Auxiliary Solvent Manager; Μbinary Solvent Manager - Waters ACQUITY UPLC M-Class System Manual

• The system components are optimized for use with sub-2-µm, particle liquid chromatography,
and reduced fluid volumes.
• 100-nL, 10-mm path-length, light-guided TUV, and PDA detector flow cells deliver sensitivity
and resolution to ACQUITY UPLC M-Class applications on columns ranging from 300-µm to
1.0-mm ID.
• The columns, tubings, and fittings support flow rates for a gradient elution from 200nL/min to
100 µL/min at 103,421 kPa (1034 bar, 15,000 psi).
• With mass spectrometry, NanoLockSpray achieves exact mass measurement with columns
ranging from 75-µm to 1.0-mm ID.
• Solvent managers with flow control modules provide accurate NanoFlow rates. An optional
auxiliary solvent manager comprises two isocratic pumps. The A-side provides an additional
eluent with a flow rate range from 0.0 to 1.000 mL/min. The B-side provides NanoLockSpray
addition under flow control with a flow rate range from 0.0 to 100.0 µL/min.
• A micro-scale ESI probe in the ZSpray API interface delivers superior sensitivity. As column
ID decreases, this micro-probe reduces band-broadening to maintain chromatographic
integrity.

1.2.2 Auxiliary Solvent Manager

The Auxiliary Solvent Manager (ASM) is a high-pressure pump that provides pulse-free flow rates
at operating pressures as high as 103,421 kPa (1034 bar, 15,000 psi). The ASM consists of two
isocratic pumps, pump A and pump B. Each pump is fitted with two linear-drive actuators, which
together serve as a single reciprocating "serial" pump that delivers precise flow of a single
solvent. The solvent flows to the µSM-FL or column at an overall flow rate of 0.0 to 1000.0 µL/min
from pump A and 0.0 to 100.0 µL/min from pump B. Sometimes the ASM is also used to flow lock
mass directly into the mass spectrometer, usually from the B side.
See also:
The Auxiliary Solvent Manager Overview and Maintenance Guide on the
documentation CD for more information about this module.
1.2.3 µBinary Solvent Manager
The µBinary Solvent Manager (µBSM) is a high-pressure pump that provides steady (pulse-free)
solvent flow at flow rates ranging from 0.0 to 6.0 µL/min (under closed-loop control) or to 100.0
µL/min (under open-loop control) at 103,421 kPa (1034 bar, 15,000 psi).
See also:
The µBinary Solvent Manager Overview and Maintenance Guide on the
documentation CD for more information about this module.
November 26, 2019, 715003588 Revision C
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