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Qiagen EZ2 Connect User Manual

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EZ2
®
Connect Fx User Manual
9003210, 9003220
QIAGEN GmbH
QIAGEN Strasse 1, 40724 Hilden, GERMANY
1124549
Sample to
Insight__
Connect and EZ2
September 2021

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Summary of Contents for Qiagen EZ2 Connect

  • Page 1 September 2021 Connect and EZ2 ® Connect Fx User Manual 9003210, 9003220 QIAGEN GmbH QIAGEN Strasse 1, 40724 Hilden, GERMANY 1124549 Sample to Insight__...

  • Page 2: Table Of Contents

    3.2.2 Hood ....................28 3.2.3 USB ports ....................29 3.2.4 RJ-45 Ethernet port and power cord socket ..........30 3.2.5 Ventilation openings ................31 3.2.6 Bar code scanner .................31 Internal features of the EZ2 ................32 EZ2 Connect and EZ2 Connect Fx User Manual 09/2021...
  • Page 3 4.3.4 Installation of Wi-Fi adapter (optional when using QIAsphere) ....48 4.3.5 Initial configuration of the EZ2 ...............48 4.3.6 Perform camera exposure calibration (for EZ2 Connect Fx) ......50 Operating Procedures .....................52 General information ..................55 5.1.1 Entering text and numbers ..............58 Starting the EZ2 ...................60 Configuring the EZ2 ..................61...
  • Page 4 Cleaning agents ..................105 6.1.1 Disinfecting the EZ2 ................107 6.1.2 Removing contamination ..............107 After run maintenance ................108 Daily maintenance ..................111 Weekly maintenance ................. 114 UV decontamination .................. 117 EZ2 Connect and EZ2 Connect Fx User Manual 09/2021...
  • Page 5 Danger lié à la chaleur ..................141 Radiations ......................141 Sécurité de maintenance ..................142 Symboles sur l’instrument EZ2 Connect ..............144 Appendix D – Sicherheitshinweise ................... 146 Sachgemäße Handhabung ................... 147 EZ2 Connect and EZ2 Connect Fx User Manual 09/2021...
  • Page 6 Abfallentsorgung ....................154 Gefahr durch mechanische Teile ................154 Gefahr durch Hitze....................155 Strahlung ......................155 Wartungssicherheit ....................156 Symbole auf dem EZ2 Connect Gerät ..............158 Document Revision History ....................160 EZ2 Connect and EZ2 Connect Fx User Manual 09/2021...

  • Page 7: Introduction

    Introduction Thank you for choosing the EZ2 Connect. We are confident it will become an integral part of your laboratory. This user manual describes the EZ2 Connect. Before using the EZ2 Connect, it is essential that you read this user manual carefully and pay attention to the safety information.

  • Page 8: General Information

    QIAGEN customers are a major source of information regarding advanced or specialized uses of our products. This information is helpful to other scientists as well as to the researchers at QIAGEN. We therefore encourage you to contact us if you have any suggestions about product performance or new applications and techniques.

  • Page 9: Intended Use Of The Ez2

    The EZ2 Connect and EZ2 Connect Fx systems are designed to perform automated isolation and purification of nucleic acids. The EZ2 is intended to be used only in combination with QIAGEN kits indicated for use with the EZ2 instrument for the applications described in the kit handbooks. The EZ2 system is intended for use by professional operators, such as technicians and physicians trained in molecular biological techniques and the operation of the EZ2 system.

  • Page 10: Safety Information

    (only applicable for CE-marked devices with an authorized representative established in the EU) and the regulatory authority in which the user and/or the patient is established. EZ2 Connect and EZ2 Connect Fx User Manual 09/2021...

  • Page 11: Proper Use

    Risk of personal injury and material damage Do not attempt to move the EZ2 during operation. Perform the maintenance as described in the Maintenance Procedures section. QIAGEN charges for repairs that are required due to incorrect maintenance. In case of emergency, power OFF the EZ2 at the power switch located in front of the instrument and unplug the power cord from the power outlet.
  • Page 12 Risk of explosion The EZ2 is intended for use with reagents and substances supplied with QIAGEN kits as outlined in respective Information for use. Use of other reagents and substances may lead to fire or explosion. If hazardous material is spilled on or inside the EZ2, the user is responsible for carrying out appropriate decontamination.

  • Page 13: Electrical Safety

    WARNING Risk of electric shock Do not open any panels on the EZ2. Risk of personal injury and material damage Only perform maintenance that is specifically described in this user manual. EZ2 Connect and EZ2 Connect Fx User Manual 09/2021...
  • Page 14 If liquid has spilled inside the instrument, switch off the instrument, disconnect it from the  power outlet, and contact QIAGEN Technical Services for advice before attempting troubleshooting or service activity. If the instrument becomes electrically unsafe, prevent other personnel from operating it and contact QIAGEN Technical Services.

  • Page 15: Operating Conditions

    WARNING Risk of explosion The EZ2 is intended for use with reagents and substances supplied with QIAGEN kits. Use of other reagents and substances may lead to fire or explosion. CAUTION Damage to the instrument Direct sunlight may bleach parts of the instrument, cause damage to plastic parts or interfere with the correct function of the load check.

  • Page 16: Biological Safety

    * OSHA — Occupational Safety and Health Organization (United States of America) ACGIH – American Conference of Government Industrial Hygienists (United States of America) † COSHH – Control of Substances Hazardous to Health (United Kingdom) ‡ EZ2 Connect and EZ2 Connect Fx User Manual 09/2021...

  • Page 17: Chemicals

    Note: If you work with volatile solvents, toxic substances, etc., you must provide an efficient laboratory ventilation system to remove vapors that may be produced. EZ2 Connect and EZ2 Connect Fx User Manual 09/2021...

  • Page 18: Waste Disposal

    To avoid contact with moving parts during the operation of the EZ2, the instrument must be operated with the hood closed. If the hood sensor or lock is not functioning correctly, contact QIAGEN Technical Services. EZ2 Connect and EZ2 Connect Fx User Manual 09/2021...

  • Page 19: Heat Hazard

    270 to 285 nm. This wavelength corresponds to ultraviolet light type C, which can be used for decontamination procedures. A mechanical lock ensures that the hood must be closed for operation of the UV LED. If the hood sensor or lock is not functioning correctly, contact QIAGEN Technical Services.

