Abbott i-STAT 1 System Manual page 435

Method Comparison (mmol/L)
Radiometer ICA1
n 47
Sxx 0.009
Syy 0.017
Slope 0.925
Int't 0.113
Sy.x 0.035
Xmin 0.46
Xmax 2.05
r 0.982
Cartridge Comparison
The performance characteristics of the sensors are equivalent in all cartridge configurations. System
difference analysis was performed on 24 patient samples using i-STAT CHEM8+ and i-STAT CG8+
cartridges. In the 0.46 - 1.23 mmol/L range, the average difference was 0.003.
Factors Affecting Results*
Venous stasis (prolonged tourniquet application) and forearm exercise may increase ionized calcium due to
a decrease in pH caused by localized production of lactic acid
increase in pH due to the loss of CO
Heparin binds calcium. Each unit of heparin added per mL of blood will decrease ionized calcium by
0.01 mmol/L. 5 Therefore, the correct ratio of heparin anticoagulant to blood must be achieved during
sample collection. Intravenous injection of 10,000 units of heparin has been shown in adults to cause a
significant decrease of ionized calcium of about 0.03 mmol/L.
devices when using i-STAT's aqueous control and calibration verification materials.
Hemodilution of the plasma by more than 20% associated with priming cardiopulmonary bypass pumps,
plasma volume expansion or other fluid administration therapies using certain solutions may cause clinically
significant error on sodium, chloride, ionized calcium and pH results. These errors are associated with
solutions that do not match the ionic characteristics of plasma. To minimize these errors when hemodiluting
by more than 20%, use physiologically balanced multi-electrolyte solutions containing low-mobility anions
(e.g., gluconate).
Rev. Date: 15-Jul-16
Nova STAT Profile
57
0.017
0.017
0.960
0.062
0.029
0.53
2.05
0.982
which will decrease ionized calcium.
2
Art: 714179-01P
5 . Exposing the sample to air will cause an
5 Use only unheparinized sample transfer
iCa - 3