Dissolving Solid Samples In Organics; Dissolving Solid Samples Using Acids - PerkinElmer AVIO 500 Customer Hardware And Service Manual

Dissolving Solid Samples in Organics

• Always work in a fume hood so that flammable and/or toxic solvents do not
concentrate in the work area.
• Wear protective clothing and gloves. Some solvents are readily absorbed
through the skin.
When selecting a solvent, consider the following:
• Is the solvent compatible with the equipment?
Aliphatic hydrocarbons, ketones and esters, alcohols, and xylene, are the most
frequently used solvents. Make sure that all equipment that will come into
contact with the solvent is compatible with the solvent, e.g., tubing, sample
cups, storage and waste containers, etc.
• Is the solvent toxic?
Avoid solvents known to be health hazards, such as benzene or methyl isobutyl
ketone (MIBK).
Some solvents, such as the halogenated hydrocarbons, generate toxic gases
when heated.
Consult the data sheets provided by the manufacturer for information on health
hazards (see Reference 5 on page 55).

Dissolving Solid Samples Using Acids

Dissolving solid samples in aqueous solutions often requires the use of
concentrated acids.
Using Acids
When using acids, use the following precautions:
• Always work in an acid-resistant fume hood.
• Wear protective clothing, including gloves specifically designed to resist the
acid being used.
Sample Preparation
49