  • Page 20: 2.10 Maintenance Safety

    Risk of personal injury and material damage CAUTION Only perform maintenance that is specifically described in this user manual. Perform the maintenance as described in the Maintenance Procedures section. QIAGEN charges for repairs that are required due to incorrect maintenance. WARNING/...
  • Page 21 WARNING/ Risk of personal electric shock CAUTION Do not open any panels on the EZ2 instrument. Only perform maintenance as described in this user manual. EZ2 Connect and EZ2 Connect Fx User Manual 09/2021...

  • Page 22: 2.11 Symbols On The Ez2 Connect Instrument

    2.11 Symbols on the EZ2 Connect instrument The following symbols appear on the EZ2 Connect and EZ2 Connect Fx instruments. Symbol Location Description Heating system — Heat hazard — the temperature of the heating system can reach up to inside instrument 95ºC.
  • Page 23 Type plate on the back Serial number. of the instrument Type plate on the back Consult instructions for use. of the instrument Type plate on the back See warnings and precautions. of the instrument EZ2 Connect and EZ2 Connect Fx User Manual 09/2021...

  • Page 24: General Description

    General Description Principle The EZ2 is available in different variants. This user manual focuses on the EZ2 Connect and EZ2 Connect Fx. The EZ2 Connect performs fully automated nucleic acid purification from up to 24 samples in molecular biology applications using magnetic particle technology.

  • Page 25: External Features Of The Ez2

    External features of the EZ2 Figure 1. The front of the EZ2 instrument. Touchscreen Hood Power button USB port Note: Two additional USB ports are located on the rear of the touchscreen (not shown). EZ2 Connect and EZ2 Connect Fx User Manual 09/2021...
  • Page 26 Figure 2. The back of the EZ2 instrument. RJ-45 Ethernet port Power cord socket — including instrument main fuse Cooling air outlets Instrument type plate EZ2 Connect and EZ2 Connect Fx User Manual 09/2021...

  • Page 27: Touchscreen

    Graphical User Interface (GUI) is displayed on the touchscreen, allowing the user to operate the instrument, set up and start runs, perform maintenance procedures, monitor the instrument status, change settings, and view reports. Figure 3. EZ2 touchscreen display with GUI. EZ2 Connect and EZ2 Connect Fx User Manual 09/2021...

  • Page 28: Hood

    To avoid contact with moving parts during the operation of the EZ2, the instrument must be operated with the hood closed. If the hood sensor or lock is not functioning properly, contact QIAGEN Technical Services. Figure 4. The EZ2 with the hood closed.

  • Page 29: Usb Ports

    The bar code scanner is connected to the EZ2 using any one of the 3 available USB ports. Important: Use only the USB flash drive provided by QIAGEN. Do not connect other USB flash drive devices to USB ports Important: Do not remove the USB drive while downloading or transferring data or software to or from the instrument.

  • Page 30: Rj-45 Ethernet Port And Power Cord Socket

    Lethal voltages inside the instrument When the instrument is connected to line power, terminals may be live and opening covers or removing parts is likely to expose live parts. EZ2 Connect and EZ2 Connect Fx User Manual 09/2021...

  • Page 31: Ventilation Openings

    3 USB ports. The scanner is used for reading Q-Card and sample bar codes. For more information on how to use the bar code scanner, refer to the Using the bar code scanner section. EZ2 Connect and EZ2 Connect Fx User Manual 09/2021...

  • Page 32: Internal Features Of The Ez2

    Figure 6. Interior of the EZ2. Pipettor head Cartridge rack Tip rack Magnet module Camera Internal features not marked in the picture: — Heating system — UV LED lamp — Internal light EZ2 Connect and EZ2 Connect Fx User Manual 09/2021...

  • Page 33: Pipettor Head

    Figure 7. EZ2 pipettor head. EZ2 Connect and EZ2 Connect Fx User Manual 09/2021...

  • Page 34: Worktable

    3.3.2 Worktable The EZ2 worktable contains two movable EZ2 Connect Cartridge Rack that hold all the labware required for a protocol run, and the heating system, which controls the temperature of samples during a run.
  • Page 35 24. On the worktable, the cartridge rack is located behind the tip rack. It holds up to 24 reagent cartridges. For more information on how to load the EZ2 Connect Cartridge Rack, refer to the Loading the cartridge rack section.
  • Page 36 Figure 11. EZ2 Connect Tip Rack. The EZ2 Connect Tip Rack consists of two separate parts. The left part of the tip rack is used for labware in positions from 1 to 12. The right part of the tip rack is used for labware in positions 13 to 24.
  • Page 37 The tray is located underneath the tip and cartridge racks. Its role is to prevent contamination of the EZ2 that could be caused by liquids that are unintentionally spilled. The tray can be removed and cleaned as described in the Daily maintenance section. EZ2 Connect and EZ2 Connect Fx User Manual 09/2021...

  • Page 38: Magnet Module

    Magnet module The EZ2 magnet module consists of magnets that are used to capture particles that are present in the liquid aspirated into the filter-tips. Figure 15. The EZ2 magnet module. EZ2 Connect and EZ2 Connect Fx User Manual 09/2021...

  • Page 39: Camera

    Camera Figure 16. Camera module. The EZ2 Connect Fx version has a built-in camera that is used for load checks and reading bar codes from cartridges. Load checks are done before a protocol run starts. The camera checks if all the labware has been loaded in the correct positions, tubes are opened if required.

  • Page 40: Internal Light

    Moving parts To avoid contact with moving parts during the operation of the EZ2, the instrument must be operated with the hood closed. If the hood sensor or lock is not functioning correctly, contact QIAGEN Technical Services. 3.3.6 Internal light The EZ2 has a built-in LED light.

  • Page 41: Installation Procedures

    Note: It is recommended to plug the instrument directly into its own power outlet and to not share the power outlet with another lab equipment. WARNING Explosive atmosphere The EZ2 instrument is not designed for use in an explosive atmosphere. EZ2 Connect and EZ2 Connect Fx User Manual 09/2021...

  • Page 42: Power Requirements

    The EZ2 operates at: 100–240 V AC +/– 10%, 50/60 Hz, 1000 VA. Make sure the voltage rating of the EZ2 is compatible with the AC voltage available at the installation site. EZ2 Connect and EZ2 Connect Fx User Manual 09/2021...

  • Page 43: Grounding Requirements

    AC power cord that, when connected to an appropriate AC power outlet, grounds (earths) the instrument. To preserve this protection feature, do not operate the instrument from an AC power outlet that has no ground (earth) connection. EZ2 Connect and EZ2 Connect Fx User Manual 09/2021...

