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Solvent leakage hazard
The source exhaust system is designed to be robust and leak-tight. Waters recommends that you
perform a hazard analysis, assuming a maximum leak into the laboratory atmosphere of 10% LC
eluate.
Warning:
To avoid exposure to toxic substances and biohazards from O-ring leaks in the source
exhaust system, observe these precautions:
• Replace the source O-rings at intervals not exceeding one year.
• Prevent chemical degradation of the source O-rings, which can withstand exposure only to
certain solvents, by determining whether any solvents you use are chemically compatible with
the composition of the O-rings.
Bottle placement prohibition
Warning:
To avoid injury from electrical shock or fire, and damage to the equipment, follow
these guidelines:
• Do not expose the workstation or ancillary equipment to dripping or splashing liquids.
• Do not place objects filled with liquid, such as solvent bottles, on top of the workstation or
ancillary equipment.
Spilled solvents hazard
Prohibited:
reservoir bottles directly atop an instrument or device or on its front ledge. Instead,
place the bottles in the bottle tray, which serves as secondary containment in the event
of spills.
Flammable solvents hazard
Warning:
a mass spectrometer's ion source, ensure that these conditions are met:
• Nitrogen flows continuously through the source.
• A gas-fail device is installed to interrupt the flow of LC solvent should the nitrogen
supply fail.
• The nitrogen supply pressure does not fall below 400 kPa (4 bar, 58 psi) during an
analysis requiring the use of flammable solvents.
To avoid equipment damage caused by spilled solvent, do not place
To prevent the ignition of flammable solvent vapors in the enclosed space of
March 17, 2021, 715005046 Ver. 03
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