Troubleshooting - Waters ACQUITY UPLC M-Class System Manual

μSM-FL maintenance procedures: (Continued)
Maintenance
procedure
Replace the sample
syringe
Replace the injection
valve cartridge
TVM maintenance procedures:
Maintenance
procedure
Replace the column
Replace the valve
cartridge
Clean the device's
exterior with a soft,
lint-free cloth, or paper
dampened with water

Troubleshooting

When a malfunction occurs, you must systematically troubleshoot the system,
to isolate the problem.
Frequency
As part of the annual scheduled routine
maintenance and thereafter, as needed. These are
the typical failure modes:
• The sample syringe leak test fails.
• Air bubbles are in the syringe.
• A sample syringe hardware error message
appears.
As needed.
Frequency
As needed. The typical failure modes are as follows:
• High back pressure: the column causes a
high-pressure shutdown.
• Method requirements are not met, as evidenced
by poor peak shape, resolution between peaks
lost, tailing, etc. Perform a plate count to
establish column efficiency.
As needed.
Perform as part of annual routine scheduled
maintenance and when solvent or dust
accumulates.
March 10, 2014, 715003588 Rev. A
Troubleshooting
49