Thermo Scientific Dionex UltiMate 3000 Series Operating Instructions Manual page 220

UltiMate 3000 Series:
NCS-3500RS and NCP-3200RS
Test
a) Pressure up the pump. This is the best way to identify a leaking connection.
b) Allow 5 minutes for the pump to stabilize. This is important as the pressure drops
faster during the first 5 minutes, because the seals and other components have to
adjust the pressure.
c) After the stabilization time, monitor the pressure drop.
d) Tighten the connection a little more tight. The pressure will suddenly increase a little.
e) Monitor if the pressure drops at the same rate as before. If the pressure drops
significantly slower, the connection was leaking.
8. In Chromeleon, reset the upper pressure limit to the value used before the leak test.
Tip: If leakage from a pump head is observed, check also the tubing connected to
the rear seal wash system. If the seal wash tubing is not connected properly or
if the tubing is crimped or kinked, the liquid may leak into the pump.
Page 212 Operating Instructions