  • Page 44: Unpacking The Ez2

     Left and right EZ2 Connect Cartridge Rack  Left and right EZ2 Connect Tip Rack  Left and right EZ2 Connect Tip Rack - Flip Cap Tube (for EZ2 Connect Fx)  Power cord set  USB drive ...
  • Page 45 QIAGEN Technical Services. 12. Check that the EZ2 is not damaged and that there are no loose parts. If anything is damaged, contact QIAGEN Technical Services. Make sure that the EZ2 has equilibrated to ambient temperature before powering on. EZ2 Connect and EZ2 Connect Fx User Manual 09/2021...

  • Page 46: Installing The Ez2

    1. Remove the power cord from the foam packing material on top of the EZ2. Note: Only use the power cord that is supplied with the EZ2. 2. Ensure that the power switch is set to OFF. EZ2 Connect and EZ2 Connect Fx User Manual 09/2021...
  • Page 47 Intentional interruption is prohibited. Lethal voltages inside the instrument When the instrument is connected to line power, terminals may be live and opening covers or removing parts is likely to expose live parts. EZ2 Connect and EZ2 Connect Fx User Manual 09/2021...

  • Page 48: Installation Of External Barcode Scanner (Optional)

    3. From the Configuration menu under the System tab, you can modify the Device Name, Date and Time fields. You also find information on Software version, Serial number, and Firmware version. For further details, see the Setting basic system data section. EZ2 Connect and EZ2 Connect Fx User Manual 09/2021...
  • Page 49 Figure 19. The System configuration tab. 4. You may adjust settings of the EZ2 Connect according to your preferences through the Instrument Settings tab under the Configuration menu. For further details see the Changing Instrument settings section. Figure 20. Details on the Instrument setting tab.

  • Page 50: Perform Camera Exposure Calibration (For Ez2 Connect Fx)

    To avoid contact with moving parts during the operation of the EZ2, the instrument must be operated with the hood closed. If the hood sensor or lock is not functioning correctly, contact QIAGEN Technical Services. 1. Before first use in the final installation site, the camera exposure calibration must be performed.
  • Page 51 3. During the calibration routine, the following will be displayed: Figure 22. Camera exposure calibration is in progress message. Note: For support or technical advice regarding this please contact QIAGEN Technical Service Department or see our Technical Support Center at http://www.qiagen.com/service-and- support/technical-support.

  • Page 52: Operating Procedures

    External features of the EZ2 and Internal features of the EZ2 sections. The EZ2 is intended to be used only in combination with QIAGEN kits indicated for use with the EZ2 instrument for the applications described in the kit handbooks.
  • Page 53 WARNING Risk of explosion The EZ2 is intended for use with reagents and substances supplied with QIAGEN kits as outlined in respective Information for use. Use of other reagents and substances may lead to fire or explosion. CAUTION Damage to the instrument Ensure that the EZ2 is switched off before you manually move the mechanical components of the instrument.
  • Page 54 Hazardous materials and infectious agents The waste contains samples and reagents. This waste may contain toxic or infectious material and must be disposed of properly. Refer to your local safety regulations for proper disposal procedures. EZ2 Connect and EZ2 Connect Fx User Manual 09/2021...

  • Page 55: General Information

    Generating and save run reports  Changing instrument settings to customize your EZ2  Each screen of the GUI consists of three elements: the toolbar, the main content, and the footer. EZ2 Connect and EZ2 Connect Fx User Manual 09/2021...
  • Page 56 Figure 23. The home screen (for EZ2 Connect Fx) Figure 24. The home screen (for EZ2 Connect) EZ2 Connect and EZ2 Connect Fx User Manual 09/2021...
  • Page 57 The part of the screen where the main content of each view is displayed. Footer The footer shows the current date and time, the software version, and the name of user that is currently logged in. EZ2 Connect and EZ2 Connect Fx User Manual 09/2021...

  • Page 58: Entering Text And Numbers

    Caps Lock . Tap Caps Lock again to turn off the uppercase input mode. To see special characters, tap Special Characters . To go back to the alphabetic characters, tap ABC EZ2 Connect and EZ2 Connect Fx User Manual 09/2021...
  • Page 59 Some fields have requirements or restrictions that have to be followed. If the entered text does not match the requirements of the field, an error message appears, and the input is not accepted. To proceed, modify the text, so that it follows the requirements. EZ2 Connect and EZ2 Connect Fx User Manual 09/2021...

  • Page 60: Starting The Ez2

    To start the EZ2, switch on the instrument and log in, then follow the steps below: 1. Close the hood of the instrument. 2. Press the power button. The startup screen appears, and the instrument is initialized. After the initialization is done, the Login screen appears. EZ2 Connect and EZ2 Connect Fx User Manual 09/2021...

  • Page 61: Configuring The Ez2

    Note: If the number of failed login attempts exceeds the limit set by your administrator, your account is locked. To activate your account, contact your administrator. If you are the only administrator and your account is locked, contact QIAGEN Technical Support. Configuring the EZ2 Administrators of the EZ2 can adjust instrument settings, manage users, upload and delete protocols, update software and configure network connectivity.

  • Page 62: Setting Basic System Data

    To select a specific date, tap the day on the calendar. To confirm your selection, tap Accept. EZ2 Connect and EZ2 Connect Fx User Manual 09/2021...

  • Page 63: Changing Instrument Settings

    You can adjust the settings of the EZ2 according to your preferences. Note: Only Administrators can change Instrument settings. To modify Instrument settings, follow the steps below: 1. Tap the Configuration icon on the toolbar and tap the Instrument settings tab. EZ2 Connect and EZ2 Connect Fx User Manual 09/2021...

