Abbott i-STAT 1 System Manual page 411

Method Comparison (mmol/L or mEq/L)
Beckman Synchron CX
n
Sxx
Syy
Slope
Int't
Sy.x
Xmin
Xmax
r
Factors Affecting Results*
Hemodilution of the plasma by more than 20% associated with priming cardiopulmonary bypass pumps,
plasma volume expansion or other fluid administration therapies using certain solutions may cause clinically
significant error on sodium, chloride, ionized calcium and pH results. These errors are associated with
solutions that do not match the ionic characteristics of plasma. To minimize these errors when hemodiluting
by more than 20%, use physiologically balanced multi-electrolyte solutions containing low-mobility anions
(e.g. gluconate).
Interference studies were based on CLSI guideline EP7-A2.
CLSI guideline unless otherwise indicated.
When added to a plasma pool the following substances (at the concentrations indicated) were
found to interfere with the i-STAT chloride assay:
Substance
Acetylcysteine
Bromide
Bromide (therapeutic)
Salicylate
Thiocyanate
Nithiodote (sodium thiosulfate)
The following substances are known not to significantly interfere with the i-STAT chloride assay at
the stated test concentrations:
Substance
Acetaminophen
Acetylcysteine (therapeutic)
Ascorbate
β-Hydroxybutyrate
Lactate
Salicylate (therapeutic)
Rev. Date: 15-Jul-16
3 Kodak Ektachem 700
®
189
1.27
0.88
0.99
-0.82
1.65
93
114
0.817
Test Concentration
(mmol/L)
10.2
37.5
2.5
7,8,9
4.34
6.9
16.7
Art: 714175-01O
142
0.41
0.90
0.88
14.6
1.84
63
128
0.914
Test concentrations used were as per the
6
Increased i-STAT Chloride results.
See Note 1 below.
Use another method.
See Note 2 Below.
Increased i-STAT Chloride results.
Use another method.
Increased i-STAT Chloride results.
Use another method.
Increased i-STAT Chloride results.
Use another method.
Increased i-STAT Chloride results.
15
See Note 4 below.
Test Conc.
Nova STAT Profile 5
®
192
0.89
0.88
0.93
4.3
2.33
96
117
0.752
Interference
(mmol/L)
1.32
0.30
10,11,12
0.34
6.0
13
6.6
0.5
14
CL - 3