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Uv Lamp (Optional); Scope-Ready Tm Package (Optional); Pure-Vu™ Seal - Labconco Cell Logic A2 User Manual

Biosafety cabinets
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UV Lamp (optional)

The optional UV lamp generates a primary wavelength of light of 254nm. A secondary
emission is in the visible (blue) wavelength, resulting in the characteristic blue color
while operating. UV light at this wavelength is biocidal, primarily by creating thymine
dimers in DNA. These dimers prevent the correct transcription of the DNA into RNA,
resulting in cellular death or viral inactivation. In order to be effective, the UV light must
directly strike the nucleic acid, and its effectiveness can be diminished or negated by
dissolved proteins or metals, or by other UV-opaque substances protecting the target
nucleic acid.
Because of its limitations, UV light should be used as an adjunct to good surface
disinfection practices. In order to achieve optimum performance from the UV lamp, it
should be replaced after 6,000 hours of operation or less, and the exterior surface of the
lamp should be kept clean and free of dust.
Note: The product records the number of hours of operation of the UV light. You can
program in the number of hours it will operate before a replacement message is
displayed.
Note: UV irradiation is absorbed by the tempered safety glass of the sash. Independent
research has shown that the level of UV irradiation on the outside of the cabinet's sash
is equal to background radiation levels.
Note: The UV sensitivity of a target organism varies, depending on the UV output of the
lamp, the genus and species of the organism, the medium the agent is suspended in,
etc. Contact the Health and Safety Officer at your facility for UV light use and
recommendations.
TM
Scope-Ready
Package (optional)
Models with the Scope-Ready package option allow a user-supplied microscope to be
integrated into the safety cabinet. On these models, two features work together to
assure containment and reduced vibration:
Pure-Vu™ Seal
The Pure-Vu Seal includes a 7 inch (178 mm) wide x 10 inch (254 mm) high sash cutout
that accommodates most microscopes' eyepieces. The clear, disposable eyepiece seal
prevents contaminants from escaping while providing ergonomic visibility into the
cabinet. The removable seal attaches tightly to an aerodynamic, epoxy-coated steel
collar. The unique teardrop shape of the aerodynamic collar design keeps contaminants
contained with the microscope in place. The Pure-Vu Seal conforms to both ASHRAE
110 and NSF 49 testing criteria.
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