General cleaning of the QIAcuity:
Mild Detergents (e.g., Mikrozid® AF sensitive)
25% ethanol
Disinfection
Ethanol-based disinfectants can be used for disinfection of surfaces: e.g., 25 g ethanol and 35 g
1-propanol per 100 g liquid or Mikrozid Liquid (Schülke & Mayr GmbH, cat. no. 109160).
Disinfectants based on glyoxal and quaternary ammonium salt can be used for e.g. 10 g glyoxal,
12 g lauryldimethylbenzylammonium chloride, 12 g myristyldimethylbenzylammonium chloride,
and 5–15% nonionic detergent per 100 g liquid, Lysetol
no. 107410, or DECON-QUAT
167-01).
Removal of RNase contamination
RNaseZap
®
RNase Decontamination Solution (Ambion, Inc., cat. no AM9780) can be used for
cleaning surfaces. RNaseZap can also be used to perform decontamination by spraying the
respective items.
Removal of nucleic acid contamination
DNA-ExitusPlus™ (AppliChem, cat. no. A7089,0100) can be used for cleaning surfaces. DNA-
ExitusPlus can also be used to perform decontamination by spraying the respective items. DNA-
ExitusPlus is very sticky and foamy. For this reason, after cleaning the items with DNA-ExitusPlus,
you must clean the items with a wet cloth several times, or rinse them with running water, until the
DNA-ExitusPlus is completely removed.
General instructions
Do not use spray bottles to spray cleaning or disinfectant liquids onto surfaces of the QIAcuity.
If solvents or saline, acidic, or alkaline solutions are spilt on the QIAcuity, wipe the spilt liquid
away immediately.
Follow manufacturer's safety instruction for handling cleaning agents.
Follow manufacturer's instruction for soaking time and concentration of the cleaning agents.
Important: Immersing for longer than the recommended soak time can harm the instrument.
QIAcuity User Manual 07/2020
AF (Gigasept
®
100, Veltek Associates, Inc., in the USA, cat. no. DQ100-06-
®
Instru AF in Europe, cat.
®
188