The Focus Gradient Generator - Teledyne CombiFlash NextGen Installation And Operation Manual

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Figure 3-16 Ionization Settings
3.6 The Focus Gradient
Generator
EAR99 Technology Technology Subject to Restrictions Contained on the Cover Page
PurIon S and PurIon L systems will display a single
temperature for both positive and negative ionization.)
• Voltage (Current) – This displays a voltage setting (ESI
probes) or current value (APCI probes). Lower values
are used for more delicate compounds.
· The capillary is heated to complete the evaporation of
solvent. It also carries a voltage; lower voltages are
used for more delicate compounds.
• Source Voltage – The source voltage settings have the
greatest effect on fragmentation. Higher values induce
more fragmentation but also reduce adduct formation.
• Offset – O
FFSET
Large values tend to increase fragmentation but reduce
adduct formation.
• Span – S
voltage defines an increased voltage
PAN
applied as the mass increases. As with the offset, larger
values increase fragmentation.
• Close – Closes the window.
Once the Mass Spectrum is displayed and represents the infor-
mation you want to see, it can be printed or saved for future ref-
erence. To view more Mass labels, use the F
The fluid pressure indicator is used during troubleshooting if there
is a blockage in the fluid interface. The TIC indicator is a relative
measure of background Total Ion Count and therefore a measure
of PurIon cleanliness. It will never read completely 0; rather, it
indicates the progress of any cleaning activity performed.
PeakTrak's Focus Gradient Generator offers integrated focused
gradient method calculation. This feature runs a scouting gra-
dient on your sample to quickly find the ideal focused gradient
CombiFlash NextGen Systems
Section 3 Operation
is the voltage applied to all masses.
ORMAT
G
button.
RAPH
3-23

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Combiflash nextgen 100Combiflash nextgen 300

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