board beneath it. It will drop into the slot when it is in the right position.
Page 303: 4- Pin Feedthrough
4- Pin Feedthrough  To replace the 4-pin feedthrough: Note See the TSQ 8000 Evo Spare Parts Guide for information about ordering these components. 1. Shut down your system by following the steps in “Shutting Down the TSQ 8000 Evo System”...
Page 304 6. Remove the RF board attached to the feedthrough you wish to change. The front RF board is the second board standing on end toward the center of the TSQ 8000 Evo instrument. The rear RF board is the second board standing on end toward the center of the instrument.
Page 305 10. Set the glass cover on a surface where it will not be scratched or contaminated. Protect the glass and any other manifold components from dust accumulation. Wear cleanroom gloves when touching the glass. See the TSQ 8000 Evo Spare Parts Guide for information about ordering cleanroom gloves.
Page 306 Advanced Troubleshooting Replacing the Boards in the TSQ 8000 Evo Instrument Figure 300. Removing the Large Glass Manifold Covers Large Glass Manifold Cover CAUTION - ELECTRICAL HAZARD Avoid dropping screws between chassis and side cover or board. If you drop a screw, find it before powering the instrument on again.
Page 307 Advanced Troubleshooting Replacing the Boards in the TSQ 8000 Evo Instrument 12. Remove and replace the 4-pin feedthrough. You can also remove and replace the o-ring, if necessary. 13. Reattach the 4-pin feedthrough to the chassis. 14. Replace the large glass manifold cover.
Page 308: Lens Driver Board
Lens Driver Board  To replace the lens driver board Note See the TSQ 8000 Evo Spare Parts Guide for information about ordering this component. 1. Shut down your system by following the steps in “Shutting Down the TSQ 8000 Evo System”...
Page 309 Advanced Troubleshooting Replacing the Boards in the TSQ 8000 Evo Instrument 5. The lens driver board is the first board standing on end in the center of the instrument. Figure 303. Locating the Lens Driver Board Lens Driver Bracket Board CAUTION - INSTRUMENT DAMAGE Do not touch the components of the boards.
Page 310 Advanced Troubleshooting Replacing the Boards in the TSQ 8000 Evo Instrument 6. Look through the left side of the instrument and use a T20 Torxhead screwdriver to loosen the screw holding the board to the chassis. Tip The bracket has a white diagram describing the location of this screw. It is approximately two inches from the top of the board directly under the white label.
Page 311 Advanced Troubleshooting Replacing the Boards in the TSQ 8000 Evo Instrument 9. Insert a new lens driver board by aligning the connector on the bottom of the board with the connectors on the distribution board beneath it. It will drop into the slot when it is in the right position.
Page 312: 20-Pin Feedthrough
Replacing the Boards in the TSQ 8000 Evo Instrument 20-Pin Feedthrough To replace the 20-pin feedthrough: Note See the TSQ 8000 Evo Spare Parts Guide for information about ordering this component. 1. Shut down your system by following the steps in “Shutting Down the TSQ 8000 Evo...
Page 313 Advanced Troubleshooting Replacing the Boards in the TSQ 8000 Evo Instrument Figure 307. Locating the Lens Driver Board Lens Driver Bracket Board 6. Look through the left side of the instrument and use a T20 Torxhead screwdriver to loosen the screw holding the board to the chassis. Loosening the screw will separate the board from the instrument.
Page 314 8. Remove the top manifold cover (glass) out of the top of the instrument and set it aside. 9. Open the front door of the TSQ 8000 Evo instrument. 10. Use a T20 Torxhead screwdriver to remove the four screws around the manifold door.
Page 315 Advanced Troubleshooting Replacing the Boards in the TSQ 8000 Evo Instrument Figure 309. Opening the Manifold Door Screws 11. Open the manifold door and slide the filament board and wires off the pins on the source interface board. Figure 310. Disconnecting the Filament Wires...
Page 316 Advanced Troubleshooting Replacing the Boards in the TSQ 8000 Evo Instrument Figure 311. Removing the Heat Shield Filament Board Source Interface Left and Wires Board Screw Heat Shield Note Keep all manifold parts you remove covered on a clean work surface so they will not accumulate dust.
Page 317 Advanced Troubleshooting Replacing the Boards in the TSQ 8000 Evo Instrument 13. Look through the top of the instrument and use the heat shield to pry the source interface board off of the 20-pin feedthrough. Figure 312. Detaching the Source Interface Board From the 20-Pin Feedthrough...
Page 318 Advanced Troubleshooting Replacing the Boards in the TSQ 8000 Evo Instrument 15. Remove and replace the 20-pin feedthrough. If necessary, replace the o-ring and make sure it is properly aligned and free of dust. Figure 314. Replacing the 20-Pin Feedthrough O-ring 16.
