Abbott i-STAT 1 System Manual page 474

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Performance of the i-STAT Celite ACT at lower levels of heparin is shown below with two "Low Range" ACT

methods included for comparison:

Medtronic LR-ACT, s

Test Limitations

ACT test is to be used with fresh venous or arterial whole blood samples. The presence

of exogenously added heparin, citrate, oxalate, or EDTA will interfere with test results. Poor technique in

sample collection may also compromise the results. Samples drawn from insufficiently flushed catheters

or from traumatic venipunctures may be contaminated with interfering substances. Samples should be

collected into plastic syringes or tubes. Collection into glass may prematurely activate coagulation resulting

in accelerated clotting times.

The i-STAT ACT test uses Celite brand diatomaceous earth as the activator of the intrinsic pathway. The

result may, therefore, be prolonged in the presence of aprotinin.

The test is not recommended for use

with patients receiving aprotinin.

Celite ACT - 6

Art: 714185-01P

Rev. Date: 01-Jul-13

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