Waters ACQUITY UPLC M-Class System Manual page 48

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4 Maintaining the system
Solvent manager maintenance procedures: (Continued)
Maintenance
procedure
Replace the plunger
and seals
Replace the vent valve
cartridge
Clean the module's
exterior with a soft,
lint-free cloth, or paper
dampened with water
μSM-FL maintenance procedures:
Maintenance
procedure
Clean the module with
a soft, lint-free cloth,
or paper dampened
with water
Replace the needle seal As part of the annual scheduled routine
Replace the sample
needle
48
March 10, 2014, 715003588 Rev. A
Frequency
As part of the annual scheduled routine
maintenance and thereafter, as needed. The typical
failure modes are as follows:
• Late eluting peaks are exhibited after a dynamic
leak test was performed where the leak rate is
above the acceptable limit.
• Flow, from the seal wash effluent, during the
high-pressure dynamic leak test.
• The solvent manager exhibits low or erratic flow
rate or pressure pulsations.
As needed.
Perform as part of annual routine scheduled
maintenance and when solvent or dust
accumulates.
Frequency
Perform as part of annual routine scheduled
maintenance and when solvent or dust
accumulates.
maintenance and thereafter, as needed. The typical
failure modes are as follows:
• The needle seal readiness test fails.
• Peaks do not appear on your chromatogram.
• Peak areas are lower than expected.
When the needle breaks, when the error message
"Drawing sample rate excessive <value>" appears,
or the needle seal readiness test failed.

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