Combined Appi/Apci Source; Appi Operation - Waters Xevo TQ-S Operator's, Overview And Maintenance Manual

Combined APPI/APCI source

Operate this optional, replacement source enclosure as APPI, APCI, or
dual-mode APPI/APCI. Where, dual-mode APPI/APCI performs rapid
switching between ionization modes.

APPI operation

In atmospheric pressure photoionization (APPI) mode, the source is fitted
with an IonSABRE II probe, and the APPI lamp drive assembly is advanced
into the source.
APPI mode:
IonSABRE II probe
Sample ions
Sample cone
Photons from
the UV lamp
The IonSABRE II probe introduces vaporized sample into the source where
photons generated by an ultra-violet (UV) lamp (mounted in the APPI lamp
drive assembly) produce sample ions. Direct photoionization of a sample
molecule occurs when the photon energy exceeds the ionization potential of
the sample molecule.
A repeller electrode (mounted on the APPI lamp drive assembly) deflects and
focuses the sample ions towards the sample cone.
UV lamp Repeller electrode
Sample molecules
APPI lamp drive assembly
Combined APPI/APCI source 3-11