Configuring Maintenance Warnings - Waters ACQUITY UPLC M-Class System Manual

Suspected cause
µSM-FL temperature is too high or low.
Sample syringe draw speed set too high,
resulting in too little sample draw-up.
Sample diluent composition contains too much
organic, resulting in poor peak shape.
Vial position is incorrect.
Incorrect sample preparation and sample
composition resulting in, or due to, one or more
of the following:
• Sample concentration too low
• Sample is not completely in solution
• Volatile sample is evaporating
• Sample is degraded
• Sample precipitated over time
• Sample prepared incorrectly
• Sample buffers and acids inappropriate for
the injection method selected
Glassware incorrect or contaminated
Vial, vial cap or well plate cap mat failure or
malfunction.
Column viability in question.

4.4 Configuring maintenance warnings

Maintenance counters, if available for a particular component, provide information about real-time
usage that can help you determine when to schedule routine maintenance for specific
components. You can specify usage thresholds and maintenance warnings that alert you when a
component reaches a specified threshold. You can minimize unexpected failures and
unscheduled downtime during important work. For information explaining how to specify
maintenance warnings, consult the Waters console Help.
Possible solution
Adjust the µSM-FL sample compartment
temperature.
From the Method Editor, program a slower
draw speed.
Decrease organic in the sample diluent.
Program the correct vial position in the sample
list.
Select the appropriate sample preparation
method for the injection method selected and
remake if necessary.
See also:
Performance LC/MS and HPLC/MS Systems
on the documentation CD.
See also:
selector at
index.html.
See also:
use manual on the documentation CD.
November 26, 2019, 715003588 Revision C
Page 74
Controlling Contamination in Ultra
The Waters vials, filters, and plates
www.waters.com/app/selector/en/
The appropriate column care and