Waters ACQUITY UPLC M-Class System Manual page 45

Tip:
To prevent band spreading, ensure that the tubing is fully bottomed in the fitting before
tightening the compression screw.
First-use tightening
Reinstalled
Long flats
Compression screw
Two-piece stainless steel ferrule
Tighten the fitting finger-tight, plus as much as an additional 1/6-turn using a 1/4-inch open-end
wrench.
Reinstalled tightening
November 26, 2019, 715003588 Revision C
Page 45