Cleaning The Ion Block Components - Waters Xevo TQ-S Operator's, Overview And Maintenance Manual

Cleaning the ion block components

Required materials
• Chemical-resistant, powder-free gloves.
• Appropriately sized glass vessels in which to completely immerse
components when cleaning. Use only glassware not previously cleaned
with surfactants.
• HPLC-grade (or better) methanol.
• HPLC-grade (or better) water.
• Formic acid.
• Ultrasonic bath.
• Source of oil-free, inert gas (for example, nitrogen) for drying (air-drying
optional).
• Wash bottle containing HPLC-grade (or better) 1:1 methanol/water.
• Large beaker.
Warning:
toxic materials, and to avoid spreading contamination to
uncontaminated surfaces, wear clean, chemical-resistant,
powder-free gloves when working with the ion block components.
Warning:
hood, and suitable protective equipment. Formic acid is extremely
corrosive and toxic.
To clean the ion block components:
1. Immerse the ion block and isolation valve in separate glass vessels
containing 1:1 methanol/water.
If the components are obviously contaminated, use 45:45:10
Tip:
methanol/water/formic acid.
2. Place the vessels in the ultrasonic bath for 30 minutes.
3. If you used formic acid in the cleaning solution, do as follows:
a. Rinse the components by immersing them separately in glass
vessels containing water and then placing the vessels in the
ultrasonic bath for 20 minutes.
To avoid personal contamination with biohazards or
To avoid injury, work with extreme care. Use a fume
February 28, 2014, 715002212 Rev. C
Cleaning the ion block assembly
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