Waters Vion IMS QTof Overview And Maintenance Manual page 12

1.3 Fluidics system...............................................................................................................................23
1.3.1 Physical layout of the Fluidics system.................................................................................. 24
1.3.2 System operation.................................................................................................................. 25
1.4 Ion optics........................................................................................................................................ 25
1.5 Leak sensors.................................................................................................................................. 27
1.6 Vacuum system.............................................................................................................................. 27
2 Preparing the Mass Spectrometer for Operation....................................................29
2.1 Starting the mass spectrometer..................................................................................................... 29
2.1.1 Verifying the instrument's state of readiness........................................................................ 30
2.1.2 Automated setup...................................................................................................................31
2.1.3 Flow rates for the Vion IMS QTof system..............................................................................31
2.2 Preparing the Fluidics system........................................................................................................ 31
2.2.1 Installing the reservoir bottles............................................................................................... 32
2.2.2 Installing the low-volume vials.............................................................................................. 33
2.2.3 Purging the fluidics................................................................................................................33
2.3 Rebooting the mass spectrometer................................................................................................. 33
2.4 Leaving the mass spectrometer in Standby mode......................................................................... 34
2.5 Emergency shutdown.....................................................................................................................35
3 Configuring the LockSpray Source......................................................................... 36
3.1 Configuring the LockSpray source................................................................................................. 36
3.2 Configuring for ESI mode............................................................................................................... 36
3.2.1 Installing the ESI probe.........................................................................................................36
3.2.2 Removing the ESI probe.......................................................................................................40
3.3 Configuring for APCI mode............................................................................................................ 40
3.3.1 Installing the IonSABRE II probe.......................................................................................... 41
3.3.2 Removing the IonSABRE II probe........................................................................................ 43
4 Configuring the NanoLockSpray Source................................................................ 44
4.1 Overview of the NanoLockSpray source........................................................................................ 44
4.1.1 Sample sprayer.....................................................................................................................46
4.1.2 LockSpray sprayer................................................................................................................ 46
March 17, 2021, 715005046 Ver. 03
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