Running The Mass Spectrometer At High Flow Rates - Waters Xevo TQ-S Operator's, Overview And Maintenance Manual

Running the mass spectrometer at high flow rates

The ACQUITY UPLC system runs at high flow rates. To optimize desolvation,
and thus sensitivity, run the ACQUITY Xevo TQ-S system at appropriate gas
flows and desolvation temperatures. IntelliStart software automatically sets
these parameters when you enter a flow rate, according to the following table.
Flow rate versus temperature and gas flow:
Flow rate
(mL/min)
0.000 to 0.020
0.021 to 0.100
0.101 to 0.500
>0.500
If you are using an APCI interface, IntelliStart software automatically sets
the parameters according to the following table.
Flow rate versus IonSABRE II probe temperature and gas flow:
Flow rate
(mL/min)
0.000 to 0.020
0.021 to 0.500
>0.500
Source
temperature (°C)
150
150
150
150
IonSABRE II
probe
temperature (°C)
400
500
0
Desolvation
temperature (°C)
200
300
500
0
Desolvation gas
flow (L/h)
800
1000
1000
Starting the mass spectrometer
Desolvation gas
flow (L/h)
800
800
1000
1000
2-5