Changing The Split Ratio - Waters ACQUITY Isocratic Solvent Manager Overview And Maintenance Manual

2 Preparing for Operation
9. Reconnect the finger-tight fittings to the outlet and inlet of the degasser.
Recommendation:
250 psi) backpressure regulator assembly to the outlet of the optical
detector when splitting in an Alliance or ACQUITY UPLC system. For
an Alliance system, the backpressure regulator is included in the
Alliance splitter kit; for an ACQUITY UPLC system, the backpressure
regulator is included with the ACQUITY detector.

Changing the split ratio

Change the split ratio to adjust the amount of analytical flow split to the QDa
detector.
General guidelines
When using the ACQUITY UPLC and Alliance Flow-splitter kits, observe
these guidelines:
• If the signal intensity in the QDa detector is low, switch to a restrictor
module with a lower numeric label that allows more analytical flow to
the QDa detector.
• If the signal intensity in the QDa detector is high, switch to a restrictor
module with a higher numeric label that allows less analytical flow to
the QDa detector.
48 September 26, 2013, 715004208 Rev. A
Degasser
outlet
Waters recommends connecting a 1724 kPa (17 bar,
Degasser
inlet