  • Page 64: Managing Users

    EZ2 user management allows you to create and edit user accounts with two different roles: administrator and operator. Note: The EZ2 Connect Fx version has an additional advanced user role who can create shortcuts. When you use the EZ2 for the first time, a default user (Admin) is pre-installed and configured.
  • Page 65 1. Tap the Configuration icon on the toolbar and tap the User management tab. Existing users are shown in the table. Figure 33. The User Management tab. 2. To add a new user, tap New. The Create new account dialog is shown. EZ2 Connect and EZ2 Connect Fx User Manual 09/2021...
  • Page 66 Retype password field. The password must meet the criteria displayed in the dialog. To modify the password policy, refer to the Managing user security section. EZ2 Connect and EZ2 Connect Fx User Manual 09/2021...
  • Page 67 Editing an existing user account Note: Only administrators can edit user accounts. 1. Tap the Configuration icon on the toolbar and tap the User management tab. Existing users are shown in the table. EZ2 Connect and EZ2 Connect Fx User Manual 09/2021...
  • Page 68 2. Tap the table row that corresponds to the user whose profile you want to edit. The Edit user account dialog appears. Figure 37. Edit user account dialog. 3. To edit the First name or Last name, tap the respective boxes and modify the contents using the on-screen keyboard. EZ2 Connect and EZ2 Connect Fx User Manual 09/2021...
  • Page 69 Deleting a user Note: Only administrators can delete user accounts. 1. Tap the Configuration icon on the toolbar and tap the User management tab. Existing users are shown in the table. EZ2 Connect and EZ2 Connect Fx User Manual 09/2021...
  • Page 70 2. Tap the table row that corresponds to the user you want to delete. 3. Tap Delete. A confirmation dialog is shown. Figure 40. Delete user confirmation dialog. 4. To confirm the account deletion, tap Yes. EZ2 Connect and EZ2 Connect Fx User Manual 09/2021...

  • Page 71: Changing Password

    For more information on how to change passwords of other users, refer to the Editing an existing user account section. Note: For cybersecurity reasons, an operator must change the password provided by the administrator upon first login. EZ2 Connect and EZ2 Connect Fx User Manual 09/2021...

  • Page 72: Managing User Security

    5. Tap Change password. 5.3.5 Managing user security Administrators can change the password policy for all user roles, as well as change the settings for password expiration and limit incorrect login attempts. EZ2 Connect and EZ2 Connect Fx User Manual 09/2021...
  • Page 73 Incorrect login attempts field. It is recommended to set to at least 2 incorrect attempts. Otherwise, one typographical error will lock your account. 7. Tap Accept to save all changes, or tap Cancel to restore previously saved settings. EZ2 Connect and EZ2 Connect Fx User Manual 09/2021...

  • Page 74: Installing New Protocols

    Note: System Configuration is only available to users with administrator role. 1. Plug in a USB flash drive with the newest software version. 2. Tap the Configuration icon on the toolbar and tap the System configuration tab. EZ2 Connect and EZ2 Connect Fx User Manual 09/2021...
  • Page 75 Figure 45. System Configuration tab. 3. Tap Check for updates. 4. Start the installation by choosing the software package and tap Accept. 5. After installation is finished, follow the restart instruction of the machine. EZ2 Connect and EZ2 Connect Fx User Manual 09/2021...

  • Page 76: Configuring Network And Qiasphere Base Connections

    Note: LAN tab is only available to users with administrator role. 1. Tap the Configuration icon on the toolbar and tap the LAN tab. Figure 46. The LAN tab. 2. Enter IP address. 3. Enter Subnet mask. 4. Tap Accept. EZ2 Connect and EZ2 Connect Fx User Manual 09/2021...
  • Page 77 1. Tap the Configuration icon on the toolbar and tap the Tap Wi-Fi tab. Figure 47. The Wi-Fi tab. 2. To search for available networks, tap Scan. The signal strength, encryption type and name of each network is shown. EZ2 Connect and EZ2 Connect Fx User Manual 09/2021...
  • Page 78 Note: If you failed to connect to the network several times despite entering the correct password, it is recommended to restart the instrument. Note: In case of errors, refer to the Troubleshooting section for more information. EZ2 Connect and EZ2 Connect Fx User Manual 09/2021...
  • Page 79 7. To view additional information about the network, or to change its password, tap Advanced. To go back to the Wi-Fi tab, tap Back. To change the password, tap Change password. To disconnect from the network, tap Disconnect. Figure 50. Network settings dialog. EZ2 Connect and EZ2 Connect Fx User Manual 09/2021...
  • Page 80 For more details on the QIAsphere Base network configuration and how to connect both devices with each other, refer to the QIAsphere Base user manual which is available at www.qiagen.com. Only users assigned the role Administrator can change the network configuration. It is recommended to consult your network administrator when configuring the network.

  • Page 81: Setting Up A Protocol Run

    Important: Before starting a protocol run, read the relevant QIAGEN kit handbook and follow the instructions on sample storage, handling and preparation provided in the handbook.

  • Page 82: Selecting A Kit

    To select a protocol that is compatible with the kit selected in the Select kit step, tap a protocol in the Select protocol pane. Note: If there is only one available option, it is selected automatically. EZ2 Connect and EZ2 Connect Fx User Manual 09/2021...

  • Page 83: Defining Parameters

    To return to the previous screen, tap Back. To cancel the protocol, tap Cancel. 5.4.4 Defining parameters To set values for protocol parameters, tap the box next to each parameter in the Define parameters pane. EZ2 Connect and EZ2 Connect Fx User Manual 09/2021...

  • Page 84: Selecting Sample Positions

    To select the positions of your samples, tap the relevant rows on the worktable diagram or tap the corresponding row numbers underneath the diagram. The selected positions are highlighted. To select or deselect all positions, use the Select all toggle. EZ2 Connect and EZ2 Connect Fx User Manual 09/2021...
  • Page 85 After you select at least one sample position, the Next button is enabled. To proceed to the Enter sample IDs step, tap Next. To return to the previous screen, tap Back. To cancel the protocol, tap Cancel. EZ2 Connect and EZ2 Connect Fx User Manual 09/2021...

  • Page 86: Entering Sample Ids

    XX is the sample number. To generate the Sample IDs, you must press the Generate missing sample IDs button. Figure 57. Enter sample IDs step. EZ2 Connect and EZ2 Connect Fx User Manual 09/2021...
  • Page 87 Figure 58. Changing the sample ID. There is an 80-character limit for the Sample ID field. Tap Accept to save the changes, or tap Cancel to go back to the Enter sample IDs screen. EZ2 Connect and EZ2 Connect Fx User Manual 09/2021...
  • Page 88 Cancel to go back to the Enter sample IDs screen. To proceed to the Load the cartridge rack step, tap Next. To return to the previous screen, tap Back. To cancel the protocol, tap Cancel. EZ2 Connect and EZ2 Connect Fx User Manual 09/2021...

