Newport iServer MicroServer iTHX-M Operator's Manual page 335

For each possible allele call:
The sense and antisense RAS values for a given SNP are plotted
1.
against that SNP's three model medoids
+
Model Medoids
Sample RAS value
RAS2
Antisense
+
BB
Figure B.4
Calculating the call zone score (DTR value)
For the sample's RAS values, the call zone score for the three
2.
possible allele calls is calculated
Call Zone Score = D/R
Where:
D is the distance between the tested allele call medoid and the
sample's sense and antisense RAS values.
R is the distance between the tested allele call medoid and the
nearest alternate allele call medoid, divided by 2, as follows:
- For the AA medoid, 2R is the distance from AA to AB
- For the BB medoid, 2R is the distance from AB to BB
- For the AB medoid, 2R is the shorter of the distances from AB
to BB or AA to AB
Appendix B | MPAM Mapping Algorithm
(Figure B.4).
2R
+
AB
Call Zone Score for AA medoid = D/R
RAS1 Sense
(Figure B.4):
327
AA
+
D