Waters ACQUITY Isocratic Solvent Manager Overview And Maintenance Manual page 91

The inlet side of the filter is denoted by the inscription "INLET".
Note:
Inlet compression
fitting
4. Holding the 22-μL filter with the 5/8-inch, open-end wrench, disconnect
the outlet compression fittings using the 1/4-inch wrench.
5. Remove the old 22-μL filter from the bracket.
6. Unpack the new 22-μL filter.
7. Insert the new 22-μL filter into the bracket.
8. Reattach the compression fittings to the 22-μL filter, and tighten them
finger-tight plus an additional 1/6-turn, for existing fittings, or 3/4-turn
for new fittings.
Replacing the inline 22-µL filter
Location of outlet
compression fitting
September 26, 2013, 715004208 Rev. A 91