Intended Use - Thermo Scientific Dionex UltiMate 3000 Series Operating Instructions Manual

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UltiMate 3000 Series:
TCC-3000SD and TCC-3000RS Column Compartments

1.3 Intended Use

For Research Use Only. Not for use in diagnostic procedures.
The device is designed to be operated only be qualified and authorized personnel. All users
must know the hazards presented by the device and the used substances.
The TCC is designed for laboratory research use in high-performance liquid
chromatography (HPLC) or ultra-high performance liquid chromatography (UHPLC)
applications. It is part of the UltiMate 3000 system, but can be used also with other HPLC
systems if adequate control inputs and outputs are available. A PC with USB port is
required. The TCC is controlled by the Chromeleon CHROMATOGRAPHY
MANAGEMENT SYSTEM. Being part of the UltiMate 3000 system, the TCC can also be
operated with other data systems, such as
Xcalibur™, Compass™/HyStar™, or Analyst
To do so, installation of the DCMSLink (Dionex Chromatography Mass Spectrometry
Link) software is required in addition to the installation of the data system.
Empower™
Installation of the Dionex Instrument Integration Software is required in addition to the
installation of the data system.
For more information, contact the Thermo Fisher Scientific sales organization for Dionex
HPLC Products.
Observe the following:
Note that the TCC may be operated only with accessories and spare parts recommended
by Thermo Fisher Scientific (→ page 115) and within its technical specifications
(→ page 113).
Use only standard solvents (HPLC grade or LC-MS grade: 0.2 µm filtered) and buffers
that are compatible with components in the flow path of the TCC. Note the special
properties of the solvents, such as the viscosity, boiling point, UV absorption (UV/VIS
detector), and refractive index (refractive index detector).
pH range
Depends on the pre-column heater (→ section 2.10, page 24), post-column cooler
(→ section 2.11, page 25), and column switching valve (→ section 7.3.4, page 107).
Buffer concentration
Depends on the pre-column heater, post-column cooler and/or column switching valve
SST: Typically up to 1 mol/L (< 0.1 mol/L chloride ions)
Ti/PEEK: Typically up to 1 mol/L (< 1 mol/L chloride ions)
Also observe the information about the solvent compatibility of the other UltiMate 3000
system modules. For more information, refer to the Operating Instructions for the
modules.
Page 12
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Operating Instructions

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Tcc-3000sdTcc-3000rs

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