Waters ACQUITY UPLC M-Class System Manual page 62

Table 4–2: Solvent manager maintenance procedures (continued)
Maintenance procedure
Replace the plunger and seals
Replace the vent valve cartridge
Clean the module's exterior with a soft, lint-
free cloth, or paper dampened with water
Table 4–3: µSM-FL maintenance procedures
Maintenance procedure
Clean the module with a soft, lint-free cloth,
or paper dampened with water
Replace the needle seal
Replace the sample needle
November 26, 2019, 715003588 Revision C
Page 62
Frequency
As part of the annual scheduled routine
maintenance and thereafter, as needed. The
typical failure modes are as follows:
• Late eluting peaks are exhibited after a
dynamic leak test is performed where the
leak rate is above the acceptable limit.
• Flow from the seal wash effluent during
the high-pressure dynamic leak test.
• The solvent manager exhibits low or
erratic flow rate or pressure pulsations.
As needed.
Perform as part of annual routine scheduled
maintenance and when solvent or dust
accumulates.
Frequency
Perform as part of annual routine scheduled
maintenance and when solvent or dust
accumulates.
As part of the annual scheduled routine
maintenance and thereafter, as needed. The
typical failure modes are as follows:
• The needle seal readiness test fails.
• Peaks do not appear on your
chromatogram.
• Peak areas are lower than expected.
When the needle breaks, when the error
message Drawing sample rate
excessive <value> appears, or the
needle seal readiness test fails.