Cleaning The Ion Block Components - Waters Xevo TQ-S Operator's, Overview And Maintenance Manual

Cleaning the ion block components

Required materials
• Chemical-resistant, powder-free gloves.
• Appropriately sized glass vessels in which to completely immerse
components when cleaning. Use only glassware not previously cleaned
with surfactants.
• HPLC-grade (or better) methanol.
• HPLC-grade (or better) water.
• Formic acid.
• Ultrasonic bath.
• Source of oil-free, inert gas (for example, nitrogen) for drying (air-drying
optional).
• Wash bottle containing HPLC-grade (or better) 1:1 methanol/water.
• Large beaker.
To clean the ion block components:
Warning:
biohazardous and/or toxic materials. Always wear
chemical-resistant, powder-free gloves while performing this
procedure.
Warning:
extreme care, use a fume hood and suitable protective equipment.
1. Immerse the ion block and isolation valve in separate glass vessels
containing 1:1 methanol/water.
If the components are obviously contaminated, use 45:45:10
Tip:
methanol/water/formic acid.
2. Place the vessels in the ultrasonic bath for 30 minutes.
The ion block components can be contaminated with
Formic acid is extremely corrosive and toxic. Work with
Cleaning the ion block assembly 4-55