Dual-Mode Ionization Source; Matrix-Assisted Laser Desorption Ionization; Intellistart Fluidics System; Overview - Waters SYNAPT G2 Operator's, Overview And Maintenance Manual

Dual-mode ionization source

Atmospheric pressure photoionization (APPI) uses photons generated by a
discharge UV lamp (~10.2 eV) to produce sample ions from vaporized LC
eluent. Direct photoionization of the sample molecule occurs when the photon
energy exceeds the ionization potential of the sample molecule.
The optional dual-mode (APPI/APCI) ionization source incorporates an APPI
source enclosure used in conjunction with a standard APCI probe. You can
operate the source in APPI, APCI, or dual-mode, which switches rapidly
between ionization modes, facilitating high-throughput analyses.
The Waters SYNAPT G2 Dual-mode Ionization Source Operator's
See also:
Guide.

Matrix-assisted laser desorption ionization

The matrix-assisted laser desorption ionization (MALDI) interface enables
rapid, tool-free switching between API and MALDI modes. A motorized stage
moves the MALDI source into position.
The Waters MALDI SYNAPT G2 MS System Operator's Guide.
See also:

IntelliStart Fluidics system

Overview

The IntelliStart Fluidics system is built into the instrument; it controls how
sample is delivered to the source.
For standard flow applications, the system delivers sample directly to the
mass spectrometer source in one of three ways:
• From the LC column.
• From three integral vials.
The vials can also deliver sample through direct or combined
Tip:
infusion to enable optimization at analytical flow rates.
• From a wash reservoir that contains solvent for flushing the
instrument's solvent delivery system.
IntelliStart Fluidics system 1-9