Μsample Manager - Fixed Loop; Sample Organizer; Trap Valve Manager; Detection - Waters ACQUITY UPLC M-Class System Manual

1.2.4 µSample Manager - Fixed Loop
The µSample Manager - Fixed Loop (µSM-FL) manages sample injections. It uses a fixed loop-
based mechanism to inject samples. After a puncture needle pierces the covering of a well or vial,
a sample needle extends through the puncture needle and aspirates the sample. The aspirated
sample is then drawn toward the sample loop while weak-wash solvent is simultaneously
dispensed through the needle, behind the sample. The wash syringe then pressurizes the needle
from the tip, compressing the air gaps around the sample and positioning the sample completely
within the loop. When the sample is in position, the injection valve is actuated to the inject
position, and high-pressure flow from the pump impels the sample onto the chromatographic
column.
The µSM-FL employs a thermal system that maintains a set temperature in the sample
compartment. When used in conjunction with the optional sample organizer, they create a
combined, thermally controlled compartment.
See also:
The µSample Manager - Fixed Loop Overview and Maintenance Guide on the
documentation CD for more information about this module.

1.2.5 Sample Organizer

The optional Sample Organizer enables automatic processing and increased throughput by
storing multiple microtiter or vial plates and transferring them to and from the µSM-FL.
The Sample Organizer's storage-shelf compartment can hold a selection of ANSI plates. A
heater/cooler thermally conditions the shelf compartment and maintains the temperature at a
specified set point.
See also:
The Sample Organizer Overview and Maintenance Guide on the documentation CD
for more information about this module.

1.2.6 Trap Valve Manager

The Trap Valve Manager (TVM) comprises two trapping valves and a column-heater
compartment. The column extends from the TVM arm and plumbs into an optional optical
detector or a mass spectrometer. In addition, the TVM accommodates several columns ranging
from 75-µm ID to 2.1-mm ID, in lengths up to 25 cm.
See also:
The Trap Valve Manager Overview and Maintenance Guide on the documentation CD
for more information about this module.

1.2.7 Detection

November 26, 2019, 715003588 Revision C
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