Thermo Scientific Dionex UltiMate 3000 Series Operating Instructions Manual page 117

Nano/cap system. nano/cap pump
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In an UltiMate 3000 system, some components are made of PEEK. This polymer has
superb chemical resistance to most organic solvents.
However, it tends to swell when in contact with trichlormethane (CHCl
sulfoxide (DMSO), or tetrahydrofuran (THF). In addition, it is attacked by concentrated
acids, such as, sulfuric acid and nitric acid or a mixture of hexane, ethyl acetate, and
methanol. In both cases, capillaries may start leaking or they can burst. Swelling or attack
by concentrated acids is not a problem with brief flushing procedures. For more
information about the chemical resistance of PEEK, see the table in section 12.1
(→ page 247).
Before switching from buffer to organic solution, rinse the pump thoroughly with
deionized water.
When switching to another solvent, ensure that the new solvent is miscible with the one
contained in the pump. Otherwise, the pump can be damaged; for example, by
flocculation.
When replacing solvents, make sure that the solvents are miscible. Mix immiscible
solvents with an intermediate solvent (for example, isopropanol) to replace them step-by-
step.
After operation, rinse out buffers and solutions that form peroxides.
Important:
Important:
Operating Instructions
Neither recycle the solvent nor use methanol from aluminum
reservoirs. This may impair the performance of the seals.
Thermo Fisher Scientific déconseille de recycler les solvants ou
employer du méthanol stocké dans des réservoirs en aluminium.
Ceci peut affecter les performances des joints.
UltiMate 3000 Series:
NCS-3500RS and NCP-3200RS
), dimethyl
3
Page 109

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