Cleaning The Ion Block Components - Waters Xevo G2-XS QTof Overview And Maintenance Manual

Warning:
corrosive materials, dispose of all waste materials according to local environmental
regulations.
13. If the cover seal or cone gas O-ring shows signs of deterioration or damage, dispose of it in
accordance with local environmental regulations.

7.15.3 Cleaning the ion block components

Required materials
• Chemical-resistant, powder-free gloves
• Appropriately sized glass vessels in which to completely immerse components when
cleaning. Use only glassware not previously cleaned with surfactants.
• HPLC-grade (or better) methanol
• HPLC-grade (or better) water
• Formic acid
• Ultrasonic bath
• Oil-free nitrogen gas for drying (air-drying optional)
• Wash bottle containing HPLC-grade (or better) 1:1 methanol/water
• Large beaker
To clean the ion block components:
Warning:
To avoid personal contamination with biologically hazardous, toxic, and corrosive
materials, wear chemical-resistant, powder-free gloves when performing this procedure.
Warning:
To avoid injury when working with formic acid, which is extremely corrosive and toxic,
take extreme care handling it, and use a fume hood and suitable protective equipment.
1. Immerse the ion block and isolation valve in separate glass vessels containing 1:1
methanol/water.
Tip:
If the components are obviously contaminated, use 45:45:10 methanol/water/formic
acid.
2. Place the vessels in the ultrasonic bath for 30 minutes.
Note:
If you used formic acid in the cleaning solution, proceed to step 3. If not, go to step
4.
3. If you used formic acid in the cleaning solution, do as follows:
To avoid spreading contamination with biologically hazardous, toxic, and
March 31, 2021, 715004496 Ver. 04 (previously released as Rev. D)
Page 128