Page 319 Advanced Troubleshooting Replacing the Boards in the TSQ 8000 Evo Instrument 18. Slide the heat shield into its slot and reattach the screw holding it in place. 19. Reattach the filament board to the source interface board. 20. Close the manifold door and reattach the four screws.
Page 320: Pc Communication Board, Controller Interface Board, And Support
 To replace the PC communication board, controller interface board, or support bracket Note See the TSQ 8000 Evo Spare Parts Guide for information about ordering these components. 1. Shut down your system by following the steps in “Shutting Down the TSQ 8000 Evo System”...
Page 321 5. Locate the PC communication board, which is attached to the controller interface board. Note Although the PC communication board is attached to the controller interface board, they are sold separately. See the TSQ 8000 Evo Spare Parts Guide for ordering information.
Page 322 Advanced Troubleshooting Replacing the Boards in the TSQ 8000 Evo Instrument 8. Remove the controller interface board and PC communication board from the instrument. Figure 319. Removing the Controller Interface Board Support Bracket Controller Interface Board Support Bracket Screws PC Communication Board 9.
Page 323 Advanced Troubleshooting Replacing the Boards in the TSQ 8000 Evo Instrument Figure 320. Removing the Support Bracket Screws Screws Thermo Scientific TSQ 8000 Evo Hardware Manual...
Page 324 Advanced Troubleshooting Replacing the Boards in the TSQ 8000 Evo Instrument 11. Incrementally, and very carefully, disconnect the PC communication board from the controller interface board by separating the two connectors. Inspect the pins to be certain they are not bent.
Page 325 Advanced Troubleshooting Replacing the Boards in the TSQ 8000 Evo Instrument 15. Insert the new controller interface board by aligning the two connectors on the bottom of the board to the connectors on the distribution board beneath it. It will drop into the slot when it is in the right position.
Page 326: Distribution Board
Advanced Troubleshooting Replacing the Boards in the TSQ 8000 Evo Instrument Distribution Board The distribution board lies on the bottom of the TSQ 8000 Evo instrument chassis.  To replace the distribution board Note See the TSQ 8000 Evo Spare Parts Guide for information about ordering this component.
Page 327 5. Locate the PC communication board, which is attached to the controller interface board. Note Although the PC communication board is attached to the controller interface board, they are sold separately. See the TSQ 8000 Evo Spare Parts Guide for ordering information.
Page 328 Advanced Troubleshooting Replacing the Boards in the TSQ 8000 Evo Instrument 8. Remove the controller interface board and PC communication board from the instrument. Figure 325. Removing the Controller Interface Board Support Bracket Controller Interface Board Support Bracket Screws PC Communication Board 9.
Page 329 Advanced Troubleshooting Replacing the Boards in the TSQ 8000 Evo Instrument Figure 326. Removing the Chassis Cooling Fan and Pan Plenum Fan Plenum Left Side Air Deflector Screws Front Screws 12. Disconnect the fan from the distribution board on the bottom of the instrument.
Page 330 Advanced Troubleshooting Replacing the Boards in the TSQ 8000 Evo Instrument 13. The lens driver board is the first board standing on end in the center of the instrument. Figure 327. Locating the Lens Driver Board Lens Driver Bracket Board...
Page 331 Advanced Troubleshooting Replacing the Boards in the TSQ 8000 Evo Instrument 14. Look through the left side of the instrument and use a T20 Torxhead screwdriver to loosen the screw holding the board to the chassis. Tip The bracket has a white diagram describing the location of this screw. It is approximately two inches from the top of the board directly under the white label.
Page 332 Advanced Troubleshooting Replacing the Boards in the TSQ 8000 Evo Instrument the TSQ 8000 Evo instrument. Use a T20 Torxhead screwdriver to remove the screws holding the board and brackets to the chassis. Figure 329. Locating the RF Boards and Brackets...
Page 333 Replacing the Boards in the TSQ 8000 Evo Instrument Figure 330. Removing the Front RF Board from the TSQ 8000 Evo Instrument 20. To remove the rear RF board, use your fingers to pry the brackets of the board away from the chassis and toward the left side of the instrument.
Page 334 Advanced Troubleshooting Replacing the Boards in the TSQ 8000 Evo Instrument 24. Use a T20 Torxhead screwdriver to remove the two screws holding the power module to the instrument. Figure 332. Removing the Power Module Screws Screws 25. Pull the power supply out of the top of the instrument.
