Intellistart Fluidics Physical Layout - Waters SYNAPT G2 Operator's, Overview And Maintenance Manual

For nanoACQUITY UPLC, the valves and pumps that make up the
IntelliStart Fluidics system introduce dead volume, which causes
unacceptable peak broadening. For this reason, the nanoACQUITY UPLC is
plumbed directly to the NanoFlow sprayer using a suitably short piece of silica
tubing.
For reference flows for both the LockSpray and NanoLockSpray source, the
IntelliStart Fluidics system delivers reference solution from vial B or, for
extended operating hours, from a separate, external bottle of reference
solution.

IntelliStart Fluidics physical layout

The IntelliStart Fluidics system comprises the components shown in the
following figure.
System components and configuration
(Tubing connections omitted for clarity)
Access doors
Lock-spray pump
Sample pump
1-10 System Overview
Lock-spray selector valve
Tubing guides
A
B
C
Flow sensor
Sample selector valve
Grounded union
A
B
C
C
B
A
Wa ters
C
B
A
Diverter valve
Sample vials
(A, B, and C)