Trap Valve Manager; Detection - Waters ACQUITY UPLC M-Class System Manual

1 ACQUITY UPLC M-Class system

Trap valve manager

The trap valve manager (TVM) comprises two trapping valves and a
column-heater compartment. The compartment, to the right-hand side of the
chassis, extends outward in any position between 90° and 180°, plumbs into
an optional optical detector or is plumbed into a mass spectrometer.
The TVM accommodates several columns ranging from 75-μm I.D. to 2.1-mm
I.D., in lengths up to 25-cm.
The Trap Valve Manager Overview and Maintenance Guide, on the
See also:
documentation CD, for more information about this module.

Detection

Optical detection
The ACQUITY UPLC PDA and TUV are optical detectors that detect and
quantify concentrations of sample analyte. New flow cells, developed with
non-reactive wetted surfaces, are compatible with the operation of 300 μm to
1.0 mm I.D. columns.
The ACQUITY UPLC M-Class System documentation CD for the
See also:
following documents:
• ACQUITY UPLC TUV Detector Operator's Overview and Maintenance
Guide
• ACQUITY UPLC Photodiode Array and e
Operator's Overview and Maintenance Guide.
Mass detection
The ACQUITY UPLC M-Class system maximizes peak capacity, extending
the dynamic range of sample analysis. The ACQUITY UPLC M-Class system
can be combined with all types of mass spectrometers, whether analyzing
complex samples in wide-ranging matrices with a high resolution MS, or
quantifying peptides, metabolites, or other targeted experiments with tandem
MS. Engineered for the lowest dispersion, including an improved ESI
micro-probe design, and with an extended pressure envelope, complex
separations can be accelerated without compromising the chromatography.
When multiple microscale and UPLC systems connect to a single mass
spectrometer, you can switch between those systems using a software utility.
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λ Photodiode Array Detector