  • Page 89: Loading The Ez2 Connect Cartridge Rack

    Figure 60. Load the cartridge rack step. To proceed to the Load the tip rack step, tap Next. To return to the previous screen, tap Back. To cancel the protocol, tap Cancel. EZ2 Connect and EZ2 Connect Fx User Manual 09/2021...

  • Page 90: Loading The Ez2 Connect Tip Rack

    To proceed to the start of the protocol, tap Next. Before the run starts, you will see an overview of the selections you made during the run setup process. To return to the previous screen, tap Back. To cancel the protocol, tap Cancel. EZ2 Connect and EZ2 Connect Fx User Manual 09/2021...

  • Page 91: Canceling The Protocol Run Setup

    After successfully completing all the steps of the protocol run setup, you can start the run, and, optionally, add the protocol to your favorites. During the protocol run, you can monitor its progress. Ongoing steps are displayed on the screen. EZ2 Connect and EZ2 Connect Fx User Manual 09/2021...
  • Page 92 Figure 64. Close the hood dialog. 4. For EZ2 Connect Fx: If your instrument has a built-in camera, a load check is performed. For more information about the load check, refer to the Load check section. The run will start after the check is completed.

  • Page 93: Load Check

    Note: The load check feature is only available in EZ2 Connect Fx instruments. The EZ2 Connect Fx comes with a built-in camera, which checks if you have loaded all of the cartridges and labware into the correct positions on the worktable. However, the content of the labware in the tip rack is not checked, so you must make sure that you have carefully followed the instructions related to the protocol you are running.
  • Page 94 Back. The Load the tip rack screen is shown. Once you correctly load the worktable, tap Next in the Load the tip rack screen. The load check procedure starts again. Note: In case of repeated load check failure, please recalibrate the camera (refer to section 6.6). EZ2 Connect and EZ2 Connect Fx User Manual 09/2021...

  • Page 95: End Of The Protocol Run

    If after run maintenance is completed, tap the check box to transfer the maintenance status into the run report. For more information on how to save a run report, refer to the Saving a run report section. EZ2 Connect and EZ2 Connect Fx User Manual 09/2021...

  • Page 96: Aborting A Protocol Run

    1. In the Protocol run in progress screen, tap Abort run. A confirmation dialog appears. 2. Tap Yes to stop the run, or tap No to go back to the Protocol run in progress screen. Figure 69. Aborting protocol run dialog. EZ2 Connect and EZ2 Connect Fx User Manual 09/2021...
  • Page 97 4. Tap Finish to end the run and go back to the Home screen. A run report is generated. For more information on how to save a run report, refer to the Saving a run report section. Figure 71. Protocol run aborted screen. EZ2 Connect and EZ2 Connect Fx User Manual 09/2021...

  • Page 98: Sample Recovery

    Daily maintenance section. Sample recovery In case of a run failure the EZ2 Connect Fx provides a recovery feature which allows localization and recovery of the sample. Figure 72. Protocol run failed screen.

  • Page 99: 5.10.1 Run Report Contents

    These actions are described in the Loading the cartridge rack and Loading the tip rack screens of the protocol run setup process, and in the kit handbooks. EZ2 Connect and EZ2 Connect Fx User Manual 09/2021...

  • Page 100: 5.11.1 Loading And Unloading The Cartridge Rack

    For more information on disinfecting and removing contamination, refer to the Cleaning agents, Disinfecting the EZ2, and Removing contamination sections. 4. Place the cartridge rack sections back in the instrument. EZ2 Connect and EZ2 Connect Fx User Manual 09/2021...

  • Page 101: 5.11.2 Loading And Unloading The Tip Rack

    1. Remove one or both sections of the tip rack from the worktable. To remove a tip rack section, grab both sides of the section and gently pull up. 2. Remove the labware from the tip rack and dispose of any unnecessary labware, according to local safety regulations. EZ2 Connect and EZ2 Connect Fx User Manual 09/2021...
  • Page 102 For more information on disinfecting and removing contamination, refer to the Cleaning agents, Disinfecting the EZ2, and Removing contamination sections. 4. Place the tip rack sections back in the instrument. EZ2 Connect and EZ2 Connect Fx User Manual 09/2021...

  • Page 103: 5.12 Using The Bar Code Scanner

    Figure 73. Scanning the information into the Instrument. WARNING Risk of personal injury Hazard Level 2 laser light: Do not stare into the light beam when using handheld bar code scanner. EZ2 Connect and EZ2 Connect Fx User Manual 09/2021...

  • Page 104: 5.13 Logging Out And Switching The Instrument Off

    To switch the instrument off, press the power button. Note: It is not recommended to switch the instrument off when a protocol run, or maintenance procedure are in progress Figure 74. Location of the Log out button. EZ2 Connect and EZ2 Connect Fx User Manual 09/2021...

  • Page 105: Maintenance Procedures

    The surfaces and removable parts of the EZ2 must be cleaned and disinfected with compatible detergents and disinfectants. Please follow the instructions provided by the manufacturer of such materials to safely clean the instrument. EZ2 Connect and EZ2 Connect Fx User Manual 09/2021...
  • Page 106 WARNING Risk of electric shock Do not open any panels on the EZ2. Risk of personal injury and material damage Only perform maintenance that is specifically described in this user manual. EZ2 Connect and EZ2 Connect Fx User Manual 09/2021...

  • Page 107: Disinfecting The Ez2

    The EZ2 could be contaminated during operation. To remove the contamination, use appropriate decontamination solutions. In case of RNAse contamination, the RNaseZap RNase Decontamination Solution (Ambion, Inc., ® cat. no AM9780) can be used for cleaning surfaces and submerging worktable items. RNaseZap EZ2 Connect and EZ2 Connect Fx User Manual 09/2021...

  • Page 108: After Run Maintenance

    After run maintenance is required after each run on the EZ2. The EZ2 must only be operated by qualified personnel who have been appropriately trained. Servicing of the EZ2 must only be performed by QIAGEN Field Service specialists. WARNING Moving parts To avoid contact with moving parts during the operation of the EZ2, the instrument must be operated with the hood closed.
  • Page 109 After running a protocol, clean the piercing unit of the pipettor head. 1. Remove all sample preparation waste and discard it according to your local safety regulations. 2. Remove the eluates and store them appropriately 3. Close the hood EZ2 Connect and EZ2 Connect Fx User Manual 09/2021...
  • Page 110 6. Wipe the piercing unit using a soft tissue moistened with 70% ethanol. The piercing unit is sharp. Two pairs of gloves are recommended. Figure 76. Cleaning the EZ2 piercing unit. EZ2 Connect and EZ2 Connect Fx User Manual 09/2021...

