Maintaining The Ionsabre Ii Probe; Cleaning The Ionsabre Ii Probe Tip; Replacing The Ionsabre Ii Probe Sample Capillary - Waters Vion IMS QTof Overview And Maintenance Manual

27. Fit the ESI probe to the source enclosure (see
28. Use the nebulizer adjuster knob to fine tune the capillary length for your application (see
the instrument's online Help file).

5.17 Maintaining the IonSABRE II probe

Maintaining the IonSABRE II probe involves cleaning the probe tip or replacing the probe
capillary when required.
Note:
To maintain a tool-free APCI probe, see the Waters Tool-Free Probe Maintenance Guide
Supplement (715005492).

5.17.1 Cleaning the IonSABRE II probe tip

Clean the IonSABRE II probe tip when you detect buffer buildup on the probe tip or when the
signal intensity weakens. See the mass spectrometer's online Help for further details.
To clean the IonSABRE II probe tip:
1. Stop all liquid flow through the probe, and then start the API gas flow.
2. Set Desolvation Gas to 650 L/h.
3. Set IonSABRE II probe Temp to 650 °C.
4. Click Operate
5. Wait 10 minutes.
Rationale:
contamination from the probe tip.
6. Click Source Standby

5.17.2 Replacing the IonSABRE II probe sample capillary

Replace the stainless steel sample capillary in the IonSABRE II probe if it becomes blocked and
you cannot clear it, or if it becomes contaminated or damaged.
5.17.2.1 Removing the existing capillary
Required materials
• Chemical-resistant, powder-free gloves
• Combined 2.5-mm hex wrench and cone extraction tool
• 7-mm open-end wrench
.
The high IonSABRE II probe heater temperature removes any chemical
.
March 17, 2021, 715005046 Ver. 03
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Installing the ESI probe (Page 36)).