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Xevo TQD IVD
Waters Xevo TQD IVD Manuals
Manuals and User Guides for Waters Xevo TQD IVD. We have
1
Waters Xevo TQD IVD manual available for free PDF download: Overview And Maintenance Manual
Waters Xevo TQD IVD Overview And Maintenance Manual (148 pages)
Brand:
Waters
| Category:
Laboratory Equipment
| Size: 3 MB
Table of Contents
Trademarks
3
Contacting Waters
3
Safety Considerations
4
Safety Hazard Symbol Notice
4
Considerations Specific to the Xevo TQD IVD
4
Electrical Power Safety Notice
7
Equipment Misuse Notice
7
Safety Advisories
7
Operating this Instrument
7
Applicable Symbols
8
Audience and Purpose
9
Compliance with Medical Device Regulations
9
Intended Use of the Xevo TQD IVD
9
Available UPLC Inlets
10
Calibrating
10
Canada Spectrum Management Emissions Notice
11
EMC Considerations
11
EC Authorized Representative
12
FCC Radiation Emissions Notice
12
Table of Contents
13
1 Specifications and Operating Modes
19
Uses and Compatibility
19
Intellistart Technology
19
Software and Data System
20
Instrument Console Software
20
Electrospray Ionization (ESI)
21
Intellistart Fluidics System
21
Functionality
21
System Operation
22
Ion Optics
22
MS Operating Modes
24
MS/MS Operating Modes
25
Product Ion Mode
26
Precursor Ion Mode
27
Multiple Reaction Monitoring Mode
27
PICS Mode
27
Radar
27
Constant Neutral-Loss Mode
28
Sample Inlet
29
Leak Sensors
29
Vacuum System
29
Rear Panel Connections
30
2 Preparing for Operation
31
Starting the Mass Spectrometer
31
Verifying the Mass Spectrometer's State of Readiness
32
Monitoring the Mass Spectrometer's Leds
32
Tuning and Calibration Information
33
Running the Mass Spectrometer at Different Flow Rates
33
Preparing the Intellistart Fluidics System
33
Installing the Reservoir Bottles
33
Purging the Infusion Pump
34
Rebooting the Mass Spectrometer's Software
34
Leaving the Mass Spectrometer Ready for Operation
35
Emergency Shutdown of the Mass Spectrometer
35
3 Installing and Removing the ESI Probe
37
Installing the ESI Probe
37
Required Material
37
Removing the ESI Probe
39
Required Material
39
4 Maintenance Procedures
41
Maintenance Schedule
41
Spare Parts
42
Troubleshooting with Connections INSIGHT
43
Safety and Handling
44
Preparing the Instrument for Operations on or Inside Its Source
44
Removing and Refitting the Source Enclosure
45
Removing the Source Enclosure from the Instrument
45
Fitting the Source Enclosure to the Instrument
46
Operating the Source Isolation Valve
47
Required Material
47
Removing O-Rings and Seals
49
Cleaning the Instrument Case
49
Emptying the Exhaust Trap Bottle
50
Required Material
50
Gas Ballasting the Roughing Pump
51
Gas Ballasting a Pump Fitted with a Screwdriver-Operated Gas Ballast Valve
52
Gas Ballasting a Pump Fitted with a Handle-Operated Gas Ballast Valve
53
Checking the Roughing Pump Oil Level
54
Adding Oil to the Roughing Pump
54
Required Materials
54
Replacing the Roughing Pump's Oil
55
Required Materials
55
Replacing the Roughing Pump's Oil Demister Element
57
Required Materials
57
Replacing the Turbomolecular Pump's Oil Reservoir
61
Required Materials
61
Cleaning the Source Components
63
Cleaning the Sampling Cone Assembly
64
Removing the Sampling Cone Assembly from the Source
64
Disassembling the Sampling Cone Assembly
65
Cleaning the Sample Cone and Cone Gas Nozzle
68
Assembling the Sampling Cone Assembly
69
Fitting the Sampling Cone Assembly to the Source
70
Cleaning the Extraction Cone
71
Removing the Ion Block Assembly from the Source Assembly
71
Removing the Extraction Cone from the Ion Block
72
Cleaning the Extraction Cone
74
Fitting the Extraction Cone to the Ion Block
75
Fitting the Ion Block Assembly to the Source Assembly
76
Cleaning the Ion Block Assembly
76
Disassembling the Source Ion Block Assembly
76
Cleaning the Ion Block Components
83
Assembling the Source Ion Block Assembly
84
Cleaning the Ion Guide Assembly
86
Removing the Ion Block Assembly and Ion Guide from the Source Assembly
86
Cleaning the Ion Guide Assembly
88
Removing the Differential Aperture from the Ion Guide
90
Fitting the Differential Aperture to the Ion Guide Assembly
91
Fitting the Ion Guide Assembly to the Source Assembly
92
Fitting the Ion Block Support to the Source
92
Replacing the ESI Probe Tip and Gasket
93
Removing the ESI Probe Tip and Gasket
93
Fitting the ESI Probe Tip and Gasket
95
Replacing the ESI Probe Sample Capillary
96
Removing the Existing Capillary
96
Installing the New Capillary
99
Replacing the Ion Block Source Heater
102
Required Materials
102
Replacing the Source Assembly Seals
105
Removing the Probe Adjuster Assembly Probe Seal and Source Enclosure Seals
106
Fitting the New Source Enclosure and Probe Adjuster Assembly Seals
107
Replacing the Air Filter
108
Required Material
108
Replacing the Instrument's Fuses
110
A Safety Advisories
111
Warning Symbols
111
Specific Warnings
112
Notices
114
Bottles Prohibited Symbol
114
Required Protection
114
Warnings that Apply to All Waters Instruments and Devices
115
Warnings that Address the Replacing of Fuses
118
Electrical and Handling Symbols
119
Electrical Symbols
119
Handling Symbols
121
B External Connections
123
External Wiring and Vacuum Connections
123
Connecting the Oil-Filled Roughing Pump
124
Connecting Electric Cables to the Oil-Filled Roughing Pump
127
Connecting the Edwards Oil-Free Roughing Pump
128
Required Materials
128
Connecting Electric Cables to the Edwards Oil-Free Roughing Pump
130
Connecting to the Nitrogen Gas Supply
131
Required Materials
131
Connecting to the Collision Cell Gas Supply
132
Required Materials
132
Connecting the Nitrogen Exhaust Line
132
Connecting the Liquid Waste Line
135
Required Material
135
Connecting the Workstation
137
Connecting Ethernet Cables
138
I/O Signal Connectors
138
Signal Connections
139
Connecting to the Power Supply
141
C Materials of Construction and Compliant Solvents
143
Items Exposed to Solvent
143
Solvents Used to Prepare Mobile Phases
144
D Plumbing the Intellistart Fluidics System
145
Preventing Contamination
145
The Selector Valve
145
Plumbing Schematic
146
Tubing and Connection Specifications
147
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