  • Page 111: Daily Maintenance

    Moving parts To avoid contact with moving parts during the operation of the EZ2, the instrument must be operated with the hood closed. If the hood sensor or lock is not functioning correctly, contact QIAGEN Technical Services WARNING Moving parts Avoid contact with moving parts during operation of the EZ2.
  • Page 112 Important: Before starting the daily maintenance procedure, complete the After run maintenance. 1. On the touchscreen, tap Maintenance. 2. Tap Daily. The date of the last finished procedure is shown on the screen. EZ2 Connect and EZ2 Connect Fx User Manual 09/2021...
  • Page 113 12. Wipe the instrument racks with 70% ethanol, and then with distilled water. 13. Lightly wipe the O-rings of the tip adapters with a lint-free tissue to remove any residual liquid. EZ2 Connect and EZ2 Connect Fx User Manual 09/2021...

  • Page 114: Weekly Maintenance

    1. On the touchscreen, tap Maintenance. 2. Tap Weekly maintenance. The date of the last procedure, and the date of the next due date of the weekly maintenance are shown on the screen. EZ2 Connect and EZ2 Connect Fx User Manual 09/2021...
  • Page 115 There should not be a gap. Excess or insufficient grease can affect the performance of the EZ2. Note: The opening in the nub of the pipettor should be checked after greasing to ensure no grease is present within the opening. EZ2 Connect and EZ2 Connect Fx User Manual 09/2021...
  • Page 116 Figure 79. Placing a filter-tip onto the pipettor head. EZ2 Connect and EZ2 Connect Fx User Manual 09/2021...

  • Page 117: Uv Decontamination

    Important: Before starting the UV decontamination, complete the After run maintenance. 1. On the touchscreen, tap Maintenance. 2. Tap UV Run. The date of the last procedure is shown on the screen. EZ2 Connect and EZ2 Connect Fx User Manual 09/2021...
  • Page 118 Figure 80. Manual UV Run screen. 3. Select the number of decontamination cycles. The required decontamination time depends on the biological material processed on the device. 4. To begin the procedure, tap Start. EZ2 Connect and EZ2 Connect Fx User Manual 09/2021...

  • Page 119: Servicing

    Servicing Contact your local QIAGEN Technical Service or your local distributor for more information about flexible Service Support Agreements from QIAGEN. WARNING/ Risk of personal injury and material damage CAUTION Improper use of the EZ2 may cause personal injuries or damage to the instrument.

  • Page 120: Troubleshooting

     Support package  This information will help you and your QIAGEN Technical Service Specialist to deal most efficiently with your issue. Note: Information about the latest software and protocol versions can be found at www.qiagen.com. In some cases, updates may be available for addressing specific problems.
  • Page 121 3. Tap Create and download in the Support Package section. Figure 82. Data tab. 4. The support package is now saved on the USB flash drive. EZ2 Connect and EZ2 Connect Fx User Manual 09/2021...

  • Page 122: Operation

    Start UV decontamination. Make sure samples and cartridge rack were handled properly. Update fails Restart the device and try to start the update again. Make sure you use the QIAGEN USB flash drive. USB flash drive should stay plugged in during the whole update procedure.

  • Page 123: Glossary

    Error code A number that represents an error of the EZ2. EZ2 kits Kits supplied by QIAGEN containing reagents, reagent cartridges and plasticware for use with EZ2 instruments. Filter-tip Labware that is picked up by a tip adapter during operation of the EZ2. Liquid is aspirated into and dispensed from a filter-tip.

  • Page 124: Technical Specifications

    Technical Specifications QIAGEN reserves the right to change specifications at any time. Operating conditions Power 100−240 V AC, 50/60 Hz, 1000 VA Mains supply voltage fluctuations are not to exceed 10% of nominal supply voltages. Fuse AC Inlet: T4A H 250 V...

  • Page 125: Mechanical Data And Hardware Features

    Attach to the tip adapters of the pipettor head to allow liquid aspiration and dispensation. Capacity of 20–1000 μl. The EZ2 accommodates up to 48 tip holders in 2 rows, each containing a filter-tip, in the tip rack on the worktable. EZ2 Connect and EZ2 Connect Fx User Manual 09/2021...
  • Page 126 800 pixels. Camera Monochrome camera. The USB interface provide power and communication. Sensor resolution is 0.34 MP. Width: 24 mm (0.94 in.) Height: 34 mm (1.34 in.) Depth: 39 mm (1.54 in.) EZ2 Connect and EZ2 Connect Fx User Manual 09/2021...

  • Page 127: Declaration Of Conformity

    Appendix A Declaration of Conformity Name and address of the legal manufacturer QIAGEN GmbH QIAGEN Strasse 1 40724 Hilden Germany An up-to-date declaration of conformity can be requested from QIAGEN Technical Services. EZ2 Connect and EZ2 Connect Fx User Manual 09/2021...

  • Page 128: Waste Electrical And Electronic Equipment (Weee)

    Recycling can be provided by QIAGEN upon request at additional cost. In the European Union, in accordance with the specific WEEE recycling requirements and where a replacement product is being supplied by QIAGEN, free recycling of its WEEE-marked electronic equipment is provided.

  • Page 129: California Proposition 65 Warning

    Representations and warranties made by any person, including representatives of QIAGEN, which are inconsistent or in conflict with the conditions in this warranty shall not be binding upon the Company unless produced in writing and approved by an officer of QIAGEN.

  • Page 130: Appendix B - Ez2 Accessories

    For up-to-date licensing and product-specific disclaimers, see the respective QIAGEN kit handbook or user manual. QIAGEN kit handbooks and user manuals are available at www.qiagen.com or can be requested from QIAGEN Technical Services or your local distributor. EZ2 Connect and EZ2 Connect Fx User Manual 09/2021...

  • Page 131: Appendix C - Consignes De Sécurité

    Appendix C – Consignes de sécurité Avant d’utiliser le EZ2 Connect, il est impératif de lire attentivement ce manuel et de porter une attention particulière aux consignes de sécurité. Afin de garantir un fonctionnement de l’appareil en toute sécurité et de maintenir l’appareil en bon état de marche, il est impératif de suivre les instructions et consignes de sécurité...

