Newport iServer MicroServer iTHX-M Operator's Manual page 217

two individuals or samples. The averaged IBS metric, or Mismatch
score, increases with the relatedness of the pair:
• Identical twins and samples from the same person should have
Mismatch scores ranging from 1.95 to 2.0.
• Sib pairs and parent-offspring should have Mismatch scores
ranging from 1.3 to1.8
• Unrelated pairs should have Mismatch scores from 0.9 to 1.3.
The Sample Mismatch report can be run in two modes:
• If no sample attributes are specified, all sample matches are
reported.
The report shows every chip pair with significant SNP overlap.
For more information, see
• If sample attributes are specified, the sample mismatches are also
reported.
The report can flag the following types of problems:
- .chp files with the same sample IDs but a different common
SNP pattern or gender.
- .chp files with different sample IDs but the same common
SNP pattern.
For more information, see
page 219.
For more information about the calculation of the Mismatch score, see
Sample Mismatch Algorithm, on page
To open the Sample Mismatch Report dialog box:
Click the Sample Mismatch Report button
1.
Genotyping Views shortcut bar; or
Select Tools
The Sample Mismatch report dialog box appears
Chapter 6 | Working with Mapping Data
Checking for Sample Matches, on page
Checking for Sample Mismatches, on
379.
Sample Mismatch Report... from the menu bar.
209
210.
in the
(Figure 6.26).