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Figure 5-11 ESI and APCI removal from PurIon S and PurIon L
5.7.2 ESI and APCI
Replacement PurIon S
and PurIon L
5.7.3 Cleaning the
Ionization Source
Capillary
5.7.4 Replacement of Ion
Source Housing
5.7.5 Overpressure Error
EAR99 Technology Technology Subject to Restrictions Contained on the Cover Page
1. Carefully place the ion source housing on top of the base
plate and line up with the rear electrical connection. Push
down until source chamber is seated evenly across the base
plate.
2. Lock down two housing clamps at both sides.
3. Finger-tighten the ¼-28 PEEK fitting at the top of the
source housing.
Plugging of the capillary (either in the ESI or APCI probe) causes
the pressure of the carrier fluid from the fluid interface to exceed
the maximum operating pressure indicated by Error 310 or Error
316. These errors can be avoided by filtering directly injected
samples through a 0.45 µm syringe filter. To unplug the capillary,
complete the following:
1. Connect a 1 mL syringe, using adapters as needed, to the
ESI or APCI capillary and push fluid through to remove
plug. If this procedure does not resolve the issue, an HPLC
pump can be connected to the inlet fitting.
2. If this procedure fails to unplug the capillary, refer the
instructions for the rebuild kit provided with your PurIon
system.
3. Reinstall the probe following the appropriate procedures
for your system.
1. Place the ion source housing on top of the base plate and
line up with the rear electrical connection. Push down until
source chamber is seated evenly across the base plate.
2. Finger tighten the two thumb screws and finger tighten
the ¼-28 PTFE tube fitting labeled as "heated desolvation"
on the side of the housing.
The fluid interface has a pressure transducer to monitor
pressure of the carrier fluid. Since the sample is introduced at
the splitter valve, plugs usually occur between the valve and the
CombiFlash NextGen Systems
Section 5 Maintenance
5-11
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