Table of Contents
Advertisement
Table 1-1 CombiFlash NextGen System Specifications
Pressure Display Accuracy 5% of full scale
Gradient Formation
Gradient Accuracy
Peak Detection Modes
Flow Cell Pathlength
UV Detection Wavelength
Wavelength Accuracy
Fraction Accuracy
Optional ELSD
Gas Inlet Pressure
Gas Consumption
Spray Chamber
Temperature
Drift Tube Temperature
Split Flow Rate
Flow Rate Range
Electrical Safety per EN 61010-1
Pollution Degree
Installation Category
Maximum Altitude
a. All specifications are subject to change.
b. For safety, maximum pressure limits are limited by each columns RFID-defined pressure limit. If the column is not RFID
recognized, see Section 1.6.5. Maximum pressure limit is also set at 200 psi for methods using a solid-load cartridge.
c.
Solvent supply containers can be located up to 0.9 m below CombiFlash NextGen systems except when using
dichloromethane. Dichloromethane containers must be at the same level as the NextGen or above.
d. The syringe pumps on the NextGen 300 have a pressure limit of 300 PSI up to 200 ml/min. Above 200 ml/min the pressure
limit drops linearly to 250 PSI. Keep in mind that other factors such as the flow path and column size may cause the max-
imum pressure limit to be reduced.
e. NextGen systems may also exhibit excessive pressure at maximum flow rates with some viscous solvents due to the tub-
ing diameter used in the system.
EAR99 Technology Technology Subject to Restrictions Contained on the Cover Page
Binary gradient from 1 and 2 solvent inlets. Binary gradient from 1, 2, and 3, 4 solvent
±2% of full scale, typical;
±5% maximum
Slope or threshold
0.1 mm, ±25%
200 to 400 nm, optional 200 to 800 nm UV-vis
±1 nm
± [2mL + (flow rate 60)]
60 to 70 psig (414 to 483 kPa)
<2.5 SLPM
Setting range: 10 to 60 °C
Minimum guaranteed temperature is 5 °C below ambient
Setting range: 30 to 90 °C
Must be 5 °C above spray chamber temperature
Maximum temperature is 60 °C above ambient
0.75 mL/min, ±10%
Minimum flow rate 5 ml/min. Lower flow rates will result in excessive detector signal
delay.
2
II
2000 meters
CombiFlash NextGen Systems
Section 1 Introduction
a
5% of full scale
inlets. Solvent selection can be
automatically controlled by the method.
±2% of full scale
1-7
Advertisement
Table of Contents
