Nanolockspray Source And Ionization Modes - Waters Xevo G2-XS QTof Overview And Maintenance Manual

1 Waters Xevo G2-XS QTof Overview

NanoLockSpray source and ionization modes

The NanoLockSpray source allows ESI in the flow rate range of
5 to 1,000 nL/min. For a given sample concentration, the ion currents for
similar experiments approximate those in normal flow rate electrospray.
However, because sample consumption is greatly reduced, the sensitivity
gains are significant when you use similar scan parameters.
Lock-mass correction with the NanoLockSpray source works as the LockSpray
source does in ESI mode.
The NanoLockSpray source enclosure consists of a sprayer — universal or
borosilicate glass capillary, (see below) — mounted on a ZSpray three-axis
manipulator.
A light within the source provides illumination for the spray, which you can
observe using the video camera mounted on the corner of the source housing,
(see page 74).
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