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1-54
Parameters
*
Indicates parameters available only on Rapidlab 1260 and Rapidlab 1265 systems.
†
Indicates parameters available only on Rapidlab 1245 and Rapidlab 1265 systems.
The sections that follow briefly describe the clinical significance of each of these
parameters.
Bicarbonate Ion
The majority of CO
which is the major buffer substance present in the body. Bicarbonate plays a central role in
maintaining the pH level in blood.
Bicarbonate levels are clinically significant in helping to determine the nonrespiratory,
renal (metabolic) component in acid-base blood disorders.
Two versions of bicarbonate exist:
•
Actual bicarbonate (HCO
values, based on the recommendations from the Clinical and Laboratory Standards
Institute (CLSI) as follows:
HCO
•
Standard bicarbonate (HCO
concentration if the blood is equilibrated to a pCO
described by VanSlyke and Cullin
HCO
where
A
and if sO
NOTE:
15 g/dL as a default value.
Base Excess
Base excess is an empirical expression that approximates the amount of acid or base
required to titrate 1 liter of blood to a normal pH of 7.40. Base excess is a clinically useful
way of assessing the metabolic portion of the acid-base balance.
02087462 Rev. V
Rapidlab 1200 Operator's Guide: System Overview and Intended Use
Results
BO
2
p50
is transported through the body as the bicarbonate ion (HCO
2
–
act = 0.0307 × pCO
3
−
=
+
std
24
5 .
0
9 .
3
×
×
0
2 .
tHB
( )
=
−
BE
B
is available, it is used in place of O
2
If ctHb is not available as an entered value or a measured value, the system uses
Description
oxygen binding capacity
oxygen tension at 50% saturation
–
act), which is determined directly from the pH and pCO
3
(pH(37)–6.105)
× 10
2
–
std), which is a determination of the plasma HCO
3
30
:
[
[
]
(
)
(
−
2
A
2
9 .
. 2
65
×
+
A
1000
(
( )
)
−
100
O
SAT
est
2
100
SAT(est).
2
9
of 40 mmHg
using the equation
2
]
)
+
×
. 0
31
tHB
9
–
),
3
2
–
3
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