Gambro Cobe Spectra Essentials Manual page 16

Preface
Warning: The following can cause fluid imbalances:
•
Administration of replacement fluids that are not at room
temperature
•
Use of improperly vented replacement fluid containers
•
Equipment malfunction
•
Improper line clamping or valve loading
•
During an RBCX procedure, use of an inadequately primed or
clotted RBC leukoreduction filter on the replacement line.
Refer to the filter manufacturer's guidelines to ensure the
filter meets replacement fluid flow rates.
Monitor all solutions and procedures for correct fluid balance.
Warning: The following can cause fluid imbalances:
•
Use of inadequately primed or clotted microaggregate filters
on the replacement line
•
Administration of replacement fluids that are not at room
temperature
•
Use of improperly vented replacement fluid containers
•
Equipment malfunction
•
Improper line clamping or valve loading
Monitor all solutions and procedures for correct fluid balance.
Warning: The risks and complications of using fresh frozen
plasma (FFP) in plasma exchange are the same as those
associated with the therapeutic administration of FFP as described
by the American Association of Blood Banks and the American
Red Cross. However, using large volumes of FFP can increase the
frequency and severity of these complications.
1-10
Warning: When using biologically-derived replacement fluids,
closely monitor the patient for reactions.
Warning: DO NOT unload the disposable tubing set if the donor
or patient is connected to the Spectra system, or the donor or
patient may receive anticoagulant and other unwanted fluids
through the access and return needles.
Warning: Opening the needle clamp and the saline line roller
clamp before taking a blood sample may result in an embolism. To
avoid a possible embolism, use the sampling bag to take a
sample. If you do not use the sampling bag, first prime the needle
with saline.
Warning: Failure to flush the tubing with saline may result in
blood clotting in the tubing, which may result in clot(s) returning to
the donor.
Warning: In most cases, TPE procedures will not significantly
alter the therapeutic effect of a patient's medications. It is
advisable, however, to obtain a detailed drug history before each
procedure. For those drugs potentially affected by TPE
procedures, the physician should either adjust the doses or give
the medications immediately after the procedure.
Warning: Repeated daily TPE procedures using plasma-poor
replacement fluids will increase the depletion of the patient's
coagulation factors.
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COBE Spectra™ Apheresis System • Essentials Guide