Running The Mass Spectrometer At High Flow Rates - Waters Xevo TQ MS Operator's, Overview And Maintenance Manual

2 Preparing the Mass Spectrometer for Operation

Running the mass spectrometer at high flow rates

The ACQUITY UPLC system runs at high flow rates. To optimize desolvation,
and thus sensitivity, run the ACQUITY Xevo TQ MS system at appropriate
gas flows and desolvation temperatures. IntelliStart software automatically
sets these parameters when you enter a flow rate, according to the following
table.
Flow rate versus temperature and gas flow:
Flow rate
(mL/min)
0.000 to 0.020
0.020 to 0.100
0.101 to 0.300
0.301 to 0.500
> 0.500
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Source temp (°C)
150
150
150
150
150
Desolvation
temp (°C)
200
300
400
500
600
Desolvation gas
flow (L/h)
800
800
800
1000
1000