Ion Optics - Waters Xevo G2-XS QTof Overview And Maintenance Manual

Ion optics

The mass spectrometer's ion optics operate in the following sequence:
1. Samples from the LC or instrument's solvent delivery system are
introduced at atmospheric pressure into the ionization source.
2. The ions pass through the sample cone and into the vacuum system.
3. The ions pass through the StepWave™ ion guide to the quadrupole,
where they are filtered according to their mass-to-charge ratio.
4. The mass-separated ions pass into the XS Collision Cell, where they can
undergo collision-induced dissociation (CID).
5. The ions, focused by the transfer lenses, pass into the time-of-flight (Tof)
analyzer. A high voltage pulse orthogonally accelerates the ions up the
flight tube, where a reflectron reflects them back toward the detector.
Ions of different mass-to-charge ratios arrive at the detector at different
times. The difference in the arrival times provides the basis for a mass
spectrum.
6. The signal from the detector is amplified, digitized, and transmitted to
the software.
April 2, 2015, 715004496 Rev. B

Ion optics

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