  • Page 132: Utilisation Appropriée

    Risque de dommages corporels et matériels Ne pas essayer de déplacer l’EZ2 pendant qu’il est en marche. Procéder à la maintenance comme décrit à la section Maintenance Procedures. QIAGEN facture les réparations dues à une maintenance inappropriée. En cas d’urgence, éteindre l’EZ2 à l’aide de l’interrupteur d’alimentation situé à l’avant de l’instrument et débrancher le câble d’alimentation de la prise secteur.
  • Page 133 AVERTISSEMENT Risque d’explosion L’EZ2 est conçu pour être utilisé avec les réactifs et les substances fournis avec les kits QIAGEN, comme indiqué dans le mode d’emploi correspondant. L’utilisation d’autres réactifs et substances peut provoquer un incendie ou une explosion. Si des substances dangereuses sont renversées sur ou à l’intérieur du EZ2, l’utilisateur porte l’entière responsabilité...

  • Page 134: Sécurité Électrique

    Avant de mettre l’instrument SOUS tension, veiller à utiliser la bonne tension d’alimentation. L’utilisation d’une tension d’alimentation incorrecte risque d’endommager les composants électroniques. Pour connaître la tension d’alimentation recommandée, consulter les spécifications indiquées sur la plaque signalétique de l’instrument. EZ2 Connect and EZ2 Connect Fx User Manual 09/2021...
  • Page 135 AVERTISSEMENT Risque d’électrocution Ne pas ouvrir pas les panneaux de l’EZ2. Risque de dommages corporels et matériels Effectuer uniquement la maintenance spécifiquement décrite dans le présent manuel d’utilisation. EZ2 Connect and EZ2 Connect Fx User Manual 09/2021...
  • Page 136 Si un liquide s’est répandu à l’intérieur de l’appareil, éteignez-le, déconnectez-le de la prise  secteur et prenez contact avec les services techniques QIAGEN pour obtenir des conseils avant de tenter un dépannage ou une activité de service. Si l’instrument présente un danger électrique, empêcher le reste du personnel de s’en servir et contacter les services techniques QIAGEN.

  • Page 137: Conditions De Fonctionnement

    être obstruées. AVERTISSEMENT Risque d’explosion L’EZ2 est conçu pour être utilisé avec les réactifs et substances fournis avec les kits QIAGEN. L’utilisation d’autres réactifs et substances peut provoquer un incendie ou une explosion. ATTENTION Détérioration de l’instrument La lumière directe du soleil peut blanchir certaines parties de l’instrument endommager les pièces en plastique ou nuire au bon fonctionnement du...

  • Page 138: Sécurité Biologique

    ACGIH – American Conference of Government Industrial Hygienists (Conférence américaine des hygiénistes industriels † gouvernementaux) (États-Unis d’Amérique). COSHH – Control of Substances Hazardous to Health (Contrôle des substances dangereuses pour la santé) (Royaume- ‡ Uni). EZ2 Connect and EZ2 Connect Fx User Manual 09/2021...

  • Page 139: Produits Chimiques

    Ne pas utiliser de produit à base d’eau de Javel pour désinfecter les accessoires de laboratoire usagés. Le contact de l’eau de Javel avec des sels provenant des tampons peut produire des vapeurs toxiques. EZ2 Connect and EZ2 Connect Fx User Manual 09/2021...

  • Page 140: Élimination Des Déchets

    Pour éviter tout contact avec des pièces en mouvement pendant le fonctionnement du EZ2, l’instrument doit être utilisé avec le capot fermé. Si le capteur ou le verrou du capot ne fonctionne pas correctement, contacter les services techniques QIAGEN. EZ2 Connect and EZ2 Connect Fx User Manual 09/2021...

  • Page 141: Danger Lié À La Chaleur

    C, qui peut être utilisée pour des procédures de décontamination. Un verrou mécanique veille à ce que le capot soit fermé pour le fonctionnement de la LED à UV. Si le capteur ou le verrou du capot ne fonctionne pas correctement, contacter les services techniques QIAGEN. AVERTISSEMENT Rayonnement UV Éviter de regarder directement la lumière UV.

  • Page 142: Sécurité De Maintenance

    Risque de dommages corporels et matériels ATTENTION Effectuer uniquement la maintenance spécifiquement décrite dans le présent manuel d’utilisation. Procéder à la maintenance comme décrit à la section Maintenance Procedures. QIAGEN facture les réparations dues à une maintenance inappropriée. AVERTISSEMENT/ Risque de dommages corporels et matériels ATTENTION L’utilisation inappropriée de l’instrument EZ2 peut entraîner des accidents...
  • Page 143 AVERTISSEMENT/ Risque d’électrocution personnelle ATTENTION Ne pas ouvrir les panneaux de l’instrument EZ2. Effectuer la maintenance uniquement de la manière décrite dans le présent manuel d’utilisation. EZ2 Connect and EZ2 Connect Fx User Manual 09/2021...

  • Page 144: Symboles Sur L'instrument Ez2 Connect

    Symboles sur l’instrument EZ2 Connect Les symboles suivants figurent sur les instruments EZ2 Connect et EZ2 Connect Fx. Symbole Emplacement Description Système de Danger lié à la chaleur : la température du système de chauffage peut chauffage : intérieur atteindre 95 ºC.
  • Page 145 Plaque signalétique à Numéro de série. l’arrière de l’instrument Plaque signalétique à Lire le mode d’emploi. l’arrière de l’instrument Plaque signalétique à Se reporter aux avertissements et précautions. l’arrière de l’instrument EZ2 Connect and EZ2 Connect Fx User Manual 09/2021...

  • Page 146: Appendix D - Sicherheitshinweise

    Appendix D – Sicherheitshinweise Lesen Sie dieses Handbuch sorgfältig durch, bevor Sie den EZ2 Connect benutzen. Beachten Sie dabei insbesondere die Sicherheitshinweise. Die Gebrauchsanweisungen und Sicherheitshinweise im Handbuch müssen befolgt werden, um einen sicheren Betrieb des Geräts zu gewährleisten und das Gerät in einem sicheren Zustand zu erhalten.