Page 335 Advanced Troubleshooting Replacing the Boards in the TSQ 8000 Evo Instrument Figure 333. Removing the Dynode/Multiplier Power Supply Dynode/Multiplier Power Supply Bottom Screw 27. Disconnect the 1/16 in. collision gas tubing from the bulkhead compression fitting located on the left hand sub panel.
Page 336 Advanced Troubleshooting Replacing the Boards in the TSQ 8000 Evo Instrument Figure 334. Disconnecting the Cable to the Bulkhead Fitting Collision Gas Module Bulkhead Tubing Fitting 28. Disconnect the collision gas module cable from the distribution board. 29. If you are using CI, follow the instructions in the...
Page 337 Advanced Troubleshooting Replacing the Boards in the TSQ 8000 Evo Instrument Figure 335. Disconnecting the Distribution Board Distribution Board Cables 31. Disconnect all the cables from the distribution board. Also remove the cable that enters the chassis from the back panel.
Page 338 Advanced Troubleshooting Replacing the Boards in the TSQ 8000 Evo Instrument 43. Reconnect the large feedthrough cables on the electron multiplier plate. 44. Reattach the RF boards by aligning the connectors on the bottom of the board with the connectors on the distribution board beneath it. The boards will drop into their slots when they are in the right position.
Page 339 Advanced Troubleshooting Replacing the Boards in the TSQ 8000 Evo Instrument connectors on the distribution board beneath it. It will click into place when its in the right position. Figure 337. Reinstalling the Controller Interface Board Connectors Figure 338. Reinstalling the Controller Interface Board...
Page 340: Source Interface Board And Heat Shield
Source Interface Board and Heat Shield  To replace the source interface board and heat shield Note See the TSQ 8000 Evo Spare Parts Guide for information about ordering these components. 1. Shut down your system by following the steps in “Shutting Down the TSQ 8000 Evo...
Page 341 Figure 340. Reconnecting the Source Interface Board Wires 8. Once the components are correctly attached to the analyzer tray, follow the instructions “Replacing the Analyzer Tray in the TSQ 8000 Evo Instrument” page 118 replace the tray in the TSQ instrument.
Page 342: Electrometer Board Cable
Electrometer Board Cable  To replace the electrometer board (15-pin male/female RS-232) cable Note See the TSQ 8000 Evo Spare Parts Guide for information about ordering this component. 1. Shut down your system by following the steps in “Shutting Down the TSQ 8000 Evo System”...
Page 343 Advanced Troubleshooting Replacing the Boards in the TSQ 8000 Evo Instrument 5. Use a T20 Torxhead screwdriver to remove the two screws holding the power module to the instrument. Figure 342. Removing the Power Module Screws Screws 6. Pull the power supply out of the top of the instrument.
Page 344: Electrometer Board And Shield
Electrometer Board and Shield  To replace the electrometer board and shield Note See the TSQ 8000 Evo Spare Parts Guide for information about ordering these components. 1. Shut down your system by following the steps in “Shutting Down the TSQ 8000 Evo System”...
Page 345 Advanced Troubleshooting Replacing the Boards in the TSQ 8000 Evo Instrument 6. Remove the four screws holding the electrometer board in place Figure 344. Replacing the Electrometer Board Screws 7. Remove and replace the electrometer board if necessary. 8. Reattach the screws that hold the electrometer board in place.
Page 346: Replacing The Power Supplies
Replacing the Power Supplies Replacing the Power Supplies If the power supplies in your TSQ 8000 Evo instrument get damaged, you can use the illustration below to visually locate a power supply and then follow the process to replace it.
Page 347: Power Module
Replacing the Power Supplies Power Module  To replace the power module Note See the TSQ 8000 Evo Spare Parts Guide for information about ordering this component. 1. Shut down your system by following the steps in “Shutting Down the TSQ 8000 Evo System”...
Page 348 Advanced Troubleshooting Replacing the Power Supplies Figure 346. Locating the TSQ 8000 Evo System Power Cables System Mech Pump Connection Optional Mech Pump Connection AC Input Connector TSQ 8000 Evo Hardware Manual Thermo Scientific...
Page 349 It will drop into the connector when it is in the right position. 8. Make sure the new module is flush against the top of the chassis and the screw holes line 9. Reattach the two screws holding the power module to the instrument. Thermo Scientific TSQ 8000 Evo Hardware Manual...
Page 350 11. Reattach the top cover panel and tighten the screw holding it in place. Reattach the hydrogen safety screws if you are using hydrogen. 12. Restart your system by following the instructions in “Restarting the System” page 120. TSQ 8000 Evo Hardware Manual Thermo Scientific...
