Agilent Technologies 7500 ICP-MS Operator's Manual page 497

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3 Click the Bias Correction check box to make mass bias correction.
N O T E
4 Click the Browse push button.
5 Select the standard data file to be used for calculating the mass bias correction,
Agilent 7500 ICP-MS ChemStation Operator's Manual
Performing an Isotope Ratio Analysis
The Bias Correction check box will be checked.
ICP-MS does not have the exact same sensitivity for all masses. Variations in mass
response (mass bias) occur in the interface, ion lenses, analyzer and detection
systems. Mass bias is more severe at low mass, where the percentage mass difference
between adjacent masses is higher. In general, however, mass bias is relatively
constant and easily corrected for by calculating the mass bias factor obtained from a
certified isotopic standard. It is recommended that the mass bias factor be calculated
using the same element that is to be measured.
The Select Data File dialog box appears.
Select Data File Dialog Box
using one of the following methods:
• Click a file name in the displayed list and click OK.
• Double-click a file name in the displayed list.
• Type the file name and click OK.
The dialog box will disappear and the selected standard data file will be indicated
next to the Browse push button.
14-5

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