Instrument sources ........................................................................................... 1-5
NanoLockSpray source .................................................................................... 1-7
Overview........................................................................................................... 1-9
System operation ........................................................................................... 1-11
Ion optics ........................................................................................................... 1-12
Analyzers ........................................................................................................... 1-13
Quadrupole..................................................................................................... 1-13
Triwave technology ........................................................................................ 1-14
TOF analyzer ................................................................................................. 1-15
Triwave device ............................................................................................... 1-17
TOF................................................................................................................. 1-17
Leak sensors ..................................................................................................... 1-18
Vacuum system ................................................................................................ 1-18
UPLC/MS/MS system ................................................................................ 2-3
Installing the vials ........................................................................................... 2-4
Purging the pump ............................................................................................ 2-5
xii
Table of Contents