Page 351: Dynode And Multiplier Power Supply
Dynode and Multiplier Power Supply  To replace the dynode and multiplier power supply Note See the TSQ 8000 Evo Spare Parts Guide for information about ordering this component. 1. Shut down your system by following the steps in “Shutting Down the TSQ 8000 Evo System”...
Page 352 5. Make sure the electrometer board cable is not in the way when you remove the power module. 6. Grasp the power supply system and lift it out of the instrument. It fits snugly, so you may have to gently shake it as you lift it out. TSQ 8000 Evo Hardware Manual Thermo Scientific...
Page 353 7. Disconnect the large feedthrough cables labeled Dynode and Electron Multiplier. Figure 349. Disconnecting the Electron Multiplier Cables Electrometer Board Cable Dynode Electron Multiplier Electron Multiplier Plate 8. Disconnect the cables from the clips attached to the chassis. Thermo Scientific TSQ 8000 Evo Hardware Manual...
Page 354 Note A new dynode/multiplier power supply may have a right angle bracket attached to the top of the supply. Remove this bracket before placing the supply into the TSQ 8000 Evo instrument. TSQ 8000 Evo Hardware Manual Thermo Scientific...
Page 355 14. Connect the large feedthrough cables. 15. Replace the main power supply. 16. Reattach the top cover panel and tighten the screw. 17. Restart your system by following the instructions in “Restarting the System” page 120. Thermo Scientific TSQ 8000 Evo Hardware Manual...
Page 356: Replacing The Calibration Gas Components
Replacing the Calibration Gas Components Replacing the Calibration Gas Components If the calibration gas components of your TSQ 8000 Evo instrument get damaged, you can use the illustration below to visually locate a component and then follow the process to replace it.
Page 357: Calibration Gas Module
 To replace the EI calibration gas module Note See the TSQ 8000 Evo Spare Parts Guide for information about ordering this component. 1. Shut down your system by following the steps in “Shutting Down the TSQ 8000 Evo System”...
Page 358 Support Bracket 6. Disconnect the Ethernet cable from the PC communication board. Figure 355. Disconnecting the Ethernet Cable from the PC Communication Board Controller Interface Board PC Communication Ethernet Board Cable Connector Connectors TSQ 8000 Evo Hardware Manual Thermo Scientific...
Page 359 The rear RF board is the third board standing on end toward the center of the TSQ 8000 Evo instrument. Use a T20 Torxhead screwdriver to remove the screw holding the board and bracket to the chassis.
Page 360 12. Lift the lens driver board out of the instrument. Be careful as space is limited. CAUTION - INSTRUMENT DAMAGE Limit handling of the boards as much as possible. Do not touch any board components. Hold the board by the sheet metal bracket only. TSQ 8000 Evo Hardware Manual Thermo Scientific...
Page 361 17. Use a T20 Torxhead screwdriver to remove the two screws holding the module to the interior front panel. The tubing will come off with it. 18. Remove the calibration gas module from the front panel and attach a new one. Thermo Scientific TSQ 8000 Evo Hardware Manual...
Page 362 24. Gently push the RF board toward the instrument, carefully aligning the board over the feedthrough pins, until it stops. 25. Reattach the screw holding the RF board to the bracket. Note This screw is required for good ground contact. TSQ 8000 Evo Hardware Manual Thermo Scientific...
Page 363 27. Push the board down into the connectors. 28. Look through the left side of the instrument and use a T20 Torxhead screwdriver to reattach the screw holding the lens driver board in place on the chassis. Thermo Scientific TSQ 8000 Evo Hardware Manual...
Page 364 33. Reattach the top cover and left hand front panels and tighten the screws. If you are using hydrogen, reattach the hydrogen safety screws. 34. Restart your system by following the instructions in “Restarting the System” page 120. TSQ 8000 Evo Hardware Manual Thermo Scientific...
Page 365: Calibrant Reservoir Kit
To replace the calibrant reservoir kit, which consists of the calibrant reservoir and its cover Note See the TSQ 8000 Evo Spare Parts Guide for information about ordering these components. If you just need to refill the calibrant reservoir and not replace it, see Refilling the Calibrant Reservoir.
Page 366 8. Close the front door of the instrument. 9. If you are using hydrogen as a carrier gas, attach the hydrogen safety screws and restart your GC by following the instructions in “Restarting the System” page 120. TSQ 8000 Evo Hardware Manual Thermo Scientific...
Page 367: Gas Mixing Chamber
Gas Mixing Chamber  To replace the gas mixing chamber Note See the TSQ 8000 Evo Spare Parts Guide for information about ordering this component. 1. Shut down your system by following the steps in “Shutting Down the TSQ 8000 Evo System”...
