Waters ACQUITY UPLC M-Class System Manual page 61

Table 4–2: Solvent manager maintenance procedures (continued)
Maintenance procedure
Replace the in-line filter
Replace the accumulator check valve
cartridge
Replace solvent reservoir filters
Clean the air filter in the door
Replace the air filter in the door
November 26, 2019, 715003588 Revision C
Page 61
Frequency
As needed. The typical failure modes are as
follows:
• High back pressure: the in-line filter
causes a high-pressure shutdown. In this
case, disconnect the in-line filter. If the
system exhibits pressure decay,
determine the system pressure at known
conditions. Replace the frit or entire
check-valve assembly.
• Leaks are detected visibly or by peak
retention times that vary.
• Leaks are detected by high pre-sensor
leak rates as noted on the set pressure
diagnostic.
As part of the annual scheduled routine
maintenance and thereafter, as needed. The
typical failure modes are as follows:
• Late eluting peaks are exhibited after a
dynamic leak test is performed where the
leak rate is above the acceptable limit.
• The solvent manager exhibits a low or
erratic flow rate or pressure pulsations.
As part of the annual scheduled routine
maintenance and thereafter, as needed. The
typical failure modes are as follows:
• Slow baseline drift is exhibited.
• Retention times increase.
• The system exhibits low, erratic system
pressure.
Perform as part of your annual routine
scheduled maintenance and when solvent or
dust accumulates.
Perform as part of your annual routine
scheduled maintenance and when solvent or
dust accumulates.