Abbott i-STAT 1 System Manual page 482

Test Limitations
The i-STAT ACT test is to be used with fresh venous or arterial whole blood samples. The presence
Kaolin
of exogenously added heparin, citrate, oxalate, or EDTA will interfere with test results. Poor technique in
sample collection may also compromise the results. Samples drawn from insufficiently flushed catheters
or from traumatic venipunctures may be contaminated with interfering substances. Samples should be
collected into plastic syringes or tubes. Collection into glass may prematurely activate coagulation resulting
in accelerated clotting times.
The analyzer should remain on a level surface with the display facing up during testing. If the analyzer is not
level, the ACT result may be affected by more than 10 %. A level surface includes running the handheld in
the downloader/recharger.
Hemodilution may affect test results.
Platelet dysfunction, hereditary or acquired, may affect the results of this test. This includes the
administration of pharmacological compounds known as platelet inhibitors which affect platelet function.
Factor deficiencies, dysprothrombinemias, other coagulopathies, and other pharmacological compounds
may also affect the results of this test.
The i-STAT ACT test is not affected by fibrinogen concentration in the range from 100 - 500 mg/dL, or
sample temperature from 15 - 37ºC.
Kaolin ACT - 6
Art: 715878-01M Rev. Date: 01-Jul-13