Page 368: Transfer Line
107. 2. Open the front door of the GC and disconnect the column and transfer line nut. 3. Move the TSQ 8000 Evo instrument away from the GC so you can access the transfer line on the right side. WARNING BURN HAZARD: The transfer line may be hot, so be careful.
Page 369 9. Remove the screw on the lower right side that is holding the analyzer tray to the manifold. Figure 367. Disconnecting the Analyzer Tray from the Instrument Gas Mixing Chamber Calibration and Reagent Gas Tubes Right Screw Thermo Scientific TSQ 8000 Evo Hardware Manual...
Page 370 13. Use a T20 screwdriver to remove the two screws holding the transfer line to the chassis. 14. Pull the transfer line straight away from the instrument so you do not damage it. Make sure the o-ring is removed as well. Replace the o-ring, if necessary. TSQ 8000 Evo Hardware Manual Thermo Scientific...
Page 371 21. Slide the right side panel back onto the instrument and reattach the screws. 22. Reposition the TSQ 8000 Evo instrument closer to the GC. 23. Reinsert the column to the proper length and tighten the transfer line nut. See “Replacing...
Page 372: Replacing The Collision Gas Components
Replacing the Collision Gas Components Replacing the Collision Gas Components The collision gas components you can order and replace in the TSQ 8000 Evo system are the collision gas module, the collision gas tubing, the tee that connects the collision gas tubing to the foreline adapter, and the foreline adapter itself.
Page 373 Advanced Troubleshooting Replacing the Collision Gas Components 7. Move the TSQ 8000 Evo instrument away from the GC so you can access the transfer line on the right side. WARNING BURN HAZARD: The transfer line may be hot, so be careful.
Page 374 11. To remove the rear RF board, use your fingers to pry the brackets of the board away from the chassis and toward the left side of the instrument. 12. Lift the board out of the TSQ 8000 Evo instrument. TSQ 8000 Evo Hardware Manual...
Page 375 Controller Interface Board Support Bracket 14. Remove the controller interface board and PC communication board from the instrument. The boards are attached together. 15. Disconnect the Ethernet cable from the PC communication board. Thermo Scientific TSQ 8000 Evo Hardware Manual...
Page 376 17. If you need to replace the tee, unscrew it from the foreline adapter and replace it. You may also replace the foreline adapter if necessary. 18. Disconnect the collision gas tubing from the module. The tubing is secured to the module using a compression fitting. TSQ 8000 Evo Hardware Manual Thermo Scientific...
Page 377 If you are replacing the tubing to the collision cell, disconnect the collision gas tubing from the collision cell and from the compression fitting on the manifold. Figure 377. Disconnecting the Tubing from the Collision Cell Collision Gas Tubing Thermo Scientific TSQ 8000 Evo Hardware Manual...
Page 378 Figure 379. Disconnecting the Cable to the Bulkhead Fitting Collision Gas Module Bulkhead Tubing Fitting 24. Use a T20 Torxhead screwdriver to remove the two screws on the collision gas module. 25. Remove the collision gas module and replace if necessary. TSQ 8000 Evo Hardware Manual Thermo Scientific...
Page 379 35. Replace the rear RF board. 36. Replace the top, left hand front, and right side panels and secure with screws. 37. Move the TSQ 8000 Evo next to the GC. 38. Restart your system by following the instructions in “Restarting the System”...
Page 380: Replacing Fans And Filters
Replacing Fans and Filters Replacing Fans and Filters To efficiently cool the TSQ 8000 Evo instrument while it is being used, air must be allowed to flow in through the front of the instrument and out the back. The instrument is equipped with a fan that keeps the air flowing and filters that minimize the amount of dust that enters the system.
Page 381 Advanced Troubleshooting Replacing Fans and Filters Fan Plenum Left Rear Wire Air Deflector Mesh Filter Turbo Cooling Thermo Scientific TSQ 8000 Evo Hardware Manual...
Page 382: Front Wire Mesh Filter
Front Wire Mesh Filter  To replace the front wire mesh filter Note If needed, you can order an additional dust filter. See the TSQ 8000 Evo Spare Parts Guide for ordering information. 1. Shut down your system by following the steps in “Shutting Down the TSQ 8000 Evo...
Page 383: Left Rear Wire Mesh Filter
Left Rear Wire Mesh Filter  To replace the left rear wire mesh filter Note See the TSQ 8000 Evo Spare Parts Guide for ordering information. 1. Shut down your system by following the steps in “Shutting Down the TSQ 8000 Evo System”...