  • Page 147: Sachgemäße Handhabung

    Bewegen Sie den EZ2 auf keinen Fall während des Betriebs. Führen Sie alle Wartungsarbeiten gemäß den Anweisungen im Abschnitt Maintenance Procedures dieses Handbuchs durch. QIAGEN stellt Reparaturen, die auf nicht fachgerecht durchgeführte Wartungsmaßnahmen zurückzuführen sind, in Rechnung. Schalten Sie den EZ2 im Notfall am Netzschalter an der Front des Geräts aus und ziehen Sie das Netzkabel aus der Netzsteckdose.
  • Page 148 Stellen Sie sicher, dass der EZ2 ausgeschaltet ist, bevor Sie mechanische Komponenten des Geräts von Hand bewegen. Beschädigung des Geräts VORSICHT Lehnen Sie sich nicht gegen das Gerät oder den Touchscreen. EZ2 Connect and EZ2 Connect Fx User Manual 09/2021...

  • Page 149: Elektrische Sicherheit

    Daten auf dem Typenschild des Geräts. WARNUNG Gefahr durch Stromschlag Öffnen Sie keine der Abdeckplatten des EZ2. Gefahr von Personen- und Sachschäden Es dürfen nur Wartungsarbeiten ausgeführt werden, die in diesem Benutzerhandbuch konkret beschrieben sind. EZ2 Connect and EZ2 Connect Fx User Manual 09/2021...
  • Page 150 Falls Flüssigkeit im Gerät verschüttet wurde, schalten Sie es aus, ziehen Sie den Netzstecker  und setzen Sie sich für Hilfestellung mit dem Technischen Service von QIAGEN in Verbindung, bevor Sie Maßnahmen zur Fehlerbehebung oder Inspektion ergreifen. Falls die elektrische Sicherheit bei der Bedienung des Geräts nicht mehr gewährleistet werden kann, muss das Gerät gegen Benutzung durch darüber nicht informiertes Personal gesichert werden.

  • Page 151: Betriebsbedingungen

    Direktes Sonnenlicht kann zum Ausbleichen von Teilen des Geräts führen, Schäden an Kunststoffteilen verursachen oder die Beladungsüberprüfung beeinträchtigen. Der EZ2 muss an einem Ort aufgestellt werden, an dem er vor direkter Sonneneinstrahlung geschützt ist. EZ2 Connect and EZ2 Connect Fx User Manual 09/2021...

  • Page 152: Biologische Sicherheit

    Gesundheitsschutz und Sicherheit am Arbeitsplatz eingehalten werden. * OSHA: Occupational Safety and Health Administration (USA) ACGIH: American Conference of Government Industrial Hygienists (USA) † COSHH: Control of Substances Hazardous to Health (UK) ‡ EZ2 Connect and EZ2 Connect Fx User Manual 09/2021...

  • Page 153: Chemikalien

    Dämpfe erzeugen. WARNUNG Giftige Dämpfe Verwenden Sie zum Desinfizieren von gebrauchtem Labormaterial keine Bleichmittel. Bleichmittel können mit Salzen, die in den Puffern enthalten sind, reagieren und giftige Dämpfe erzeugen. EZ2 Connect and EZ2 Connect Fx User Manual 09/2021...

  • Page 154: Abfallentsorgung

    Um einen Kontakt mit sich bewegenden Teilen beim Betrieb des EZ2 zu vermeiden, darf das Gerät nur mit geschlossener Haube betrieben werden. Sollten Haubensensor oder Haubenverriegelung nicht ordnungsgemäß funktionieren, wenden Sie sich an den Technischen Service von QIAGEN. EZ2 Connect and EZ2 Connect Fx User Manual 09/2021...

  • Page 155: Gefahr Durch Hitze

    Das EZ2 Gerät ist mit einem 2D-Barcode-Handscanner ausgestattet, mit dem Kit- und Probenbarcodes eingelesen werden können. WARNUNG Verletzungsgefahr Laserlicht der Gefahrenklasse 2: Schauen Sie bei Verwendung des Barcode- Handscanners nicht in den Laserstrahl. EZ2 Connect and EZ2 Connect Fx User Manual 09/2021...

  • Page 156: Wartungssicherheit

    Es dürfen nur Wartungsarbeiten ausgeführt werden, die in diesem Benutzerhandbuch konkret beschrieben sind. Führen Sie alle Wartungsarbeiten gemäß den Anweisungen im Abschnitt Maintenance Procedures dieses Handbuchs durch. QIAGEN stellt Reparaturen, die auf nicht fachgerecht durchgeführte Wartungsmaßnahmen zurückzuführen sind, in Rechnung. WARNUNG/ Gefahr von Personen- und Sachschäden...
  • Page 157 Auf der Arbeitsfläche verbleibende Stücke der Papiertücher könnten Zusammenstoß auf der Arbeitsplattform führen. WARNUNG/ Gefahr durch Stromschlag VORSICHT Öffnen Sie keine der Abdeckplatten des EZ2 Geräts. Es dürfen nur Wartungsarbeiten ausgeführt werden, die in diesem Benutzerhandbuch beschrieben sind. EZ2 Connect and EZ2 Connect Fx User Manual 09/2021...

  • Page 158: Symbole Auf Dem Ez2 Connect Gerät

    Symbole auf dem EZ2 Connect Gerät Die folgenden Symbole befinden sich auf dem EZ2 Connect und EZ2 Connect Fx Gerät. Symbol Beschreibung Heizsystem – im Gefahr durch Hitze – die Temperatur des Heizsystems kann bis zu Inneren des Geräts 95 °C betragen.
  • Page 159 Unique Device Identifier (UDI) als 2D-Barcode im Data Matrix-Format. Geräterückseite Typenschild an der Internationale Artikelnummer Geräterückseite Typenschild an der Seriennummer. Geräterückseite Typenschild an der Gebrauchsanweisung beachten. Geräterückseite Typenschild an der Siehe Warn- und Vorsichtshinweise. Geräterückseite EZ2 Connect and EZ2 Connect Fx User Manual 09/2021...

  • Page 160: Document Revision History

    Document Revision History Date Changes 09/2021 Initial draft of the User Manual EZ2 Connect and EZ2 Connect Fx User Manual 09/2021...
  • Page 161 ® , EZ2 ® (QIAGEN Group). Registered names, trademarks, etc. used in this document, even when not specifically marked as such, are not to be considered unprotected by law. HB-2908-001 09/2021 © 2021 QIAGEN, all rights reserved. EZ2 Connect and EZ2 Connect Fx User Manual 09/2021...
  • Page 162 Ordering www.qiagen.com/contact | Technical Support support.qiagen.com | Website www.qiagen.com EZ2 Connect and EZ2 Connect Fx User Manual 09/2021 1124549 09/2021 HB-2908-001...

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