Quality Control; Ism Classification: Ism Group 1 Class B - Waters ACQUITY UPLC M-Class System Manual

When calibrating mass spectrometers, consult the instrument's online Help system for calibration
instructions.

Quality control

Routinely run three QC samples that represent subnormal, normal, and above-normal levels of a
compound. If sample trays are the same or very similar, vary the location of the QC samples in
the trays. Ensure that QC sample results fall within an acceptable range, and evaluate precision
from day to day and run to run. Data collected when QC samples are out of range might not be
valid. Do not report these data until you are certain that the instrument performs satisfactorily.

ISM classification: ISM group 1 class B

This classification has been assigned in accordance with CISPR 11 Industrial Scientific and
Medical (ISM) instrument requirements.
Group 1 products apply to intentionally generated and/or used conductively coupled radio-
frequency energy that is necessary for the internal functioning of the equipment.
Class B products are suitable for use in both commercial and residential locations and can be
directly connected to a low voltage, power-supply network.
November 26, 2019, 715003588 Revision C
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