Page 384: Chassis Cooling Fan And Fan Plenum
Chassis Cooling Fan and Fan Plenum  To replace the chassis cooling fan and fan plenum Note See the TSQ 8000 Evo Spare Parts Guide for information about ordering this component. 1. Shut down your system by following the steps in “Shutting Down the TSQ 8000 Evo...
Page 385 Tip The bracket has a white diagram describing the location of this screw. It is approximately two inches from the top of the board directly under the white label. Thermo Scientific TSQ 8000 Evo Hardware Manual...
Page 386 8. Lift the lens driver board out of the instrument. Be careful as space is limited. CAUTION - INSTRUMENT DAMAGE Limit handling of the boards as much as possible. Do not touch any board components. Hold the board by the sheet metal bracket only. TSQ 8000 Evo Hardware Manual Thermo Scientific...
Page 387 Screws Front Screws 9. Remove the six screws holding the fan plenum to the chassis. Two are on the left side of the instrument, and four are attached to the interior front panel. Thermo Scientific TSQ 8000 Evo Hardware Manual...
Page 388 19. Replace the lens driver board by aligning the connector on the bottom of the board with the connectors on the distribution board beneath it. It will drop into the slot when it is in the right position. 20. Push the lens driver board down into the connector. TSQ 8000 Evo Hardware Manual Thermo Scientific...
Page 389 22. Reattach the left hand front panel and tighten the four screws holding it in place. 23. Reattach the top cover panel and tighten the screw holding it in place. 24. Restart your system by following the instructions in “Restarting the System” page 120. Thermo Scientific TSQ 8000 Evo Hardware Manual...
Page 390: Air Deflector
Replacing Fans and Filters Air Deflector  To replace the air deflector Note See the TSQ 8000 Evo Spare Parts Guide for ordering information. 1. Shut down your system by following the steps in “Shutting Down the TSQ 8000 Evo System”...
Page 391 8. Reattach the two rivets holding the air deflector to the chassis cooling fan. 9. Reattach the four screws securing the left hand front panel to the chassis. 10. Restart your system by following the instructions in “Restarting the System” page 120. Thermo Scientific TSQ 8000 Evo Hardware Manual...
Page 392: Turbo Cooling Fan And Turbo Cooling Fan Filter
 To replace the turbo cooling fan and turbo cooling fan filter Note See the TSQ 8000 Evo Spare Parts Guide for ordering information. 1. Shut down your system by following the steps in “Shutting Down the TSQ 8000 Evo System”...
Page 393 7. Lift the left hand front panel off the instrument. 8. The lens driver board is the first board standing on end in the center of the instrument. Figure 393. Locating the Lens Driver Board Lens Driver Bracket Board Thermo Scientific TSQ 8000 Evo Hardware Manual...
Page 394 11. Lift the lens driver board out of the instrument. Be careful as space is limited. CAUTION - INSTRUMENT DAMAGE Limit handling of the boards as much as possible. Do not touch any board components. Hold the board by the sheet metal bracket only. TSQ 8000 Evo Hardware Manual Thermo Scientific...
Page 395 Cable Front Screws 12. Remove the six screws holding the fan plenum to the chassis. Two are on the left side of the instrument, and four are attached to the interior front panel. Thermo Scientific TSQ 8000 Evo Hardware Manual...
Page 396 17. If you need to replace the turbo cooling fan filter, use a T10 Torxhead screwdriver to remove the four screws holding the turbo cooling fan filter to the interior front panel. 18. Remove and replace the turbo cooling fan filter. TSQ 8000 Evo Hardware Manual Thermo Scientific...
Page 397 Advanced Troubleshooting Replacing Fans and Filters Figure 397. Replacing the Turbo Cooling Fan Filter Screws 19. Reattach the two screws holding the turbo cooling fan filter to the interior front panel. Thermo Scientific TSQ 8000 Evo Hardware Manual...
Page 398 24. Replace the lens driver board by aligning the connector on the bottom of the board with the connectors on the distribution board beneath it. It will drop into the slot when it is in the right position. 25. Push the lens driver board down into the connector. TSQ 8000 Evo Hardware Manual Thermo Scientific...
Page 399 28. Replace the left hand front panel and reattach the four screws. 29. Replace the top cover panel and reattach the top cover panel screw. 30. Reattach the GC. 31. Restart your system by following the instructions in “Restarting the System” page 120. Thermo Scientific TSQ 8000 Evo Hardware Manual...
Page 400: Replacing The Turbomolecular Pump
Panel Screws 4. Make sure the electrometer board cable is not in the way when you remove the power module. 5. Disconnect the power cables from the side of the TSQ 8000 Evo instrument. TSQ 8000 Evo Hardware Manual Thermo Scientific...
Page 401 Advanced Troubleshooting Replacing the Turbomolecular Pump Figure 401. Locating the TSQ 8000 Evo System Power Cables System Mech Pump Connection Optional Mech Pump Connection AC Input Connector Thermo Scientific TSQ 8000 Evo Hardware Manual...
Page 402 6. Use a T20 Torxhead screwdriver to remove the two screws holding the power supply system to the top of the back panel. Figure 402. Removing the Power Module Screws Screws 7. Grasp the power supply system and lift it out of the instrument. It fits snugly, so you may have to gently shake it as you lift it out.
Page 403 11. Use a 13 mm wrench to loosen the four clamps at the top of the turbomolecular pump. 12. Remove the two clamps that hold the turbomolecular pump to the manifold on the transfer line side. Thermo Scientific TSQ 8000 Evo Hardware Manual...
Page 404 15. Insert a new turbomolecular pump into the chassis. Note There is a centering ring with an o-ring seal that must be correctly placed between the pump and the vacuum manifold. TSQ 8000 Evo Hardware Manual Thermo Scientific...
Page 405 24. Replace the right side panel and tighten the five screws. 25. Replace the top cover panel and tighten the screw. 26. Reattach the GC. 27. Restart your system by following the instructions in “Restarting the System” page 120. Thermo Scientific TSQ 8000 Evo Hardware Manual...
Page 406: Convectron Gauge And Foreline Adapter With Hose
 To replace a convectron gauge and foreline adapter with hose Note See the TSQ 8000 Evo Spare Parts Guide for ordering information. 1. Shut down your system by following the steps in “Shutting Down the TSQ 8000 Evo System”...
Page 407 Figure 407. Removing the Right Side Panel Screws Right Side Panel Screws 7. Disconnect the vacuum hose from the adapter on the foreline pump. 8. Remove the rough pump clamp on the turbomolecular pump and the adapter. Thermo Scientific TSQ 8000 Evo Hardware Manual...
Page 408 13. Reattach the right side panel and the screws holding it in place. 14. Replace the top cover panel and tighten the screw. 15. Reattach the GC. 16. Restart your system by following the instructions in “Restarting the System” page 120. TSQ 8000 Evo Hardware Manual Thermo Scientific...
Page 409: Chapter 4 Upgrade Equipment
Upgrade Equipment This chapter describes how to install the upgrade equipment that is available for the TSQ 8000 Evo mass spectrometer. See the TSQ 8000 Evo Spare Parts Manual for information about ordering the equipment in this chapter. Contents •...
Page 410: Dust Filter
Dust Filter Dust Filter An optional dust filter is available for the TSQ 8000 Evo system. It helps prevent dust from accumulating on the electrical components and damaging your system. If you have a particularly dusty environment, the dust filter will help your instrument operate at a cooler temperature for a longer period of time.
Page 411: Ci Reagent Gas Flow Module
The CI reagent gas flow module controls the flow of CI reagent gas into the ion source and is located at the back left of the TSQ 8000 Evo instrument. The module uses electronic pressure control to precisely set the flow of reagent gas. The flow is programmed using the instrument control software, which allows you to accurately reproduce flows.
Page 412 Figure 411. Locating Components on the Left Hand Sub Panel Left Hand System Mech Pump Reagent Gas (A & B) Connectors Screw Sub Panel Connection Power Switch Optional Mech Pump Connection AC Input Connector Screw Screw TSQ 8000 Evo Hardware Manual Thermo Scientific...
Page 413 10. Remove the three screws holding the left hand sub panel to the chassis and pull the panel away to expose the screws that hold the CI reagent gas flow module to the chassis. Thermo Scientific TSQ 8000 Evo Hardware Manual...
Page 414 Screws 12. Disconnect the Ethernet cable from the PC communication board. 13. Remove the controller interface board and PC communication board from the instrument. The two boards are connected. Do not separate them. TSQ 8000 Evo Hardware Manual Thermo Scientific...
Page 415 16. Use a T20 Torxhead screwdriver to detach the two screws holding the CI reagent gas flow module to the chassis Figure 415. Installing the CI Reagent Gas Flow Module Screws CI Reagent Gas Flow Module CI Output Foreline Gas Connector Tube Thermo Scientific TSQ 8000 Evo Hardware Manual...
Page 416 Figure 416. Attaching a CI Tube to the Transfer Line CI Tube Transfer Line Tubing Connector 22. Look through the top of the instrument and confirm that the CI tube is attached to the mixing chamber and manifold wall. TSQ 8000 Evo Hardware Manual Thermo Scientific...
Page 417 25. Reattach the two screws holding the power module to the instrument. 26. Reattach the controller interface board, the PC communication board, and the support bracket. Thermo Scientific TSQ 8000 Evo Hardware Manual...
Page 418 35. Restart your system by following the instructions in “Restarting the System” page 120. Note Purge air fro the CI reagent gas supply tubing overnight before using your TSQ 8000 instrument to acquire data. TSQ 8000 Evo Hardware Manual Thermo Scientific...
Page 419: Ci Ion Volume
Repeller Spring Ion Cartridge Sleeve Lens 1 Lens 3/RF Lens Repeller Repeller Figure 420. Ion Volumes Available for the TSQ 8000 Evo Mass Spectrometer EI Ion Volume CI Ion Volume EI/CI Ion Volume Thermo Scientific TSQ 8000 Evo Hardware Manual...
Page 420: Ei/Ci Ion Volume
Repeller Spring Ion Cartridge Sleeve Lens 1 Lens 3/RF Lens Repeller Repeller Figure 422. Ion Volumes Available for the TSQ 8000 Evo Mass Spectrometer CI Ion Volume EI Ion Volume EI/CI Ion Volume TSQ 8000 Evo Hardware Manual Thermo Scientific...
Page 421: Ion Gauge And Tube Shield
2. Slide the top cover panel toward the back of the instrument and lift it off. 3. Move the GC away from the TSQ 8000 Evo instrument. 4. Use a T20 Torxhead screwdriver to remove the five screws on the right side panel.
Page 422 9. Attach the 14-pin cable to the distribution board and ion gauge board. Figure 425. Connecting the Ion Gauge Cable to the Distribution Board Ion Gauge Cable Connector 10. Remove the plug on the bottom of the manifold. TSQ 8000 Evo Hardware Manual Thermo Scientific...
Page 423 13. Replace the right side panel and attach the screws holding it in place. 14. Reattach the top cover panel and tighten the screw holding the top cover panel in place. 15. Restart your system by following the instructions in “Restarting the System” page 120. Thermo Scientific TSQ 8000 Evo Hardware Manual...
Page 424: Probe Controller
Then replace the ion source into the instrument and allow it time to thermally equilibrate. See the ISQ and TSQ 8000 Direct Probe System User Guide for more details. TSQ 8000 Evo Hardware Manual Thermo Scientific...
Page 425 CI ion volume installing, back manifold plate CI reagent gas flow module installing, installing, boards cleaning replacing delicate components, drying delicate components, 20-pin feedthrough kit, drying durable components, 4-pin feedthrough, Thermo Scientific TSQ 8000 Evo Hardware Manual...
Page 426 System or Optional Mech Pump, gas mixing chamber, contaminants, removing, transfer line, contamination issues, investigating, chassis cooling fan, control board covers replacing, convectron gauge and foreline adapter with hose chassis feet, illustration, left side panel, TSQ 8000 Evo Hardware Manual Thermo Scientific...
Page 427 (complete) checking oil, preserving, connecting, replacing, purging gas from the oil, electron multiplier components troubleshooting, illustration, when to replace, Thermo Scientific TSQ 8000 Evo Hardware Manual...
Page 428 Evacuate, ion guide (illustration), Heaters, ion guide-quadrupole stabilizer, replacing, Power, ion source block Vacuum, illustration, replacing, ion source cartridge assembling, maintenance cleaning, cleaning the filters, illustration (exploded view), cleaning the ion source cartridge, TSQ 8000 Evo Hardware Manual Thermo Scientific...
Page 429 Power Supply Check diagnostics, about, right side panel, power supply issues, investigating, top cover panel, powering off the TSQ 8000, top manifold cover, Thermo Scientific TSQ 8000 Evo Hardware Manual...
Page 430 RF shields and intake filters, replacing, 356–357, 364, Thermo Foundation, installing, RF/DC issues, investigating, thumbscrew-repeller spacers RF/DC System Check diagnostics, about, illustration, 155, 157, 160–161 right side panel replacing, TSQ 8000 Evo Hardware Manual Thermo Scientific...
Page 431 TSQ 8000 Evo venting the TSQ 8000 Evo, configuring, 4, 257, 322, 375, filters, foreline pump, lights on front panel, WEEE compliance model and serial number,...

Thermo Scientific TSQ 8000 Evo Hardware Manual

Preface

Chapter 1 Performing Routine Maintenance

Chapter 2 Troubleshooting

Chapter 3 Advanced Troubleshooting

Chapter 4 Upgrade Equipment

Quick Links

Troubleshooting

Related Manuals for Thermo Scientific TSQ 8000 Evo

Summary of Contents for Thermo Scientific TSQ 8000 Evo

Table of Contents